These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_002713.3 → NP_002704.1 nuclear inhibitor of protein phosphatase 1 isoform gamma
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) encodes the shortest isoform (gamma, also called ARD-1). It has its first exon longer at the 3' end and lacks an internal exon as compared to that of transcript variant 1. The gamma isoform uses a different translation start site and is N-terminally truncated as compared to isoform alpha encoded by variant 1. Isoform gamma contains ribonuclease activity.
- Source sequence(s)
-
AF061959, DA077576, U14575
- Consensus CDS
-
CCDS313.1
- UniProtKB/Swiss-Prot
-
Q12972
- UniProtKB/TrEMBL
-
Q6ICT4
- Related
- ENSP00000236412, OTTHUMP00000003848, ENST00000236412, OTTHUMT00000010526
-
NM_014110.4 → NP_054829.2 nuclear inhibitor of protein phosphatase 1 isoform alpha
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) is the shortest transcript but encodes the predominant and longest isoform (alpha). Isoform alpha contains protein phosphatase inhibitory actvity.
- Source sequence(s)
-
AF061959, AK292077, DA167043
- Consensus CDS
-
CCDS311.1
- UniProtKB/Swiss-Prot
-
Q12972
- UniProtKB/TrEMBL
-
Q5TEJ4
- Related
- ENSP00000311677, OTTHUMP00000003849, ENST00000311772, OTTHUMT00000010528
- Conserved Domains (1) summary
-
- cd00060
Location:27 – 126
Blast Score: 167
- FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
-
NM_138558.2 → NP_612568.1 nuclear inhibitor of protein phosphatase 1 isoform beta/delta
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) is the longest transcript and has its first exon longer at the 3' end as compared to that of transcript variant 1. The resulting isoform (beta/delta) uses a different translation start site and is N-terminally truncated as compared to isoform alpha encoded by variant 1. Isoform beta/delta contains protein phosphatase inhibitory activity.
- Source sequence(s)
-
AF061959, DA693246
- Consensus CDS
-
CCDS312.1
- UniProtKB/Swiss-Prot
-
Q12972
- Related
- ENSP00000363042, OTTHUMP00000003847, ENST00000373931, OTTHUMT00000010525
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000001.10 Reference GRCh37.p5 Primary Assembly
- Range
- 28157252..28178183
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000133.1 Alternate HuRef
- Range
- 26413444..26434413
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)