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FEZF2 FEZ family zinc finger 2 [ Homo sapiens (human) ]

Gene ID: 55079, updated on 26-May-2016
Official Symbol
FEZF2provided by HGNC
Official Full Name
FEZ family zinc finger 2provided by HGNC
Primary source
HGNC:HGNC:13506
See related
Ensembl:ENSG00000153266 HPRD:07596; MIM:607414; Vega:OTTHUMG00000158705
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FEZ; TOF; FEZL; FKSG36; ZFP312; ZNF312
Orthologs
Location:
3p14.2
Exon count:
5
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 3 NC_000003.12 (62369672..62373515, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (62355347..62359190, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase, receptor type G Neighboring gene PTPRG antisense RNA 1 Neighboring gene uncharacterized LOC105377647 Neighboring gene chromosome 3 open reading frame 14 Neighboring gene Ca2+ dependent secretion activator Neighboring gene ribosomal protein L14 pseudogene 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Replication interactions

Interaction Pubs
Knockdown of FEZ family zinc finger 2 (FEZF2) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Go to the HIV-1, Human Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ10142

Gene Ontology Provided by GOA

Process Evidence Code Pubs
axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
 
axonal fasciculation IEA
Inferred from Electronic Annotation
more info
 
cerebral cortex GABAergic interneuron migration IEA
Inferred from Electronic Annotation
more info
 
commitment of neuronal cell to specific neuron type in forebrain IEA
Inferred from Electronic Annotation
more info
 
dendrite development IEA
Inferred from Electronic Annotation
more info
 
dentate gyrus development IEA
Inferred from Electronic Annotation
more info
 
forebrain anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 
locomotory behavior IEA
Inferred from Electronic Annotation
more info
 
negative regulation of cell proliferation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
 
neuron fate determination IEA
Inferred from Electronic Annotation
more info
 
positive regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
regulation of axon guidance IEA
Inferred from Electronic Annotation
more info
 
transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
fez family zinc finger protein 2
Names
forebrain embryonic zinc finger-like protein 2
testis tissue sperm-binding protein Li 80P
zinc finger protein 312

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018008.3NP_060478.3  fez family zinc finger protein 2

    See identical proteins and their annotated locations for NP_060478.3

    Status: VALIDATED

    Source sequence(s)
    BC022464, BM930804, DA492936, DR002892, H28929
    Consensus CDS
    CCDS2897.1
    UniProtKB/Swiss-Prot
    Q8TBJ5
    Related
    ENSP00000283268, OTTHUMP00000213299, ENST00000283268, OTTHUMT00000351813
    Conserved Domains (4) summary
    COG5048
    Location:289395
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam11931
    Location:264295
    DUF3449; Domain of unknown function (DUF3449)
    pfam13465
    Location:322344
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:279299
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p2 Primary Assembly

    Range
    62369672..62373515 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011533881.1XP_011532183.1  

    Conserved Domains (4) summary
    COG5048
    Location:331482
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam11931
    Location:306337
    DUF3449; Domain of unknown function (DUF3449)
    pfam13465
    Location:364386
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:321341
    ZF_C2H2; C2H2 Zn finger [structural motif]

Alternate CHM1_1.1

Genomic

  1. NC_018914.2 Alternate CHM1_1.1

    Range
    62306475..62310318 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)