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    PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme [ Homo sapiens ]

    Gene ID: 5500, updated on 19-May-2012
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    Summary

    Official Symbol
    PPP1CBprovided by HGNC
    Official Full Name
    protein phosphatase 1, catalytic subunit, beta isozymeprovided by HGNC
    Primary source
    HGNC:9282
    See related
    Ensembl:ENSG00000213639; HPRD:11792; MIM:600590; Vega:OTTHUMG00000152011
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PP-1B; PPP1CD; PP1beta; MGC3672
    Summary
    The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
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    Genomic context

    Location :
    2p23
    Sequence :
    Chromosome: 2; NC_000002.11 (28974614..29025806)
    See PPP1CB in Epigenomics, MapViewer

    Chromosome 2 - NC_000002.11Genomic Context describing neighboring genes Neighboring gene phospholipase B1 Neighboring gene uncharacterized LOC100505774 Neighboring gene speedy homolog A (Xenopus laevis) Neighboring gene tRNA methyltransferase 61 homolog B (S. cerevisiae) Neighboring gene WD repeat domain 43 Neighboring gene small nucleolar RNA, C/D box 92

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. Lee KA, et al. J Biol Chem, 2011 Dec 2. PMID 21987572.
    2. Global identification of modular cullin-RING ligase substrates. Emanuele MJ, et al. Cell, 2011 Oct 14. PMID 21963094.
    3. Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, et al. Mol Cell, 2011 Oct 21. PMID 21906983.
    4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Wagner SA, et al. Mol Cell Proteomics, 2011 Oct. PMID 21890473.
    5. Rapid dephosphorylation of G protein-coupled receptors by protein phosphatase 1β is required for termination of β-arrestin-dependent signaling. Pöll F, et al. J Biol Chem, 2011 Sep 23. PMID 21795688.

    See all (65) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Protein phosphatase 1beta (PP1beta) is identified as a phosphatase for the cluster of phosphorylated threonines ((353)TTETQRT(359)) within the sst(2A) somatostatin receptor carboxyl terminus that mediates beta-arrestin binding using siRNA knock-down sc...
      Title: Rapid dephosphorylation of G protein-coupled receptors by protein phosphatase 1β is required for termination of β-arrestin-dependent signaling.
    2. PPP1CB is over expressed in malignant melanoma.
      Title: Differential expression patterns of capping protein, protein phosphatase 1, and casein kinase 1 may serve as diagnostic markers for malignant melanoma.
    3. Data suggest that double-thiophosphorylation of TIMAP has minor effect on its binding ability to PP1c, but considerably attenuates its inhibitory effect on the activity of PP1c.
      Title: Characterization of the effect of TIMAP phosphorylation on its interaction with protein phosphatase 1.
    4. serine/threonine protein phosphatase PP1beta is a physiological Nucleophosmin (NPM) phosphatase under both the genotoxic stress and growth conditions.
      Title: Dephosphorylation of nucleophosmin by PP1β facilitates pRB binding and consequent E2F1-dependent DNA repair.
    5. PP-1 ( PP-1alpha or PP-1beta ) acts as a major phosphatase to dephosphorylate AKT1 at Thr-450 and thus modulate its functions in regulating gene expression, cell survival and differentiation.
      Title: Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation.
    6. mammalian Wdr82 functions in a variety of cellular processes; PTW/PP1 phosphatase complex (PNUTS, Tox4, Wdr82, PP1) has a role in the regulation of chromatin structure during the transition from mitosis into interphase
      Title: Identification and characterization of a novel human PP1 phosphatase complex.
    7. Observational study of gene-disease association. (HuGE Navigator)
      Title: Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
    8. R16A at the membrane may mediate the PB signal to initiate CAR nuclear translocation, through a mechanism including its dimerization and inhibition of PP1beta activity.
      Title: PPP1R16A, the membrane subunit of protein phosphatase 1beta, signals nuclear translocation of the nuclear receptor constitutive active/androstane receptor.
    9. In this study, we show that protein phosphatase-1 (PP1) inhibitor-3 (Inh3) is localized to the nucleoli and centrosomes in interphase HEK 293 cells.
      Title: Protein phosphatase-1 inhibitor-3 is co-localized to the nucleoli and centrosomes with PP1gamma1 and PP1alpha, respectively.
    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

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    HIV-1 protein interactions

    Protein Gene Interaction Pubs
    Envelope surface glycoprotein gp120 env Genes, including GABRP, ADF, HINT, PRSS2, SDCBP, PTK9, PPP2R5B, ITGA3, PRKCBP1, HMOX2, HAT1, PPP1cB, and ICAM-1, are upregulated after treatment of human astrocytes with HIV-1 gp120 PubMed
    Tat tat PP1 interacts with Tat in part through the binding of Val(36) and Phe(38) of Tat to PP1, and Tat is involved in the nuclear and subnuclear targeting of PP1 PubMed
    tat Protein phosphatase-2A (PP2A) and protein phosphatase-1 (PP1) regulate HIV-1 Tat-activated transcription through dephosphorylation of CDK9 PubMed
    tat Stimulation of HIV-1 Tat transactivation by protein phosphatase 1 (PP1) is inhibited by nuclear inhibitor of PP1 (NIPP1), indicating Tat function is regulated by PP1/NIPP1 PubMed
    tat Protein phosphatase 1 (PP1) associates with HIV-1 Tat and stimulates Tat-mediated transactivation of the HIV-1 LTR promoter PubMed

    Go to the HIV-1, Human Protein Interaction Database

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    P62140 O60237 PPP1R12B    HPRD  PubMed  
    P62140 Protein phosphatase 1, regulatory subunit 12C PPP1R12C    HPRD  PubMed  
    P62140 P13861 PRKAR2A    HPRD  PubMed  
    P62140 Q05397 PTK2    HPRD  PubMed  
    P62140 P06400 RB1    HPRD  PubMed  
    P62140 P31314 TLX1    HPRD  PubMed  
    P62140 Q9Y2W2 WBP11    HPRD  PubMed  
    P62140 O95405 ZFYVE9    HPRD  PubMed  
    BioGRID:111494 BioGRID:116384 AKAP11    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:111494 BioGRID:107140 BRCA1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:111494 BioGRID:216776 Cep72    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:119613 HDAC7    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:111494 BioGRID:117596 INTS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:117717 INTS6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:110771 NCL    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:111494 BioGRID:114973 NCOR1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:111494 BioGRID:110904 NONO    BioGRID  PubMed Reconstituted Complex 
    BioGRID:111494 BioGRID:111506 PPP1R10    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:111494 BioGRID:112852 PPP1R11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:110742 PPP1R12A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:110743 PPP1R12B    BioGRID  PubMed Reconstituted Complex 
    BioGRID:111494 BioGRID:117172 PPP1R15A    BioGRID  PubMed Affinity Capture-Western; Phenotypic Suppression 
    BioGRID:111494 BioGRID:111497 PPP1R2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:111502 PPP1R7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:111503 PPP1R8    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:111494 BioGRID:124202 PPP1R9B    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:111494 BioGRID:111719 PTK2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:111494 BioGRID:206343 Ppp1r10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:112174 RYR2    BioGRID  PubMed Co-fractionation 
    BioGRID:111494 BioGRID:121977 SH2D4A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:112482 SMARCB1    BioGRID  PubMed Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex 
    BioGRID:111494 BioGRID:215561 Sass6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:120462 TMEM33    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:115209 TOX4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:111494 BioGRID:115457 TRIM28    BioGRID  PubMed Affinity Capture-Western; Co-localization; Reconstituted Complex 
    BioGRID:111494 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:111494 BioGRID:123245 WDR82    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
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    General gene information

    Markers

    Genotypes

    Potential readthrough

    Included gene: SPDYA

    Homology

    • Homologs of the PPP1CB gene: The PPP1CB gene is conserved in chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, A.thaliana, and rice.
    • Map Viewer (Mouse, Rat)

    Pathways from BioSystems

    • Alcoholism, organism-specific biosystem (from KEGG)
      Alcoholism, organism-specific biosystemAlcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the reward...
    • Alcoholism, conserved biosystem (from KEGG)
      Alcoholism, conserved biosystemAlcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the reward...
    • Amphetamine addiction, organism-specific biosystem (from KEGG)
      Amphetamine addiction, organism-specific biosystemAmphetamine is a psychostimulant drug that exerts persistent addictive effects. Most addictive drugs increase extracellular concentrations of dopamine (DA) in nucleus accumbens (NAc) and medial prefr...
    • Amphetamine addiction, conserved biosystem (from KEGG)
      Amphetamine addiction, conserved biosystemAmphetamine is a psychostimulant drug that exerts persistent addictive effects. Most addictive drugs increase extracellular concentrations of dopamine (DA) in nucleus accumbens (NAc) and medial prefr...
    • Dopaminergic synapse, organism-specific biosystem (from KEGG)
      Dopaminergic synapse, organism-specific biosystemDopamine (DA) is an important and prototypical slow neurotransmitter in the mammalian brain, where it controls a variety of functions including locomotor activity, motivation and reward, learning an...
    • Dopaminergic synapse, conserved biosystem (from KEGG)
      Dopaminergic synapse, conserved biosystemDopamine (DA) is an important and prototypical slow neurotransmitter in the mammalian brain, where it controls a variety of functions including locomotor activity, motivation and reward, learning an...
    • Focal adhesion, organism-specific biosystem (from KEGG)
      Focal adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
    • Focal adhesion, conserved biosystem (from KEGG)
      Focal adhesion, conserved biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
    • G13 Signaling Pathway, organism-specific biosystem (from WikiPathways)
      G13 Signaling Pathway, organism-specific biosystemThe G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cell...
    • Herpes simplex infection, organism-specific biosystem (from KEGG)
      Herpes simplex infection, organism-specific biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
    • Herpes simplex infection, conserved biosystem (from KEGG)
      Herpes simplex infection, conserved biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
    • Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis, organism-specific biosystem (from REACTOME)
      Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis, organism-specific biosystemTriacylglycerol is a major energy store in the body and its hydrolysis to yield fatty acids and glycerol is a tightly regulated part of energy metabolism. A central part in this regulation is played ...
    • Insulin signaling pathway, organism-specific biosystem (from KEGG)
      Insulin signaling pathway, organism-specific biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...
    • Insulin signaling pathway, conserved biosystem (from KEGG)
      Insulin signaling pathway, conserved biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...
    • Lipid digestion, mobilization, and transport, organism-specific biosystem (from REACTOME)
      Lipid digestion, mobilization, and transport, organism-specific biosystemProcesses annotated here include the digestion of dietary lipids, sterol uptake, the formation and turnover of lipoproteins (chylomicrons, VLDL, LDL, and HDL), and the mobilization of fatty acids thr...
    • Long-term potentiation, organism-specific biosystem (from KEGG)
      Long-term potentiation, organism-specific biosystemHippocampal long-term potentiation (LTP), a long-lasting increase in synaptic efficacy, is the molecular basis for learning and memory. Tetanic stimulation of afferents in the CA1 region of the hippo...
    • Long-term potentiation, conserved biosystem (from KEGG)
      Long-term potentiation, conserved biosystemHippocampal long-term potentiation (LTP), a long-lasting increase in synaptic efficacy, is the molecular basis for learning and memory. Tetanic stimulation of afferents in the CA1 region of the hippo...
    • Metabolism, organism-specific biosystem (from REACTOME)
      Metabolism, organism-specific biosystemMetabolic processes in human cells generate energy through the oxidation of molecules consumed in the diet and mediate the synthesis of diverse essential molecules not taken in the diet as well as th...
    • Metabolism of lipids and lipoproteins, organism-specific biosystem (from REACTOME)
      Metabolism of lipids and lipoproteins, organism-specific biosystemLipids are hydrophobic but otherwise chemically diverse molecules that play a wide variety of roles in human biology. They include ketone bodies, fatty acids, triacylglycerols, phospholipids and sphi...
    • Oocyte meiosis, organism-specific biosystem (from KEGG)
      Oocyte meiosis, organism-specific biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, homologous chromosomes recombine and then segrega...
    • Oocyte meiosis, conserved biosystem (from KEGG)
      Oocyte meiosis, conserved biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, homologous chromosomes recombine and then segrega...
    • PLK1 signaling events, organism-specific biosystem (from Pathway Interaction Database)
      PLK1 signaling events, organism-specific biosystem
      PLK1 signaling events
    • Regulation of actin cytoskeleton, organism-specific biosystem (from KEGG)
      Regulation of actin cytoskeleton, organism-specific biosystem
      Regulation of actin cytoskeleton
    • Regulation of actin cytoskeleton, conserved biosystem (from KEGG)
      Regulation of actin cytoskeleton, conserved biosystem
      Regulation of actin cytoskeleton
    • Vascular smooth muscle contraction, organism-specific biosystem (from KEGG)
      Vascular smooth muscle contraction, organism-specific biosystemThe vascular smooth muscle cell (VSMC) is a highly specialized cell whose principal function is contraction. On contraction, VSMCs shorten, thereby decreasing the diameter of a blood vessel to regula...
    • Vascular smooth muscle contraction, conserved biosystem (from KEGG)
      Vascular smooth muscle contraction, conserved biosystemThe vascular smooth muscle cell (VSMC) is a highly specialized cell whose principal function is contraction. On contraction, VSMCs shorten, thereby decreasing the diameter of a blood vessel to regula...
    • mRNA surveillance pathway, organism-specific biosystem (from KEGG)
      mRNA surveillance pathway, organism-specific biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...
    • mRNA surveillance pathway, conserved biosystem (from KEGG)
      mRNA surveillance pathway, conserved biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    myosin phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    myosin-light-chain-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		  
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    		  
    Process Evidence Code Pubs
    carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    glycogen metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    lipid metabolic process TAS
    Traceable Author Statement
    more info
    		  
    protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    regulation of cell adhesion IDA
    Inferred from Direct Assay
    more info
    		  
    regulation of glycogen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    regulation of glycogen catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    small molecule metabolic process TAS
    Traceable Author Statement
    more info
    		  
    triglyceride catabolic process TAS
    Traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    MLL5-L complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    PTW/PP1 phosphatase complex IDA
    Inferred from Direct Assay
    more info
    		  
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    glycogen granule IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein phosphatase type 1 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    serine/threonine-protein phosphatase PP1-beta catalytic subunit
    Names
    serine/threonine-protein phosphatase PP1-beta catalytic subunit
    protein phosphatase 1-beta
    protein phosphatase 1-delta
    protein phosphatase 1, catalytic subunit, beta isoform
    protein phosphatase 1, catalytic subunit, delta isoform
    serine/threonine protein phosphatase PP1-beta catalytic subunit
    NP_002700.1
    NP_996759.1
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_002709.2 → NP_002700.1  serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. It encodes the longer isoform (1).
      Source sequence(s)
      BC002697, BE047402, BI551898, BM835970, BX477003, BX647295, CD722576, X80910
      Consensus CDS
      CCDS33169.1
      UniProtKB/Swiss-Prot
      P62140
      Related
      ENSP00000378769, OTTHUMP00000200967, ENST00000395366, OTTHUMT00000324841
      Conserved Domains (2) summary
      cd07414
      Location:7 – 299
      Blast Score: 1758
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
      PTZ00480
      Location:4 – 300
      Blast Score: 1428
      PTZ00480; serine/threonine-protein phosphatase; Provisional

    2. NM_206876.1 → NP_996759.1  serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Both variants encode the same isoform (1).
      Source sequence(s)
      AF092905, BE047402, BI551898, BM835970, BQ933435, CB111140, CD656807, CD722576, X80910
      Consensus CDS
      CCDS33169.1
      UniProtKB/Swiss-Prot
      P62140
      Related
      ENSP00000351298, ENST00000358506
      Conserved Domains (2) summary
      cd07414
      Location:7 – 299
      Blast Score: 1758
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
      PTZ00480
      Location:4 – 300
      Blast Score: 1428
      PTZ00480; serine/threonine-protein phosphatase; Provisional

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000002.11 Reference GRCh37.p5 Primary Assembly

      Range
      28974614..29025806
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000134.1 Alternate HuRef

      Range
      28716532..28767764
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_206877.1: Suppressed sequence

      Description
      NM_206877.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Help top of page

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC097724.6 AAY24124.1
    genomic CH471053.2 EAX00527.1
      EAX00528.1
      EAX00529.1
      EAX00530.1
    genomic U11005.1 AAA85093.1
    mRNA AF092905.1 AAF01137.1
    mRNA AI147919.1 None
    mRNA AK295957.1 BAG58737.1
    mRNA AK303682.1 BAG64675.1
    mRNA AK312329.1 BAG35251.1
    mRNA AK316532.1 BAH14903.1
    mRNA BC002697.2 AAH02697.1
    mRNA BC012045.1 AAH12045.1
    mRNA BE047402.1 None
    mRNA BI551898.1 None
    mRNA BM835970.1 None
    mRNA BQ933435.1 None
    mRNA BT019744.1 AAV38549.1
    mRNA BU740022.1 None
    mRNA BX477003.1 None
    mRNA BX647295.1 None
    mRNA BX647970.1 None
    mRNA CB111140.1 None
    mRNA CD656807.1 None
    mRNA CD722576.1 None
    mRNA CR542263.1 CAG47059.1
    mRNA CR542285.1 CAG47080.1
    mRNA X80910.1 CAA56870.1
    other-genetic AM392772.1 CAL37650.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P62140.3 GenPept UniProtKB/Swiss-Prot:P62140
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Medical
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

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