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rasgef1b RasGEF domain family member 1B [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 549667, updated on 5-Mar-2024

Summary

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Official Symbol
rasgef1bprovided by Xenbase
Official Full Name
RasGEF domain family member 1Bprovided by Xenbase
Primary source
Xenbase:XB-GENE-1015760
See related
Ensembl:ENSXETG00000012564
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
18
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (82121349..82288387, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (88437999..88467847, complement)

Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene solute carrier family 10 (sodium/bile acid cotransporter), member 6 Neighboring gene protein tyrosine phosphatase non-receptor type 13 Neighboring gene heterogeneous nuclear ribonucleoprotein D Neighboring gene heterogeneous nuclear ribonucleoprotein D like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
enables guanyl-nucleotide exchange factor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in Ras protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ras-GEF domain-containing family member 1B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001016913.2 → NP_001016913.1  ras-GEF domain-containing family member 1B

    See identical proteins and their annotated locations for NP_001016913.1

    Status: PROVISIONAL

    Source sequence(s)
    CR848333
    UniProtKB/Swiss-Prot
    Q28EC1
    UniProtKB/TrEMBL
    A0A6I8Q2T0, B1H0X4
    Related
    ENSXETP00000064422.2, ENSXETT00000069534.2
    Conserved Domains (2) summary
    cd06224
    Location:42 → 166
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:208 → 402
    RasGEF; RasGEF domain

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    82121349..82288387 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031900210.1 → XP_031756070.1  ras-GEF domain-containing family member 1B isoform X1

    UniProtKB/TrEMBL
    A0A6I8R9T9, A0A8J1JGD8
    Conserved Domains (2) summary
    cd06224
    Location:157 → 281
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:323 → 518
    RasGEF; RasGEF domain

  2. XM_031900213.1 → XP_031756073.1  ras-GEF domain-containing family member 1B isoform X2

    UniProtKB/TrEMBL
    A0A6I8QKQ6, A0A6I8R9T9
    Related
    ENSXETP00000069141.2, ENSXETT00000087874.2
    Conserved Domains (2) summary
    cd06224
    Location:157 → 281
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:323 → 517
    RasGEF; RasGEF domain

  3. XM_031900231.1 → XP_031756091.1  ras-GEF domain-containing family member 1B isoform X5

    UniProtKB/Swiss-Prot
    Q28EC1
    UniProtKB/TrEMBL
    A0A6I8Q2T0, B1H0X4
    Conserved Domains (2) summary
    cd06224
    Location:42 → 166
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:208 → 402
    RasGEF; RasGEF domain

  4. XM_031900226.1 → XP_031756086.1  ras-GEF domain-containing family member 1B isoform X4

    UniProtKB/TrEMBL
    A0A6I8Q2T0, G1K3F5
    Related
    ENSXETP00000027482.5, ENSXETT00000027482.5
    Conserved Domains (2) summary
    cd06224
    Location:42 → 166
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:208 → 403
    RasGEF; RasGEF domain

  5. XM_012963029.3 → XP_012818483.1  ras-GEF domain-containing family member 1B isoform X3

    UniProtKB/TrEMBL
    A0A6I8Q2T0, A0A6I8RXW5
    Related
    ENSXETP00000090078.2, ENSXETT00000081267.2
    Conserved Domains (2) summary
    cd06224
    Location:87 → 211
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:253 → 448
    RasGEF; RasGEF domain

  6. XM_018093589.2 → XP_017949078.1  ras-GEF domain-containing family member 1B isoform X4

    UniProtKB/TrEMBL
    A0A6I8Q2T0, G1K3F5
    Conserved Domains (2) summary
    cd06224
    Location:42 → 166
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:208 → 403
    RasGEF; RasGEF domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q28EC1.1 GenPept UniProtKB/Swiss-Prot:Q28EC1

Gene LinkOut

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