These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_011678.1 RefSeqGene
- Range
- 5001..70743
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001033556.1 → NP_001028728.1 protein phosphatase 1B isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The resulting protein (isoform 4) has a distinct and shorter C-terminus, compared to isoform 1.
- Source sequence(s)
-
AA769851, BF979498, DQ023509
- Consensus CDS
-
CCDS46272.1
- Related
- ENSP00000387341, ENST00000409895
- Conserved Domains (3) summary
-
- cd00143
Location:23 – 295
Blast Score: 650
- PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
- pfam07830
Location:289 – 321
Blast Score: 159
- PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain
- pfam00481
Location:22 – 288
Blast Score: 637
- PP2C; Protein phosphatase 2C
-
NM_001033557.1 → NP_001028729.1 protein phosphatase 1B isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) uses an alternate splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 5) has a distinct and shorter C-terminus, compared to isoform 1.
- Source sequence(s)
-
BC012002, BF979498, DQ023510
- Consensus CDS
-
CCDS46271.1
- UniProtKB/Swiss-Prot
-
O75688
- Related
- ENSP00000387287, OTTHUMP00000202394, ENST00000409432, OTTHUMT00000327845
- Conserved Domains (3) summary
-
- cd00143
Location:23 – 295
Blast Score: 654
- PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
- pfam07830
Location:289 – 369
Blast Score: 382
- PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain
- pfam00481
Location:22 – 288
Blast Score: 640
- PP2C; Protein phosphatase 2C
-
NM_002706.4 → NP_002697.1 protein phosphatase 1B isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
BC064381, BF979498, DQ023510
- Consensus CDS
-
CCDS1817.1
- UniProtKB/Swiss-Prot
-
O75688
- UniProtKB/TrEMBL
-
Q658R4
- Related
- ENSP00000282412, OTTHUMP00000158953, ENST00000282412, OTTHUMT00000250672
- Conserved Domains (3) summary
-
- cd00143
Location:23 – 295
Blast Score: 656
- PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
- pfam07830
Location:289 – 369
Blast Score: 381
- PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain
- pfam00481
Location:22 – 288
Blast Score: 642
- PP2C; Protein phosphatase 2C
-
NM_177968.2 → NP_808907.1 protein phosphatase 1B isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 3' region, which includes a part of the coding region and 3' UTR, as compared to variant 1. The resulting isoform (2) has a distinct and shorter C-terminus, as compared to isoform 1.
- Source sequence(s)
-
BF979498, DQ023508
- Consensus CDS
-
CCDS1816.1
- UniProtKB/Swiss-Prot
-
O75688
- Related
- ENSP00000367813, OTTHUMP00000158954, ENST00000378551, OTTHUMT00000250673
- Conserved Domains (3) summary
-
- cd00143
Location:23 – 295
Blast Score: 653
- PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
- pfam07830
Location:289 – 369
Blast Score: 382
- PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain
- pfam00481
Location:22 – 288
Blast Score: 639
- PP2C; Protein phosphatase 2C
-
NM_177969.2 → NP_808908.1 protein phosphatase 1B isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an internal segment, which includes a part of the coding region, as compared to variant 1. The translation begins at a downstream start codon, resulting in an isoform (3) that has a shorter N-terminus, as compared to isoform 1.
- Source sequence(s)
-
BC012002, BF979498, DQ023510
- Consensus CDS
-
CCDS1818.1
- UniProtKB/Swiss-Prot
-
O75688
- Related
- ENSP00000326089, OTTHUMP00000158955, ENST00000345249, OTTHUMT00000250674
- Conserved Domains (1) summary
-
- pfam07830
Location:2 – 82
Blast Score: 360
- PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000002.11 Reference GRCh37.p5 Primary Assembly
- Range
- 44396000..44461742
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000134.1 Alternate HuRef
- Range
- 44132461..44198020
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)