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YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 [ Homo sapiens (human) ]

Gene ID: 54915, updated on 20-Aug-2015
Official Symbol
YTHDF1provided by HGNC
Official Full Name
YTH N(6)-methyladenosine RNA binding protein 1provided by HGNC
Primary source
HGNC:HGNC:15867
See related
Ensembl:ENSG00000149658; HPRD:11691; MIM:616529; Vega:OTTHUMG00000032955
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C20orf21
Orthologs
See YTHDF1 in Epigenomics, MapViewer
Location:
20q13.33
Exon count:
5
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 20 NC_000020.11 (63195429..63216186, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (61826781..61847538, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372719 Neighboring gene uncharacterized LOC105376996 Neighboring gene microRNA 124-3 Neighboring gene microRNA 3196 Neighboring gene baculoviral IAP repeat containing 7 Neighboring gene Na+/K+ transporting ATPase interacting 4 Neighboring gene uncharacterized LOC100192386

NHGRI GWAS Catalog

Description
Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ20391

Gene Ontology Provided by GOA

Function Evidence Code Pubs
N6-methyladenosine-containing RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
poly(A) RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
ribosome binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
positive regulation of translational initiation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
YTH domain-containing family protein 1
Names
DACA-1
YTH domain family 1
YTH domain family protein 1
YTH domain family, member 1
dermatomyositis associated with cancer putative autoantigen 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017798.3NP_060268.2  YTH domain-containing family protein 1

    See identical proteins and their annotated locations for NP_060268.2

    Status: VALIDATED

    Source sequence(s)
    BC003681, BC050284
    Consensus CDS
    CCDS13511.1
    UniProtKB/Swiss-Prot
    Q9BYJ9
    Related
    ENSP00000359364, OTTHUMP00000031533, ENST00000370339, OTTHUMT00000080110
    Conserved Domains (2) summary
    pfam04146
    Location:390525
    YTH; YT521-B-like domain
    cl09930
    Location:258311
    RPA_2b-aaRSs_OBF_like; Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p2 Primary Assembly

    Range
    63195429..63216186
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018931.2 Alternate CHM1_1.1

    Range
    61727941..61748702
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)