RefSeqs maintained independently of Annotated Genomes
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_023292.1 RefSeqGene
- Range
- 5001..112231
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_017778.2 → NP_060248.2 histone-lysine N-methyltransferase NSD3 isoform short
Status: REVIEWED
- Description
- Transcript variant: This variant (short) contains an alternative 3' end sequence. The shorter protein encoded has a different carboxy terminus than the protein encoded by variant long.
- Source sequence(s)
-
AF332468
- Consensus CDS
-
CCDS6105.1
- UniProtKB/Swiss-Prot
-
Q9BZ95
- Related
- ENSP00000313410, OTTHUMP00000228479, ENST00000316985, OTTHUMT00000381925
- Conserved Domains (1) summary
-
- cd05837
Location:267 – 383
Blast Score: 409
- MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
-
NM_023034.1 → NP_075447.1 histone-lysine N-methyltransferase NSD3 isoform long
Status: REVIEWED
- Description
- Transcript variant: This variant (long) contains an alternative 3' end sequence. The longer protein encoded has a different carboxy terminus than the protein encoded by variant short.
- Source sequence(s)
-
AF332469
- Consensus CDS
-
CCDS43729.1
- UniProtKB/Swiss-Prot
-
Q9BZ95
- Related
- ENSP00000313983, OTTHUMP00000228478, ENST00000317025, OTTHUMT00000381924
- Conserved Domains (6) summary
-
- COG5034
Location:613 – 746
Blast Score: 89
- TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
- cd05837
Location:267 – 383
Blast Score: 410
- MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
- cd05838
Location:958 – 1051
Blast Score: 450
- WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
- smart00570
Location:1094 – 1144
Blast Score: 140
- AWS; associated with SET domains
- cl02566
Location:1145 – 1268
Blast Score: 377
- SET; SET domain
- cl15348
Location:915 – 955
Blast Score: 111
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
RefSeqs of Annotated Genomes: Build 37.3
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000008.10 Reference GRCh37.p5 Primary Assembly
- Range
- 38132560..38239790, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000140.1 Alternate HuRef
- Range
- 36666622..36774003, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)