proc protein C (inactivator of coagulation factors Va and VIIIa) [Xenopus (Silurana) tropicalis (western clawed frog)] - Gene

Summary

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Official Symbol: procprovided by Xenbase
Official Full Name: protein C (inactivator of coagulation factors Va and VIIIa)provided by Xenbase
Primary source: Xenbase:XB-GENE-973141
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus (Silurana) tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: proc1

Genomic context

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Location :: chromosome: Un

See proc in MapViewer

NW_003163550.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

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Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from BioSystems

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Cell surface interactions at the vascular wall, organism-specific biosystem (from REACTOME)
Cell surface interactions at the vascular wall, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Common Pathway, organism-specific biosystem (from REACTOME)
Common Pathway, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem (from REACTOME)
Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystemcomputationally inferred pathway (not manually curated)
Gamma-carboxylation of protein precursors, organism-specific biosystem (from REACTOME)
Gamma-carboxylation of protein precursors, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins, organism-specific biosystem (from REACTOME)
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Hemostasis, organism-specific biosystem (from REACTOME)
Hemostasis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Metabolism of proteins, organism-specific biosystem (from REACTOME)
Metabolism of proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, organism-specific biosystem (from REACTOME)
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Post-translational protein modification, organism-specific biosystem (from REACTOME)
Post-translational protein modification, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Removal of aminoterminal propeptides from gamma-carboxylated proteins, organism-specific biosystem (from REACTOME)
Removal of aminoterminal propeptides from gamma-carboxylated proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus, organism-specific biosystem (from REACTOME)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus, organism-specific biosystemcomputationally inferred pathway (not manually curated)

General protein information

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Preferred Names: protein C (inactivator of coagulation factors Va and VIIIa)

Names: protein C (inactivator of coagulation factors Va and VIIIa)

NP_001015759.1

EC 3.4.21.69

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001015759.1 → NP_001015759.1 protein C (inactivator of coagulation factors Va and VIIIa) precursor

Status: PROVISIONAL

Source sequence(s)

BC089695

UniProtKB/TrEMBL

Q5FVZ2

Conserved Domains (4) summary

cd00054
Location:94 – 129
Blast Score: 94

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00190
Location:198 – 427
Blast Score: 649

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

smart00069
Location:32 – 93
Blast Score: 208

GLA; Domain containing Gla (gamma-carboxyglutamate) residues.

cl09941
Location:137 – 168
Blast Score: 83

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

RefSeqs of Annotated Genomes: Build 1.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly (based on v4.2)

Genomic

NW_003163550.1 Reference assembly (based on v4.2)

Range

1493862..1507941, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AAMC01060123.1 (1563..3363)	None
genomic	AAMC01060124.1 (2..1140)	None
genomic	AAMC01060125.1 (2..953)	None
genomic	AAMC01060126.1 (2..9088)	None
mRNA	BC089695.1	AAH89695.1