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Prdx5 peroxiredoxin 5 [ Mus musculus (house mouse) ]

Gene ID: 54683, updated on 21-May-2016
Official Symbol
Prdx5provided by MGI
Official Full Name
peroxiredoxin 5provided by MGI
Primary source
MGI:MGI:1859821
See related
Ensembl:ENSMUSG00000024953
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AOPP; PrxV; Pmp20; Prdx6; AOEB166
Orthologs
Location:
19 A; 19 5.08 cM
Exon count:
6
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 19 NC_000085.6 (6906819..6909645, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (6981309..6984135, complement)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 88B Neighboring gene predicted gene, 41801 Neighboring gene tRNA methyltransferase 11-2 Neighboring gene estrogen related receptor, alpha Neighboring gene microRNA 6990

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
RNA polymerase III regulatory region DNA binding ISO
Inferred from Sequence Orthology
more info
 
antioxidant activity ISO
Inferred from Sequence Orthology
more info
 
antioxidant activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
cysteine-type endopeptidase inhibitor activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
peroxidase activity ISO
Inferred from Sequence Orthology
more info
 
peroxiredoxin activity ISO
Inferred from Sequence Orthology
more info
 
peroxynitrite reductase activity ISO
Inferred from Sequence Orthology
more info
 
protein dimerization activity ISO
Inferred from Sequence Orthology
more info
 
receptor binding ISO
Inferred from Sequence Orthology
more info
 
receptor binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
thioredoxin peroxidase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
NADPH oxidation ISO
Inferred from Sequence Orthology
more info
 
cellular response to reactive oxygen species ISO
Inferred from Sequence Orthology
more info
 
hydrogen peroxide catabolic process ISO
Inferred from Sequence Orthology
more info
 
hydrogen peroxide catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of oxidoreductase activity ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription from RNA polymerase III promoter ISO
Inferred from Sequence Orthology
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of collagen biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
reactive nitrogen species metabolic process ISO
Inferred from Sequence Orthology
more info
 
regulation of apoptosis involved in tissue homeostasis ISO
Inferred from Sequence Orthology
more info
 
response to oxidative stress ISO
Inferred from Sequence Orthology
more info
 
response to oxidative stress ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
cytoplasmic vesicle ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
peroxisomal matrix ISO
Inferred from Sequence Orthology
more info
 
peroxisomal matrix ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
peroxisome ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
peroxiredoxin-5, mitochondrial
Names
PLP
antioxidant enzyme B166
liver tissue 2D-page spot 2D-0014IV
peroxiredoxin 6
peroxiredoxin V
peroxisomal antioxidant enzyme
peroxisomal membrane protein 20
prx-V
thioredoxin peroxidase PMP20
thioredoxin reductase
NP_036151.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012021.2NP_036151.1  peroxiredoxin-5, mitochondrial precursor

    See identical proteins and their annotated locations for NP_036151.1

    Status: PROVISIONAL

    Source sequence(s)
    AC120557
    Consensus CDS
    CCDS29507.1
    UniProtKB/Swiss-Prot
    P99029
    Related
    ENSMUSP00000025904, OTTMUSP00000023383, ENSMUST00000025904, OTTMUST00000050171
    Conserved Domains (1) summary
    cd03013
    Location:54208
    PRX5_like; Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5 ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000085.6 Reference GRCm38.p3 C57BL/6J

    Range
    6906819..6909645 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000041.1 Alternate Mm_Celera

    Range
    6683601..6686426 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)