Format

Send to:

Choose Destination

LRRN3 leucine rich repeat neuronal 3 [ Homo sapiens (human) ]

Gene ID: 54674, updated on 8-May-2016
Official Symbol
LRRN3provided by HGNC
Official Full Name
leucine rich repeat neuronal 3provided by HGNC
Primary source
HGNC:HGNC:17200
See related
Ensembl:ENSG00000173114 HPRD:14321; Vega:OTTHUMG00000155039
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NLRR3; NLRR-3; FIGLER5
Orthologs
Location:
7q31.1
Exon count:
4
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 7 NC_000007.14 (111091006..111125454)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (110731062..110765510)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375452 Neighboring gene uncharacterized LOC105375453 Neighboring gene inner mitochondrial membrane peptidase subunit 2 Neighboring gene argininosuccinate synthase 1 pseudogene Neighboring gene uncharacterized LOC105375455 Neighboring gene dedicator of cytokinesis 4

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ11129

Gene Ontology Provided by GOA

Process Evidence Code Pubs
positive regulation of synapse assembly IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
leucine-rich repeat neuronal protein 3
Names
fibronectin type III, immunoglobulin and leucine rich repeat domains 5
leucine-rich repeat protein, neuronal 3
neuronal leucine-rich repeat protein 3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099658.1NP_001093128.1  leucine-rich repeat neuronal protein 3 precursor

    See identical proteins and their annotated locations for NP_001093128.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AL442092, AY358280, BC035133, DA494543
    Consensus CDS
    CCDS5754.1
    UniProtKB/Swiss-Prot
    Q9H3W5
    UniProtKB/TrEMBL
    A4D0T1
    Related
    ENSP00000312001, OTTHUMP00000207167, ENST00000308478, OTTHUMT00000338172
    Conserved Domains (8) summary
    smart00013
    Location:2872
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:368419
    LRRCT; Leucine rich repeat C-terminal domain
    cd00063
    Location:526593
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:429513
    I-set; Immunoglobulin I-set domain
    pfam12799
    Location:116157
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:93152
    LRR_8; Leucine rich repeat
    sd00033
    Location:94117
    LRR_RI; leucine-rich repeat [structural motif]
    cl11960
    Location:437513
    Ig; Immunoglobulin domain
  2. NM_001099660.1NP_001093130.1  leucine-rich repeat neuronal protein 3 precursor

    See identical proteins and their annotated locations for NP_001093130.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AK001991, AL442092, AY358280, BC035133, DA494543
    Consensus CDS
    CCDS5754.1
    UniProtKB/Swiss-Prot
    Q9H3W5
    UniProtKB/TrEMBL
    A4D0T1, Q9NUU4
    Related
    ENSP00000397312, ENST00000451085
    Conserved Domains (8) summary
    smart00013
    Location:2872
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:368419
    LRRCT; Leucine rich repeat C-terminal domain
    cd00063
    Location:526593
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:429513
    I-set; Immunoglobulin I-set domain
    pfam12799
    Location:116157
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:93152
    LRR_8; Leucine rich repeat
    sd00033
    Location:94117
    LRR_RI; leucine-rich repeat [structural motif]
    cl11960
    Location:437513
    Ig; Immunoglobulin domain
  3. NM_018334.4NP_060804.3  leucine-rich repeat neuronal protein 3 precursor

    See identical proteins and their annotated locations for NP_060804.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AF134481, AL442092, DA494543, DB095402
    Consensus CDS
    CCDS5754.1
    UniProtKB/Swiss-Prot
    Q9H3W5
    UniProtKB/TrEMBL
    A4D0T1
    Related
    ENSP00000412417, OTTHUMP00000207166, ENST00000422987, OTTHUMT00000338171
    Conserved Domains (8) summary
    smart00013
    Location:2872
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:368419
    LRRCT; Leucine rich repeat C-terminal domain
    cd00063
    Location:526593
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:429513
    I-set; Immunoglobulin I-set domain
    pfam12799
    Location:116157
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:93152
    LRR_8; Leucine rich repeat
    sd00033
    Location:94117
    LRR_RI; leucine-rich repeat [structural motif]
    cl11960
    Location:437513
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p2 Primary Assembly

    Range
    111091006..111125454
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018918.2 Alternate CHM1_1.1

    Range
    110664791..110699239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)