- Ascorbate and aldarate metabolism, organism-specific biosystem (from KEGG)
Ascorbate and aldarate metabolism, organism-specific biosystem
Ascorbate and aldarate metabolism
- Ascorbate and aldarate metabolism, conserved biosystem (from KEGG)
Ascorbate and aldarate metabolism, conserved biosystem
Ascorbate and aldarate metabolism
- Ascorbate biosynthesis, animals, glucose-1P => ascorbate, organism-specific biosystem (from KEGG)
Ascorbate biosynthesis, animals, glucose-1P => ascorbate, organism-specific biosystemPathway module; Nucleotide and amino acid metabolism; Cofactor and vitamin biosynthesis
- Ascorbate biosynthesis, animals, glucose-1P => ascorbate, conserved biosystem (from KEGG)
Ascorbate biosynthesis, animals, glucose-1P => ascorbate, conserved biosystemPathway module; Nucleotide and amino acid metabolism; Cofactor and vitamin biosynthesis
- Biological oxidations, organism-specific biosystem (from REACTOME)
Biological oxidations, organism-specific biosystemAll organisms are constantly exposed to foreign chemicals every day. These can be man-made (drugs, industrial chemicals) or natural (alkaloids, toxins from plants and animals). Uptake is usually via ...
- Chemical carcinogenesis, organism-specific biosystem (from KEGG)
Chemical carcinogenesis, organism-specific biosystemIt has been estimated that exposure to environmental chemical carcinogens may contribute significantly to the causation of a sizable fraction, perhaps a majority, of human cancers. Human carcinogens ...
- Chemical carcinogenesis, conserved biosystem (from KEGG)
Chemical carcinogenesis, conserved biosystemIt has been estimated that exposure to environmental chemical carcinogens may contribute significantly to the causation of a sizable fraction, perhaps a majority, of human cancers. Human carcinogens ...
- Drug metabolism - cytochrome P450, organism-specific biosystem (from KEGG)
Drug metabolism - cytochrome P450, organism-specific biosystem
Drug metabolism - cytochrome P450
- Drug metabolism - cytochrome P450, conserved biosystem (from KEGG)
Drug metabolism - cytochrome P450, conserved biosystem
Drug metabolism - cytochrome P450
- Drug metabolism - other enzymes, organism-specific biosystem (from KEGG)
Drug metabolism - other enzymes, organism-specific biosystem
Drug metabolism - other enzymes
- Drug metabolism - other enzymes, conserved biosystem (from KEGG)
Drug metabolism - other enzymes, conserved biosystem
Drug metabolism - other enzymes
- Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem (from REACTOME)
Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystemThe reactions involved in the metabolism of fatty acids and of the triacylglycerols and ketone bodies derived from them form a closely interrelated, coordinately regulated module that plays a central...
- Glucuronidation, organism-specific biosystem (from WikiPathways)
Glucuronidation, organism-specific biosystemMetabolism of xenobiotic compounds consists of phase I and a phase II biotransformation reactions, being compound modification and conjugation reactions respectively. In phase I biotransformation, th...
- Glucuronidation, organism-specific biosystem (from REACTOME)
Glucuronidation, organism-specific biosystemGlucuronidation conjugation utilizes UDP-glucuronosyltransferases (UGTs; EC 2.4.1.17) to catalyze a wide range of diverse endogenous and xenobiotic compounds. Glucuronidation is the major pathway in ...
- Heme degradation, organism-specific biosystem (from REACTOME)
Heme degradation, organism-specific biosystemMost of the heme degraded in humans comes from hemoglobin. Approximately 6-8 grams of hemoglobin is degraded daily which is equivalent to approximately 300 milligrams of heme per day. Heme is not rec...
- Irinotecan Pathway, organism-specific biosystem (from WikiPathways)
Irinotecan Pathway, organism-specific biosystemThis pathway shows the biotransformation of the chemotherapy prodrug irinotecan to form the active metabolite SN-38, an inhibitor of DNA topoisomerase I. SN-38 is primarily metabolized to the inactiv...
- Metabolism, organism-specific biosystem (from REACTOME)
Metabolism, organism-specific biosystemMetabolic processes in human cells generate energy through the oxidation of molecules consumed in the diet and mediate the synthesis of diverse essential molecules not taken in the diet as well as th...
- Metabolism of lipids and lipoproteins, organism-specific biosystem (from REACTOME)
Metabolism of lipids and lipoproteins, organism-specific biosystemLipids are hydrophobic but otherwise chemically diverse molecules that play a wide variety of roles in human biology. They include ketone bodies, fatty acids, triacylglycerols, phospholipids and sphi...
- Metabolism of porphyrins, organism-specific biosystem (from REACTOME)
Metabolism of porphyrins, organism-specific biosystemPorphyrins are heterocyclic macrocycles, consisting of four pyrrole subunits (tetrapyrrole) linked by four methine (=CH-) bridges. The extensive conjugated porphyrin macrocycle is chromatic and the n...
- Metabolism of xenobiotics by cytochrome P450, organism-specific biosystem (from KEGG)
Metabolism of xenobiotics by cytochrome P450, organism-specific biosystem
Metabolism of xenobiotics by cytochrome P450
- Metabolism of xenobiotics by cytochrome P450, conserved biosystem (from KEGG)
Metabolism of xenobiotics by cytochrome P450, conserved biosystem
Metabolism of xenobiotics by cytochrome P450
- PPARA Activates Gene Expression, organism-specific biosystem (from REACTOME)
PPARA Activates Gene Expression, organism-specific biosystemThe set of genes regulated by PPAR-alpha is not fully known in humans, however many examples have been found in mice. Genes directly activated by PPAR-alpha contain peroxisome proliferator receptor e...
- Pentose and glucuronate interconversions, organism-specific biosystem (from KEGG)
Pentose and glucuronate interconversions, organism-specific biosystem
Pentose and glucuronate interconversions
- Pentose and glucuronate interconversions, conserved biosystem (from KEGG)
Pentose and glucuronate interconversions, conserved biosystem
Pentose and glucuronate interconversions
- Phase II conjugation, organism-specific biosystem (from REACTOME)
Phase II conjugation, organism-specific biosystemPhase II of biotransformation is concerned with conjugation, that is using groups from cofactors to react with functional groups present or introduced from phase I on the compound. The enzymes involv...
- Porphyrin and chlorophyll metabolism, organism-specific biosystem (from KEGG)
Porphyrin and chlorophyll metabolism, organism-specific biosystem
Porphyrin and chlorophyll metabolism
- Porphyrin and chlorophyll metabolism, conserved biosystem (from KEGG)
Porphyrin and chlorophyll metabolism, conserved biosystem
Porphyrin and chlorophyll metabolism
- Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha), organism-specific biosystem (from REACTOME)
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha), organism-specific biosystemPeroxisome proliferator-activated receptor alpha (PPAR-alpha) is the major regulator of fatty acid oxidation in the liver. PPARalpha is also the target of fibrate drugs used to treat abnormal plasma ...
- Retinol metabolism, organism-specific biosystem (from KEGG)
Retinol metabolism, organism-specific biosystem
Retinol metabolism
- Retinol metabolism, conserved biosystem (from KEGG)
Retinol metabolism, conserved biosystem
Retinol metabolism
- Starch and sucrose metabolism, organism-specific biosystem (from KEGG)
Starch and sucrose metabolism, organism-specific biosystem
Starch and sucrose metabolism
- Starch and sucrose metabolism, conserved biosystem (from KEGG)
Starch and sucrose metabolism, conserved biosystem
Starch and sucrose metabolism
- Steroid hormone biosynthesis, organism-specific biosystem (from KEGG)
Steroid hormone biosynthesis, organism-specific biosystemSteroid hormones derived from cholesterol are a class of biologically active compounds in vertebrates. The cholesterol side-chain cleavage enzyme CYP11A1 catalyzes conversion of cholesterol, a C27 co...
- Steroid hormone biosynthesis, conserved biosystem (from KEGG)
Steroid hormone biosynthesis, conserved biosystemSteroid hormones derived from cholesterol are a class of biologically active compounds in vertebrates. The cholesterol side-chain cleavage enzyme CYP11A1 catalyzes conversion of cholesterol, a C27 co...
- Tamoxifen metabolism, organism-specific biosystem (from WikiPathways)
Tamoxifen metabolism, organism-specific biosystem
Tamoxifen metabolism
- melatonin degradation I, organism-specific biosystem (from BIOCYC)
melatonin degradation I, organism-specific biosystemGeneral Background The indoleamine : N-ACETYL-5-METHOXY-TRYPTAMINE is a vertebrate hormone secreted by the pineal gland. It is involved in regulation of circadian and seasonal rhythms. : N-ACETYL-...
- metapathway biotransformation, organism-specific biosystem (from WikiPathways)
metapathway biotransformation, organism-specific biosystem
metapathway biotransformation
- nicotine degradation III, organism-specific biosystem (from BIOCYC)
nicotine degradation III, organism-specific biosystemNicotine is the principal alkaloid in the leaves of commercially used tobacco (Nicotiana tabacum and N. rustica) . Nicotine in tobacco leaves and in plant-derived preparations is mostly in the (S)...
- nicotine degradation IV, organism-specific biosystem (from BIOCYC)
nicotine degradation IV, organism-specific biosystemNicotine is the principal alkaloid in the leaves of commercially used tobacco (Nicotiana tabacum and N. rustica) . Nicotine in tobacco leaves and in plant-derived preparations is mostly in the (S)...
- serotonin degradation, organism-specific biosystem (from BIOCYC)
serotonin degradation, organism-specific biosystemGeneral Background The neurotransmitter and neuromodulator : SEROTONIN has important roles in the mammalian central nervous system including learning, memory and development. Imbalance of : SEROTON...
- superpathway of melatonin degradation, organism-specific biosystem (from BIOCYC)
superpathway of melatonin degradation, organism-specific biosystem
superpathway of melatonin degradation
- thyroid hormone metabolism II (via conjugation and/or degradation), organism-specific biosystem (from BIOCYC)
thyroid hormone metabolism II (via conjugation and/or degradation), organism-specific biosystemGeneral Background The thyroid hormones : L-THYROXINE (T4) and : LIOTHYRONINE (T3) are essential for normal vertebrate metabolism, growth and development. These : CPD-387-containing molecules are b...