These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_001198783.1 → NP_001185712.1 POU domain, class 2, transcription factor 1 isoform 2
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) has an alternate 5' exon, as compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus, as compared to isoform 1.
- Source sequence(s)
-
AL136984, AL359962, BC001664, DA937884
- Consensus CDS
-
CCDS55656.1
- UniProtKB/Swiss-Prot
-
P14859
- Related
- ENSP00000356836, OTTHUMP00000032349, ENST00000367862, OTTHUMT00000083248
- Conserved Domains (2) summary
-
- cd00086
Location:392 – 448
Blast Score: 167
- homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
- cl02582
Location:302 – 361
Blast Score: 326
- Pou; Pou domain - N-terminal to homeobox domain
-
NM_001198786.1 → NP_001185715.1 POU domain, class 2, transcription factor 1 isoform 3
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) lacks an in-frame coding exon, as compared to variant 3. The resulting isoform (3) lacks an internal segment, as compared to isoform 1.
- Source sequence(s)
-
AK303201, AL136984, AL359962, BX954888
- Consensus CDS
-
CCDS55655.1
- Related
- ENSP00000401217, OTTHUMP00000247264, ENST00000429375, OTTHUMT00000416073
- Conserved Domains (2) summary
-
- cd00086
Location:340 – 396
Blast Score: 166
- homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
- cl02582
Location:250 – 309
Blast Score: 325
- Pou; Pou domain - N-terminal to homeobox domain
-
NM_002697.3 → NP_002688.3 POU domain, class 2, transcription factor 1 isoform 1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AL136984, AL359962, BC001664, BX954888, X13403
- Consensus CDS
-
CCDS1259.2
- UniProtKB/Swiss-Prot
-
P14859
- Related
- ENSP00000356840, OTTHUMP00000032348, ENST00000367866, OTTHUMT00000083247
- Conserved Domains (2) summary
-
- cd00086
Location:403 – 459
Blast Score: 165
- homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
- cl02582
Location:313 – 372
Blast Score: 325
- Pou; Pou domain - N-terminal to homeobox domain
RNA
-
NR_037163.1 RNA Sequence
- Description
- Transcript Variant: This variant (4) has an additional exon in the 5' region, which results in an internal stop codon, as compared to variant 1. The transcript is a nonsense-mediated mRNA decay candidate and will not make a functional protein.
- Source sequence(s)
-
AL136984, AL359962, BC052274, DC370634
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000001.10 Reference GRCh37.p5 Primary Assembly
- Range
- 167190066..167396582
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000133.1 Alternate HuRef
- Range
- 138436084..138642676
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)