Format

Send to:

Choose Destination

TAF7L TATA-box binding protein associated factor 7 like [ Homo sapiens (human) ]

Gene ID: 54457, updated on 8-May-2016
Official Symbol
TAF7Lprovided by HGNC
Official Full Name
TATA-box binding protein associated factor 7 likeprovided by HGNC
Primary source
HGNC:HGNC:11548
See related
Ensembl:ENSG00000102387 HPRD:02259; MIM:300314; Vega:OTTHUMG00000022021
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT40; TAF2Q
Summary
This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Orthologs
Location:
Xq22.1
Exon count:
14
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) X NC_000023.11 (101268253..101293071, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (100523241..100548059, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene YWHAQ pseudogene 8 Neighboring gene dystrophin related protein 2 Neighboring gene NANOGNB pseudogene 3 Neighboring gene ribosomal protein L21 pseudogene 132

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ23157

Gene Ontology Provided by GOA

Function Evidence Code Pubs
histone acetyltransferase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
molecular_function ND
No biological Data available
more info
 
transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
transcription regulatory region DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
RNA polymerase II transcriptional preinitiation complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
biological_process ND
No biological Data available
more info
 
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription from RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
 
spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
transcription factor TFIID complex IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
transcription initiation factor TFIID subunit 7-like
Names
RNA polymerase II TBP-associated factor subunit Q
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
TATA box binding protein associated factor 7 like
TATA box-binding protein-associated factor 50 kDa
TBP-associated factor, RNA polymerase II, Q
cancer/testis antigen 40
transcription initiation factor TFIID 50 kDa subunit

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016220.1 RefSeqGene

    Range
    5001..29819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001168474.1NP_001161946.1  transcription initiation factor TFIID subunit 7-like isoform 2

    See identical proteins and their annotated locations for NP_001161946.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AF285595, BC043391, DB042169
    Consensus CDS
    CCDS55466.1
    UniProtKB/Swiss-Prot
    Q5H9L4
    Related
    ENSP00000349235, OTTHUMP00000023674, ENST00000356784, OTTHUMT00000057525
    Conserved Domains (1) summary
    cd08047
    Location:13197
    TAF7; TATA Binding Protein (TBP) Associated Factor 7 (TAF7) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
  2. NM_024885.3NP_079161.3  transcription initiation factor TFIID subunit 7-like isoform 1

    See identical proteins and their annotated locations for NP_079161.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AL109801, BC043391, DB455298
    Consensus CDS
    CCDS35347.1
    UniProtKB/Swiss-Prot
    Q5H9L4
    Related
    ENSP00000361998, OTTHUMP00000023675, ENST00000372907, OTTHUMT00000057526
    Conserved Domains (1) summary
    cd08047
    Location:99283
    TAF7; TATA Binding Protein (TBP) Associated Factor 7 (TAF7) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p2 Primary Assembly

    Range
    101268253..101293071 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005262151.1XP_005262208.1  

    Conserved Domains (1) summary
    cd08047
    Location:99283
    TAF7; TATA Binding Protein (TBP) Associated Factor 7 (TAF7) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
  2. XM_006724664.1XP_006724727.1  

    Conserved Domains (1) summary
    cd08047
    Location:99283
    TAF7; TATA Binding Protein (TBP) Associated Factor 7 (TAF7) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
  3. XM_005262152.1XP_005262209.1  

    See identical proteins and their annotated locations for XP_005262209.1

    Conserved Domains (1) summary
    cd08047
    Location:13197
    TAF7; TATA Binding Protein (TBP) Associated Factor 7 (TAF7) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

Alternate CHM1_1.1

Genomic

  1. NC_018934.2 Alternate CHM1_1.1

    Range
    100417044..100441569 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)