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CYTL1 cytokine like 1 [ Homo sapiens (human) ]

Gene ID: 54360, updated on 7-May-2016
Official Symbol
CYTL1provided by HGNC
Official Full Name
cytokine like 1provided by HGNC
Primary source
HGNC:HGNC:24435
See related
Ensembl:ENSG00000170891 HPRD:16260; MIM:607930; Vega:OTTHUMG00000125479
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C17; C4orf4
Summary
C17 is a cytokine-like protein specifically expressed in bone marrow and cord blood mononuclear cells that bear the CD34 (MIM 142230) surface marker (Liu et al., 2000 [PubMed 10857752]).[supplied by OMIM, Mar 2008]
Orthologs
Location:
4p16-p15
Exon count:
4
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 4 NC_000004.12 (5014586..5019470, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (5016313..5021197, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928306 Neighboring gene lactate dehydrogenase A pseudogene 1 Neighboring gene uncharacterized LOC105374361 Neighboring gene serine/threonine kinase 32B Neighboring gene uncharacterized LOC105374362 Neighboring gene long intergenic non-protein coding RNA 1587

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
receptor binding TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
cartilage homeostasis IEA
Inferred from Electronic Annotation
more info
 
chondrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
chondroitin sulfate proteoglycan biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
inner ear development IEA
Inferred from Electronic Annotation
more info
 
positive regulation of sequence-specific DNA binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
signal transduction TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
extracellular space TAS
Traceable Author Statement
more info
PubMed 
Preferred Names
cytokine-like protein 1
Names
cytokine-like 1
cytokine-like protein C17

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018659.2NP_061129.1  cytokine-like protein 1 precursor

    See identical proteins and their annotated locations for NP_061129.1

    Status: VALIDATED

    Source sequence(s)
    AY359101, BC031391, T83161
    Consensus CDS
    CCDS3379.1
    UniProtKB/Swiss-Prot
    Q9NRR1
    Related
    ENSP00000303550, OTTHUMP00000155130, ENST00000307746, OTTHUMT00000246802
    Conserved Domains (1) summary
    pfam15153
    Location:21136
    CYTL1; Cytokine-like protein 1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p2 Primary Assembly

    Range
    5014586..5019470 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018915.2 Alternate CHM1_1.1

    Range
    5014307..5019195 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)