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PAK6 p21 (RAC1) activated kinase 6 [ Bos taurus (cattle) ]

Gene ID: 539224, updated on 5-Mar-2024

Summary

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Gene symbol
PAK6
Gene description
p21 (RAC1) activated kinase 6
See related
BGD:BT24613; Ensembl:ENSBTAG00000019076
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (35856089..35895687)

Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene BUB1 mitotic checkpoint serine/threonine kinase B Neighboring gene transfer RNA serine (anticodon AGA) Neighboring gene uncharacterized LOC101905672 Neighboring gene ankyrin repeat domain 63 Neighboring gene phospholipase C beta 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 6
Names
p21(CDKN1A)-activated kinase 6
NP_001179127.1
XP_005211647.1
XP_010807496.1
XP_010807497.1
XP_010807498.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192198.1 → NP_001179127.1  serine/threonine-protein kinase PAK 6

    See identical proteins and their annotated locations for NP_001179127.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000010
    UniProtKB/TrEMBL
    E1BA03
    Related
    ENSBTAP00000025396.5, ENSBTAT00000025396.6
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 67
    PBD; P21-Rho-binding domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    35856089..35895687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010809194.4 → XP_010807496.1  serine/threonine-protein kinase PAK 6 isoform X1

    See identical proteins and their annotated locations for XP_010807496.1

    UniProtKB/TrEMBL
    E1BA03
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 67
    PBD; P21-Rho-binding domain

  2. XM_010809195.4 → XP_010807497.1  serine/threonine-protein kinase PAK 6 isoform X1

    See identical proteins and their annotated locations for XP_010807497.1

    UniProtKB/TrEMBL
    E1BA03
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 67
    PBD; P21-Rho-binding domain

  3. XM_010809196.4 → XP_010807498.1  serine/threonine-protein kinase PAK 6 isoform X1

    See identical proteins and their annotated locations for XP_010807498.1

    UniProtKB/TrEMBL
    E1BA03
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 67
    PBD; P21-Rho-binding domain

  4. XM_005211590.5 → XP_005211647.1  serine/threonine-protein kinase PAK 6 isoform X1

    See identical proteins and their annotated locations for XP_005211647.1

    UniProtKB/TrEMBL
    E1BA03
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 67
    PBD; P21-Rho-binding domain
Nucleotide Protein Strain
Heading Accession and Version

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