These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_001003827.1 → NP_001003827.1 tripartite motif-containing protein 34 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Both variants 1 and 4 encode the same isoform (1, also known as the middle form).
- Source sequence(s)
-
AB039902, AF220144, BM989990
- Consensus CDS
-
CCDS31391.1
- UniProtKB/Swiss-Prot
-
Q9BYJ4
- Related
- ENSP00000422947, OTTHUMP00000069810, ENST00000514226, OTTHUMT00000143357
- Conserved Domains (4) summary
-
- cd00021
Location:95 – 132
Blast Score: 103
- BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
- pfam13923
Location:11 – 59
Blast Score: 99
- zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)
- cl02614
Location:346 – 486
Blast Score: 225
- SPRY; SPRY domain
- cl15348
Location:15 – 59
Blast Score: 99
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
-
NM_021616.5 → NP_067629.2 tripartite motif-containing protein 34 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1, also known as alpha) represents the longest transcript and encodes the longer isoform (1, also known as the middle form). Both variants 1 and 4 encode the same isoform.
- Source sequence(s)
-
AF220143, BG682537, DB024660
- Consensus CDS
-
CCDS31391.1
- UniProtKB/Swiss-Prot
-
Q9BYJ4
- Related
- ENSP00000402595, OTTHUMP00000069809, ENST00000429814, OTTHUMT00000143355
- Conserved Domains (4) summary
-
- cd00021
Location:95 – 132
Blast Score: 103
- BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
- pfam13923
Location:11 – 59
Blast Score: 99
- zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)
- cl02614
Location:346 – 486
Blast Score: 225
- SPRY; SPRY domain
- cl15348
Location:15 – 59
Blast Score: 99
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
-
NM_130390.2 → NP_569074.2 tripartite motif-containing protein 34 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks several 3' exons but includes a unique segment at its 3' end, compared to variant 1. The encoded isoform (3, also known as the short form) has a distinct and shorter C-terminus, compared to isoform 1. The 5' UTR is incomplete due to a lack of 5'-complete transcripts representing this variant and the presence of splicing ambiguity in the 5' region.
- Source sequence(s)
-
AB039902, DA847894
- UniProtKB/Swiss-Prot
-
Q9BYJ4
- Conserved Domains (3) summary
-
- pfam13923
Location:11 – 59
Blast Score: 93
- zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)
- cl00034
Location:92 – 132
Blast Score: 100
- BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
- cl15348
Location:15 – 59
Blast Score: 94
- RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000011.9 Reference GRCh37.p5 Primary Assembly
- Range
- 5641174..5665628
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000143.1 Alternate HuRef
- Range
- 5300832..5325294
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the cited
reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links,
or BLAST links (BLink), but may still be retrieved by clicking on their
accession.version below.
-
NM_130389.3: Suppressed sequence
- Description
- NM_130389.3: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.