These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_001145319.1 → NP_001138791.1 plastin-1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the more predominant transcript. Transcript variants 1, 2 and 3 encode the same protein.
- Source sequence(s)
-
AA933088, AK290316, BM263745, DA427212, L20826
- Consensus CDS
-
CCDS3125.1
- UniProtKB/Swiss-Prot
-
Q14651
- Related
- ENSP00000387890, OTTHUMP00000214728, ENST00000457734, OTTHUMT00000354434
- Conserved Domains (4) summary
-
- cd00014
Location:123 – 238
Blast Score: 214
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00051
Location:15 – 81
Blast Score: 155
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- COG5069
Location:13 – 621
Blast Score: 624
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cl00030
Location:399 – 502
Blast Score: 172
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
-
NM_001172312.1 → NP_001165783.1 plastin-1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) contains an alternate 5' terminal non-coding exon, thus has a different 5' UTR compared to variant 1. Transcript variants 1, 2 and 3 encode the same protein.
- Source sequence(s)
-
AC072028, BC031083, CB240816
- Consensus CDS
-
CCDS3125.1
- UniProtKB/Swiss-Prot
-
Q14651
- Related
- ENSP00000418700, OTTHUMP00000214730, ENST00000497002, OTTHUMT00000354436
- Conserved Domains (4) summary
-
- cd00014
Location:123 – 238
Blast Score: 214
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00051
Location:15 – 81
Blast Score: 155
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- COG5069
Location:13 – 621
Blast Score: 624
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cl00030
Location:399 – 502
Blast Score: 172
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
-
NM_002670.2 → NP_002661.2 plastin-1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) contains an alternate 5' terminal non-coding exon, thus has a different 5' UTR compared to variant 1. Transcript variants 1, 2 and 3 encode the same protein.
- Source sequence(s)
-
AA933088, AK290316, BM263745, BP262012, L20826
- Consensus CDS
-
CCDS3125.1
- UniProtKB/Swiss-Prot
-
Q14651
- Related
- ENSP00000336831, OTTHUMP00000214729, ENST00000337777, OTTHUMT00000354435
- Conserved Domains (4) summary
-
- cd00014
Location:123 – 238
Blast Score: 214
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00051
Location:15 – 81
Blast Score: 155
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- COG5069
Location:13 – 621
Blast Score: 624
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cl00030
Location:399 – 502
Blast Score: 172
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000003.11 Reference GRCh37.p5 Primary Assembly
- Range
- 142315229..142432506
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000135.1 Alternate HuRef
- Range
- 139687922..139805221
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)