These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_029750.1 RefSeqGene
- Range
- 5001..48820
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001001895.2 → NP_001001895.1 ubiquitin-associated and SH3 domain-containing protein A isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (2, also known as short form) that is shorter than isoform 1.
- Source sequence(s)
-
AA707211, AF521702, AJ277750, DA926085
- Consensus CDS
-
CCDS33566.1
- UniProtKB/Swiss-Prot
-
P57075
- Related
- ENSP00000291535, OTTHUMP00000109367, ENST00000291535, OTTHUMT00000195383
- Conserved Domains (3) summary
-
- cd00174
Location:242 – 298
Blast Score: 122
- SH3; Src homology 3 domains; SH3 domains bind to proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs; they play a role in the regulation of enzymes by intramolecular interactions, changing the subcellular localization of ...
- COG5207
Location:30 – 70
Blast Score: 111
- UBP14; Isopeptidase T [Posttranslational modification, protein turnover, chaperones]
- cd07067
Location:360 – 572
Blast Score: 148
- HP_PGM_like; Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction.
-
NM_001243467.1 → NP_001230396.1 ubiquitin-associated and SH3 domain-containing protein A isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, and two alternate exons that result in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.
- Source sequence(s)
-
AA707211, AJ277750, AP001624, BC069577, DA926085
- UniProtKB/TrEMBL
-
G5E9E4
- UniProtKB/Swiss-Prot
-
P57075
- Conserved Domains (4) summary
-
- cd00174
Location:242 – 298
Blast Score: 121
- SH3; Src homology 3 domains; SH3 domains bind to proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs; they play a role in the regulation of enzymes by intramolecular interactions, changing the subcellular localization of ...
- COG5207
Location:30 – 70
Blast Score: 111
- UBP14; Isopeptidase T [Posttranslational modification, protein turnover, chaperones]
- cd07067
Location:360 – 452
Blast Score: 132
- HP_PGM_like; Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction.
- cl11399
Location:412 – 511
Blast Score: 116
- HP; Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction.
-
NM_018961.3 → NP_061834.1 ubiquitin-associated and SH3 domain-containing protein A isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1, also known as long form).
- Source sequence(s)
-
AA707211, AJ277750, DA926085
- Consensus CDS
-
CCDS13687.1
- UniProtKB/Swiss-Prot
-
P57075
- Related
- ENSP00000317327, OTTHUMP00000109366, ENST00000319294, OTTHUMT00000195382
- Conserved Domains (3) summary
-
- cd00174
Location:280 – 336
Blast Score: 122
- SH3; Src homology 3 domains; SH3 domains bind to proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs; they play a role in the regulation of enzymes by intramolecular interactions, changing the subcellular localization of ...
- COG5207
Location:30 – 70
Blast Score: 111
- UBP14; Isopeptidase T [Posttranslational modification, protein turnover, chaperones]
- cd07067
Location:398 – 610
Blast Score: 148
- HP_PGM_like; Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction.
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000021.8 Reference GRCh37.p5 Primary Assembly
- Range
- 43824019..43867774
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000153.1 Alternate HuRef
- Range
- 29241580..29247337
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)