DSG3 desmoglein 3 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: DSG3provided by VGNC
Official Full Name: desmoglein 3provided by VGNC
Primary source: VGNC:VGNC:28222
See related: Ensembl:ENSBTAG00000039483
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 24

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	24	NC_037351.1 (25667567..25698964, complement)

Chromosome 24 - NC_037351.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in homophilic cell adhesion via plasma membrane adhesion molecules	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in desmosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: desmoglein-3

Names: desmoglein 3 (pemphigus vulgaris antigen)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001192685.1 → NP_001179614.1 desmoglein-3 precursor

See identical proteins and their annotated locations for NP_001179614.1

Status: PROVISIONAL

Source sequence(s)

NKLS02000024

UniProtKB/TrEMBL

E1BM91

Related

ENSBTAP00000002538.4, ENSBTAT00000002538.6

Conserved Domains (4) summary

cd11304
Location:160 → 262

Cadherin_repeat; Cadherin tandem repeat domain

smart00112
Location:74 → 154

CA; Cadherin repeats

pfam00028
Location:271 → 374

Cadherin; Cadherin domain

pfam01049
Location:788 → 846

Cadherin_C; Cadherin cytoplasmic region