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SUPT5H SPT5 homolog, DSIF elongation factor subunit [ Bos taurus (cattle) ]

Gene ID: 519808, updated on 5-Mar-2024

Summary

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Official Symbol
SUPT5Hprovided by VGNC
Official Full Name
SPT5 homolog, DSIF elongation factor subunitprovided by VGNC
Primary source
VGNC:VGNC:35481
See related
Ensembl:ENSBTAG00000010467
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (49132480..49159093)

Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S16 Neighboring gene interleukin 15-like Neighboring gene translocase of inner mitochondrial membrane 50 Neighboring gene delta like canonical Notch ligand 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC142813

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transcription elongation-coupled chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of DSIF complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription elongation factor SPT5
Names
suppressor of Ty 5 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083439.2 → NP_001076908.2  transcription elongation factor SPT5

    See identical proteins and their annotated locations for NP_001076908.2

    Status: PROVISIONAL

    Source sequence(s)
    BC134446
    UniProtKB/TrEMBL
    A7YW40
    Related
    ENSBTAP00000041740.4, ENSBTAT00000044229.4
    Conserved Domains (12) summary
    PRK08559
    Location:171 → 312
    nusG; transcription antitermination protein NusG; Validated
    cd09888
    Location:174 → 261
    NGN_Euk; Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW domain-containing Transcription Factor 1)
    COG5164
    Location:330 → 961
    SPT5; Transcription elongation factor [Transcription]
    cd06081
    Location:272 → 309
    KOW_Spt5_1; KOW domain of Spt5, repeat 1
    cd06082
    Location:416 → 466
    KOW_Spt5_2; KOW domain of Spt5, repeat 2
    cd06083
    Location:467 → 517
    KOW_Spt5_3; KOW domain of Spt5, repeat 3
    cd06084
    Location:593 → 635
    KOW_Spt5_4; KOW domain of Spt5, repeat 4
    cd06085
    Location:698 → 747
    KOW_Spt5_5; KOW domain of Spt5, repeat 5
    cd06086
    Location:1024 → 1080
    KOW_Spt5_6; KOW domain of Spt5, repeat 6
    pfam04731
    Location:843 → 972
    Caudal_act; Caudal like protein activation region
    pfam11942
    Location:75 → 167
    Spt5_N; Spt5 transcription elongation factor, acidic N-terminal
    pfam12815
    Location:762 → 818
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    49132480..49159093
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059876733.1 → XP_059732716.1  transcription elongation factor SPT5 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MQ76

  2. XM_024978257.2 → XP_024834025.1  transcription elongation factor SPT5 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MQ76
    Conserved Domains (5) summary
    cd09888
    Location:178 → 265
    NGN_Euk; Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW domain-containing Transcription Factor 1)
    cd06081
    Location:276 → 313
    KOW_Spt5_1; KOW domain of Spt5, repeat 1
    cd06086
    Location:1028 → 1084
    KOW_Spt5_6; KOW domain of Spt5, repeat 6
    pfam11942
    Location:75 → 171
    Spt5_N; Spt5 transcription elongation factor, acidic N-terminal
    cl26303
    Location:334 → 965
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4

  3. XM_024978256.2 → XP_024834024.1  transcription elongation factor SPT5 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MQ76
    Related
    ENSBTAP00000071865.2, ENSBTAT00000070366.2
    Conserved Domains (5) summary
    cd09888
    Location:178 → 265
    NGN_Euk; Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW domain-containing Transcription Factor 1)
    cd06081
    Location:276 → 313
    KOW_Spt5_1; KOW domain of Spt5, repeat 1
    cd06086
    Location:1028 → 1084
    KOW_Spt5_6; KOW domain of Spt5, repeat 6
    pfam11942
    Location:75 → 171
    Spt5_N; Spt5 transcription elongation factor, acidic N-terminal
    cl26303
    Location:334 → 965
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4

  4. XM_059876734.1 → XP_059732717.1  transcription elongation factor SPT5 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

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