SOX18 SRY-box transcription factor 18 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: SOX18provided by VGNC
Official Full Name: SRY-box transcription factor 18provided by VGNC
Primary source: VGNC:VGNC:35145
See related: Ensembl:ENSBTAG00000011662
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	13	NC_037340.1 (53823431..53825287)

Chromosome 13 - NC_037340.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in angiogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in lymphangiogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in vasculogenesis	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: transcription factor SOX-18

Names: SRY (sex determining region Y)-box 18; SRY-box 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001075789.1 → NP_001069257.1 transcription factor SOX-18

See identical proteins and their annotated locations for NP_001069257.1

Status: PROVISIONAL

Source sequence(s)

BC120384

UniProtKB/TrEMBL

F6RRS7, Q0VC26

Related

ENSBTAP00000015485.5, ENSBTAT00000015485.5

Conserved Domains (2) summary

cd01388
Location:84 → 155

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...

pfam12067
Location:195 → 387

Sox_C_TAD; Sox C-terminal transactivation domain