Format

Send to:

Choose Destination

CYB5R1 cytochrome b5 reductase 1 [ Homo sapiens (human) ]

Gene ID: 51706, updated on 26-May-2016
Official Symbol
CYB5R1provided by HGNC
Official Full Name
cytochrome b5 reductase 1provided by HGNC
Primary source
HGNC:HGNC:13397
See related
Ensembl:ENSG00000159348 HPRD:06434; MIM:608341; Vega:OTTHUMG00000041387
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
B5R1; B5R2; B5R.1; NQO3A2; humb5R2
Orthologs
Location:
1q32.1
Exon count:
9
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 1 NC_000001.11 (202961873..202967276, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (202931001..202936404, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene kelch like family member 12 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene 59 Neighboring gene adiponectin receptor 1 Neighboring gene alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515 homolog Neighboring gene ribosomal protein S20 pseudogene 8 Neighboring gene transmembrane protein 183A

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
cytochrome-b5 reductase activity, acting on NAD(P)H TAS
Traceable Author Statement
more info
 
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
bicarbonate transport TAS
Traceable Author Statement
more info
 
biological_process ND
No biological Data available
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
platelet degranulation TAS
Traceable Author Statement
more info
 
positive regulation of protein targeting to mitochondrion IMP
Inferred from Mutant Phenotype
more info
PubMed 
sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
 
extracellular exosome IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
platelet alpha granule membrane TAS
Traceable Author Statement
more info
 
Preferred Names
NADH-cytochrome b5 reductase 1
Names
NAD(P)H:quinone oxidoreductase type 3, polypeptide A2
NP_057327.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016243.2NP_057327.2  NADH-cytochrome b5 reductase 1

    See identical proteins and their annotated locations for NP_057327.2

    Status: VALIDATED

    Source sequence(s)
    AY359026, BC018732
    Consensus CDS
    CCDS1431.1
    UniProtKB/Swiss-Prot
    Q9UHQ9
    Related
    ENSP00000356218, OTTHUMP00000038802, ENST00000367249, OTTHUMT00000099155
    Conserved Domains (2) summary
    cd06183
    Location:49305
    cyt_b5_reduct_like; Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a ...
    PTZ00319
    Location:15305
    PTZ00319; NADH-cytochrome B5 reductase; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p2 Primary Assembly

    Range
    202961873..202967276 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 Alternate CHM1_1.1

    Range
    204353240..204358642 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)