GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) [Homo sapiens] - Gene

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Summary

Official Symbol: GET4provided by HGNC
Official Full Name: golgi to ER traffic protein 4 homolog (S. cerevisiae)provided by HGNC
Primary source: HGNC:21690
Locus tag: CGI-20
See related: Ensembl:ENSG00000239857; HPRD:12909; MIM:612056; Vega:OTTHUMG00000112459
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: CEE; TRC35; CGI-20; C7orf20

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Genomic context

Location :: 7p22.3

Sequence :: Chromosome: 7; NC_000007.13 (916191..936071)

See GET4 in Epigenomics, MapViewer

Chromosome 7 - NC_000007.13 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

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Products	Interactant	Other Gene	Source	Pubs	Description
Q7L5D6	O75947	ATP5H	HPRD	PubMed
Q7L5D6	Hypothetical protein MGC40107	C17orf61	HPRD	PubMed
Q7L5D6	P04632	CAPNS1	HPRD	PubMed
Q7L5D6	P38936	CDKN1A	HPRD	PubMed
Q7L5D6	P26641	EEF1G	HPRD	PubMed
Q7L5D6	Q92993	KAT5	HPRD	PubMed
Q7L5D6	Q9P2H0	KIAA1377	HPRD	PubMed
Q7L5D6	Q96AC6	KIFC2	HPRD	PubMed
Q7L5D6	P53350	PLK1	HPRD	PubMed
Q7L5D6	P14314	PRKCSH	HPRD	PubMed
Q7L5D6	P20962	PTMS	HPRD	PubMed
Q7L5D6	Q9Y6H5	SNCAIP	HPRD	PubMed
Q7L5D6	P04179	SOD2	HPRD	PubMed
Q7L5D6	P02766	TTR	HPRD	PubMed
Q7L5D6	Phosphoglycerate dehydrogenase like 1	UBAC2	HPRD	PubMed
BioGRID:119636	BioGRID:107276	CAPNS1	BioGRID	PubMed	Two-hybrid
BioGRID:119636	BioGRID:107460	CDKN1A	BioGRID	PubMed	Two-hybrid
BioGRID:119636	BioGRID:108257	EEF1G	BioGRID	PubMed	Two-hybrid
BioGRID:119636	BioGRID:115779	KAT5	BioGRID	PubMed	Two-hybrid
BioGRID:119636	BioGRID:115156	KEAP1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:119636	BioGRID:121617	KIAA1377	BioGRID	PubMed	Two-hybrid
BioGRID:119636	BioGRID:111362	PLK1	BioGRID	PubMed	Two-hybrid
BioGRID:119636	BioGRID:111575	PRKCSH	BioGRID	PubMed	Two-hybrid
BioGRID:119636	BioGRID:114986	SNCAIP	BioGRID	PubMed	Two-hybrid
BioGRID:119636	BioGRID:113127	TTR	BioGRID	PubMed	Two-hybrid
BioGRID:119636	BioGRID:113164	UBC	BioGRID	PubMed	Affinity Capture-MS
BioGRID:119636	BioGRID:113885	UBL4A	BioGRID	PubMed	Affinity Capture-MS
BioGRID:119636	BioGRID:119068	WRAP73	BioGRID	PubMed	Affinity Capture-MS

Process	Evidence Code	Pubs
tail-anchored membrane protein insertion into ER membrane	IMP Inferred from Mutant Phenotype more info
transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
BAT3 complex	IDA Inferred from Direct Assay more info
cytoplasm	IEA Inferred from Electronic Annotation more info
cytosol	IDA Inferred from Direct Assay more info

General protein information

Preferred Names: Golgi to ER traffic protein 4 homolog

Names: Golgi to ER traffic protein 4 homolog; H_NH1244M04.5; conserved edge protein; conserved edge expressed protein; conserved edge-expressed protein; transmembrane domain recognition complex, 35kDa; transmembrane domain recognition complex 35 kDa subunit

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_015949.2 → NP_057033.2 Golgi to ER traffic protein 4 homolog

Status: VALIDATED

Source sequence(s)

AL133014, BG109419, BM843540, BM980767

Consensus CDS

CCDS5317.1

UniProtKB/Swiss-Prot

Q7L5D6

Related

ENSP00000265857, OTTHUMP00000140263, ENST00000265857, OTTHUMT00000231930

Conserved Domains (1) summary

pfam04190
Location:54 – 292
Blast Score: 842

DUF410; Protein of unknown function (DUF410)

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000007.13 Reference GRCh37.p5 Primary Assembly

Range

916191..936071

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000139.1 Alternate HuRef

Range

834798..854061

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CRA_TCAGchr7v2

Genomic

AC_000068.1 Alternate CRA_TCAGchr7v2

Range

971141..990596

Download

GenBank, FASTA, Sequence Viewer (Graphics)

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AC073957.7	None
genomic	AC099731.5 (211863..214249)	None
genomic	CH236965.1	EAL23708.1
genomic	CH471144.1	EAW87179.1
		EAW87180.1
mRNA	AF132954.1	AAD27729.1
mRNA	AK023560.1	None
mRNA	AK024305.1	BAG51289.1
mRNA	AK097899.1	BAG53546.1
mRNA	AK125863.1	BAG54258.1
mRNA	AL133014.1	CAB61355.1
mRNA	BC003550.1	AAH03550.2
mRNA	BG109419.1	None
mRNA	BM843540.1	None
mRNA	BM980767.1	None