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JKAMP JNK1/MAPK8-associated membrane protein [ Homo sapiens (human) ]

Gene ID: 51528, updated on 8-May-2016
Official Symbol
JKAMPprovided by HGNC
Official Full Name
JNK1/MAPK8-associated membrane proteinprovided by HGNC
Primary source
HGNC:HGNC:20184
See related
Ensembl:ENSG00000050130 HPRD:12623; MIM:611176
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
JAMP; CDA06; HSPC213; HSPC327; C14orf100
Orthologs
Location:
14q23.1
Exon count:
8
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 14 NC_000014.9 (59484443..59505407)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (59951161..59972081)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 135 Neighboring gene trans-L-3-hydroxyproline dehydratase Neighboring gene coiled-coil domain containing 175 Neighboring gene reticulon 1 Neighboring gene microRNA 5586 Neighboring gene uncharacterized LOC105370524 Neighboring gene leucine rich repeat containing 9

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ46787

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ubiquitin protein ligase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
ER-associated ubiquitin-dependent protein catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
response to unfolded protein IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
JNK1/MAPK8-associated membrane protein
Names
JNK-associated membrane protein
Jun N-terminal kinase 1-associated membrane protein
medulloblastoma antigen MU-MB-50.4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098625.2NP_001092095.1  JNK1/MAPK8-associated membrane protein isoform 2

    See identical proteins and their annotated locations for NP_001092095.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AL121694, BC005198, BX161501, DC381037, HY340214
    Consensus CDS
    CCDS45117.1
    UniProtKB/Swiss-Prot
    Q9P055
    Related
    ENSP00000389699, OTTHUMP00000244974, ENST00000425728, OTTHUMT00000411433
    Conserved Domains (1) summary
    pfam05571
    Location:3295
    DUF766; Protein of unknown function (DUF766)
  2. NM_001284201.1NP_001271130.1  JNK1/MAPK8-associated membrane protein isoform 3

    See identical proteins and their annotated locations for NP_001271130.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice site in the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) is longer and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AK056145, AL121694, BX161501, DC381037, HY340214
    Consensus CDS
    CCDS61462.1
    UniProtKB/Swiss-Prot
    Q9P055
    UniProtKB/TrEMBL
    B3KPC2, G3V2M4
    Related
    ENSP00000450749, OTTHUMP00000244977, ENST00000554271, OTTHUMT00000411437
    Conserved Domains (1) summary
    pfam05571
    Location:23315
    DUF766; Protein of unknown function (DUF766)
  3. NM_001284202.1NP_001271131.1  JNK1/MAPK8-associated membrane protein isoform 4

    See identical proteins and their annotated locations for NP_001271131.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) contains an alternate exon and uses an alternate in-frame splice in the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (4) is longer and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AL121694, BX161501, DC381037, HY340214
    Consensus CDS
    CCDS61463.1
    UniProtKB/Swiss-Prot
    Q9P055
    Related
    ENSP00000348351, ENST00000356057
    Conserved Domains (1) summary
    pfam05571
    Location:17309
    DUF766; Protein of unknown function (DUF766)
  4. NM_001284203.1NP_001271132.1  JNK1/MAPK8-associated membrane protein isoform 5

    See identical proteins and their annotated locations for NP_001271132.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) uses an alternate splice site in the 5' region and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (5) has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AK298209, AL121694, BX161501, DC381037, HY340214
    UniProtKB/Swiss-Prot
    Q9P055
    UniProtKB/TrEMBL
    A0A024R666
    Conserved Domains (1) summary
    pfam05571
    Location:1238
    DUF766; Protein of unknown function (DUF766)
  5. NM_001284204.1NP_001271133.1  JNK1/MAPK8-associated membrane protein isoform 6

    See identical proteins and their annotated locations for NP_001271133.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (6) has a shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    AF212245, AL121694, BU928810, BX161501, DC381037, HY340214
    UniProtKB/Swiss-Prot
    Q9P055
    UniProtKB/TrEMBL
    A0A087WVY6
    Related
    ENSP00000479775, ENST00000616435
    Conserved Domains (1) summary
    pfam05571
    Location:9213
    DUF766; Protein of unknown function (DUF766)
  6. NM_016475.4NP_057559.2  JNK1/MAPK8-associated membrane protein isoform 1

    See identical proteins and their annotated locations for NP_057559.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AL121694, AL136696, BX161501, DC381037, HY340214
    Consensus CDS
    CCDS45116.1
    UniProtKB/Swiss-Prot
    Q9P055
    Related
    ENSP00000261247, OTTHUMP00000244973, ENST00000261247, OTTHUMT00000411430
    Conserved Domains (1) summary
    pfam05571
    Location:9301
    DUF766; Protein of unknown function (DUF766)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p2 Primary Assembly

    Range
    59484443..59505407
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006720171.2XP_006720234.1  

    Related
    ENSP00000450813, OTTHUMP00000244978, ENST00000554795, OTTHUMT00000411438
    Conserved Domains (1) summary
    pfam05571
    Location:23227
    DUF766; Protein of unknown function (DUF766)

Alternate CHM1_1.1

Genomic

  1. NC_018925.2 Alternate CHM1_1.1

    Range
    59889332..59910305
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)