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    AIG1 androgen-induced 1 [ Homo sapiens (human) ]

    Gene ID: 51390, updated on 5-May-2013
    Official Symbol
    AIG1provided by HGNC
    Official Full Name
    androgen-induced 1provided by HGNC
    Primary source
    HGNC:21607
    Locus tag
    RP1-95L4.1
    See related
    Ensembl:ENSG00000146416; HPRD:16346; MIM:608514; Vega:OTTHUMG00000015721
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    AIG-1; dJ95L4.1; RP1-95L4.1
    Location :
    6q24.2
    Sequence :
    Chromosome: 6; NC_000006.11 (143382023..143661441)
    See AIG1 in Epigenomics, MapViewer

    Chromosome 6 - NC_000006.11Genomic Context describing neighboring genes Neighboring gene human immunodeficiency virus type I enhancer binding protein 2 Neighboring gene uncharacterized LOC100507489 Neighboring gene presenilins-associated rhomboid-like protein, mitochondrial-like Neighboring gene ribosomal protein L31 pseudogene 27 Neighboring gene chromosome 4 open reading frame 46 pseudogene

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Toward an understanding of the protein interaction network of the human liver. Wang J, et al. Mol Syst Biol, 2011 Oct 11. PMID 21988832.
    2. AIG1 is a novel Pirh2-interacting protein that activates the NFAT signaling pathway. Wu G, et al. Front Biosci (Elite Ed), 2011 Jun 1. PMID 21622095.
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.

    See all (10) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. identified a novel Pirh2-interacting protein, AIG1, by yeast two-hybrid screening and confirmed its interaction with p53 both in vitro and in vivo
      Title: AIG1 is a novel Pirh2-interacting protein that activates the NFAT signaling pathway.
    2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Submit: New GeneRIF Correction

    Review eQTL and phenotype association data in this region using PheGenI

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:119519 BioGRID:117406 RCHY1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex; Two-hybrid 

    Markers

    Genotypes

    Homology

    Clone Names

    • FLJ10485, DKFZp686F03136

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		  
    Component Evidence Code Pubs
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    Preferred Names
    androgen-induced gene 1 protein
    Names
    androgen-induced gene 1 protein

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016108.2 → NP_057192.2  androgen-induced gene 1 protein

      Status: VALIDATED

      Source sequence(s)
      BC025278, BF725860
      Consensus CDS
      CCDS5198.1
      UniProtKB/Swiss-Prot
      Q9NVV5
      Related
      ENSP00000350509, OTTHUMP00000017323, ENST00000357847, OTTHUMT00000042506
      Conserved Domains (1) summary
      pfam04750
      Location:12 – 219
      Blast Score: 560
      Far-17a_AIG1; FAR-17a/AIG1-like protein

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 104

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p10 Primary Assembly

    Genomic

    1. NC_000006.11 Reference GRCh37.p10 Primary Assembly

      Range
      143382023..143661441
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000138.1 Alternate HuRef

      Range
      140946083..141225487
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.0

    Genomic

    1. NC_018917.1 Alternate CHM1_1.0

      Range
      143380546..143659978
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    genomic ABBA01025751.1 (11787..291191) None
    genomic AL023581.1 (60160..137947) None
    genomic AL136116.11 (101..73413) None
    genomic AL391726.8 (101..121029) None
    genomic AL450335.3 (101..7489) None
    genomic AMYH01016721.1 (51..279483) None
    genomic CH471051.2 EAW47869.1
      EAW47870.1
    mRNA AF151861.1 AAD34098.1
    mRNA AF153605.1 AAD41087.1
    mRNA AJ420480.1 None
    mRNA AK001347.1 BAA91640.1
    mRNA AK222475.1 BAD96195.1
    mRNA AK298533.1 BAG60734.1
    mRNA BC009559.2 None
    mRNA BC025278.1 AAH25278.1
    mRNA BF725860.1 None
    mRNA BX538067.1 CAD97997.1
    mRNA BX640703.1 CAE45823.1
    other-genetic DQ893291.2 ABM84217.1
    other-genetic DQ896622.2 ABM87621.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9NVV5.2 GenPept UniProtKB/Swiss-Prot:Q9NVV5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Medical
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • Order cDNA clone
        Order cDNA clone
      • BioAssay
        Related PubChem BioAssays
      • BioProjects
        BioProjects related to a gene
      • CCDS
        Links from Gene to CCDS are established if a gene encodes a protein sequence that is a member of a Consensus CDS (CCDS).
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • dbVar
        Link from Gene to dbVar
      • EST
        Link to related EST entry
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • GAP
        GAP Links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • OMIM
        Links between OMIM and Gene are calculated by Gene based on MIM numbers included in the summary and phenotype sections of the Gene record.
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed (OMIM)
        Links are provided when Gene has a link to a record in OMIM, and OMIM explicitly cites these publications in PubMed.
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • SNP: Genotype
        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

      Links to other resources

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