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LACTB2 lactamase beta 2 [ Homo sapiens (human) ]

Gene ID: 51110, updated on 8-Aug-2016
Official Symbol
LACTB2provided by HGNC
Official Full Name
lactamase beta 2provided by HGNC
Primary source
HGNC:HGNC:18512
See related
Ensembl:ENSG00000147592 HPRD:13955; Vega:OTTHUMG00000164430
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CGI-83
Orthologs
Location:
8q13.3
Exon count:
7
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 8 NC_000008.11 (70637266..70669212, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (71549501..71581447, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375890 Neighboring gene LACTB2 antisense RNA 1 Neighboring gene translocation associated membrane protein 1 Neighboring gene RNA, 7SL, cytoplasmic 19, pseudogene Neighboring gene XK related 9 Neighboring gene uncharacterized LOC105375894 Neighboring gene EYA transcriptional coactivator and phosphatase 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
endoribonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
single-stranded RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
zinc ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
RNA phosphodiester bond hydrolysis, endonucleolytic IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
beta-lactamase-like protein 2
Names
lactamase, beta 2
testicular secretory protein Li 23

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016027.2NP_057111.1  beta-lactamase-like protein 2

    See identical proteins and their annotated locations for NP_057111.1

    Status: VALIDATED

    Source sequence(s)
    AC022731, AF151841, DB445101
    Consensus CDS
    CCDS6208.1
    UniProtKB/Swiss-Prot
    Q53H82
    UniProtKB/TrEMBL
    A0A024R811
    Related
    ENSP00000276590, OTTHUMP00000226692, ENST00000276590, OTTHUMT00000378748
    Conserved Domains (2) summary
    smart00849
    Location:32199
    Lactamase_B; Metallo-beta-lactamase superfamily
    COG0491
    Location:23217
    GloB; Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II [General function prediction only]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p7 Primary Assembly

    Range
    70637266..70669212 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018919.2 Alternate CHM1_1.1

    Range
    71605012..71636965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)