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Exosc9 exosome component 9 [ Mus musculus (house mouse) ]

Gene ID: 50911, updated on 8-May-2016
Official Symbol
Exosc9provided by MGI
Official Full Name
exosome component 9provided by MGI
Primary source
MGI:MGI:1355319
See related
Ensembl:ENSMUSG00000027714 Vega:OTTMUSG00000002113
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
p5; p6; RRP45; Pmscl1; PM/Scl-75
Orthologs
Location:
3; 3 B
Exon count:
12
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 3 NC_000069.6 (36552606..36565727)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (36451528..36464649)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene 11549 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene cyclin A2 Neighboring gene Bardet-Biedl syndrome 7 (human) Neighboring gene transient receptor potential cation channel, subfamily C, member 3 Neighboring gene predicted gene, 35856

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
AU-rich element binding IBA
Inferred from Biological aspect of Ancestor
more info
 
AU-rich element binding ISO
Inferred from Sequence Orthology
more info
 
RNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II activating transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
exonuclease activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
nuclease activity IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
RNA processing IEA
Inferred from Electronic Annotation
more info
 
U1 snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
 
U4 snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
 
U5 snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
 
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay IBA
Inferred from Biological aspect of Ancestor
more info
 
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay ISO
Inferred from Sequence Orthology
more info
 
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
 
nuclear mRNA surveillance IBA
Inferred from Biological aspect of Ancestor
more info
 
nuclear mRNA surveillance ISO
Inferred from Sequence Orthology
more info
 
nuclear polyadenylation-dependent mRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
nuclear polyadenylation-dependent rRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
nuclear polyadenylation-dependent rRNA catabolic process ISO
Inferred from Sequence Orthology
more info
 
nuclear polyadenylation-dependent tRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
nuclear-transcribed mRNA catabolic process ISO
Inferred from Sequence Orthology
more info
 
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of cell growth ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
rRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
 
exosome (RNase complex) ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
nuclear chromosome ISO
Inferred from Sequence Orthology
more info
 
nuclear exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
 
nuclear exosome (RNase complex) ISO
Inferred from Sequence Orthology
more info
 
nucleolus TAS
Traceable Author Statement
more info
PubMed 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
exosome complex component RRP45
Names
P75 polymyositis-scleroderma overlap syndrome-associated autoantigen
autoantigen PM/Scl 1
exosome complex exonuclease RRP45
polymyositis/scleroderma autoantigen 1
polymyositis/scleroderma autoantigen 75 kDa
NP_062266.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019393.2NP_062266.1  exosome complex component RRP45

    See identical proteins and their annotated locations for NP_062266.1

    Status: VALIDATED

    Source sequence(s)
    AK011636, BE634487, BY078098
    Consensus CDS
    CCDS17312.1
    UniProtKB/Swiss-Prot
    Q9JHI7
    Related
    ENSMUSP00000029269, OTTMUSP00000002019, ENSMUST00000029269, OTTMUST00000004267
    Conserved Domains (2) summary
    cd11368
    Location:6264
    RNase_PH_RRP45; RRP45 subunit of eukaryotic exosome
    COG2123
    Location:10271
    Rrp42; Exosome complex RNA-binding protein Rrp42, RNase PH superfamily [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p3 C57BL/6J

    Range
    36552606..36565727
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000025.1 Alternate Mm_Celera

    Range
    36436372..36449916
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)