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HP1BP3 heterochromatin protein 1 binding protein 3 [ Homo sapiens (human) ]

Gene ID: 50809, updated on 26-May-2016
Official Symbol
HP1BP3provided by HGNC
Official Full Name
heterochromatin protein 1 binding protein 3provided by HGNC
Primary source
HGNC:HGNC:24973
See related
Ensembl:ENSG00000127483 HPRD:11026; MIM:616072; Vega:OTTHUMG00000002622
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HP1BP74; HP1-BP74
Orthologs
Location:
1p36.12
Exon count:
15
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 1 NC_000001.11 (20742677..20787310, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (21069170..21113808, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene kinesin family member 17 Neighboring gene SH2 domain containing 5 Neighboring gene eukaryotic translation initiation factor 4 gamma 3 Neighboring gene uncharacterized LOC105376830 Neighboring gene uncharacterized LOC105376829 Neighboring gene microRNA 1256

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC43701

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
nucleosome binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cellular response to hypoxia IDA
Inferred from Direct Assay
more info
PubMed 
heterochromatin organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleosome assembly IEA
Inferred from Electronic Annotation
more info
 
regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of nucleus size IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
chromosome IDA
Inferred from Direct Assay
more info
PubMed 
nucleosome IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
heterochromatin protein 1-binding protein 3
Names
HP1-BP74
heterochromatin protein 1, binding protein 3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016287.3NP_057371.2  heterochromatin protein 1-binding protein 3

    See identical proteins and their annotated locations for NP_057371.2

    Status: VALIDATED

    Source sequence(s)
    AK023129, AK025754
    Consensus CDS
    CCDS30621.1
    UniProtKB/Swiss-Prot
    Q5SSJ5
    Related
    ENSP00000312625, OTTHUMP00000002716, ENST00000312239, OTTHUMT00000007457
    Conserved Domains (2) summary
    smart00526
    Location:253319
    H15; Domain in histone families 1 and 5
    cd00073
    Location:155245
    H15; linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p2 Primary Assembly

    Range
    20742677..20787310 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005245875.3XP_005245932.1  

    See identical proteins and their annotated locations for XP_005245932.1

    UniProtKB/Swiss-Prot
    Q5SSJ5
    Conserved Domains (2) summary
    smart00526
    Location:253319
    H15; Domain in histone families 1 and 5
    cd00073
    Location:155245
    H15; linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated ...
  2. XM_005245879.3XP_005245936.1  

    See identical proteins and their annotated locations for XP_005245936.1

    UniProtKB/Swiss-Prot
    Q5SSJ5
    Conserved Domains (2) summary
    smart00526
    Location:215281
    H15; Domain in histone families 1 and 5
    cd00073
    Location:117207
    H15; linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated ...
  3. XM_011541533.1XP_011539835.1  

    See identical proteins and their annotated locations for XP_011539835.1

    UniProtKB/Swiss-Prot
    Q5SSJ5
    Conserved Domains (2) summary
    smart00526
    Location:215281
    H15; Domain in histone families 1 and 5
    cd00073
    Location:117207
    H15; linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated ...
  4. XM_011541534.1XP_011539836.1  

    See identical proteins and their annotated locations for XP_011539836.1

    UniProtKB/Swiss-Prot
    Q5SSJ5
    Conserved Domains (2) summary
    smart00526
    Location:215281
    H15; Domain in histone families 1 and 5
    cd00073
    Location:117207
    H15; linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated ...
  5. XM_005245877.3XP_005245934.1  

    See identical proteins and their annotated locations for XP_005245934.1

    UniProtKB/Swiss-Prot
    Q5SSJ5
    Conserved Domains (2) summary
    smart00526
    Location:253319
    H15; Domain in histone families 1 and 5
    cd00073
    Location:155245
    H15; linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated ...
  6. XM_005245876.3XP_005245933.1  

    See identical proteins and their annotated locations for XP_005245933.1

    UniProtKB/Swiss-Prot
    Q5SSJ5
    Conserved Domains (2) summary
    smart00526
    Location:253319
    H15; Domain in histone families 1 and 5
    cd00073
    Location:155245
    H15; linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated ...
  7. XM_011541532.1XP_011539834.1  

    See identical proteins and their annotated locations for XP_011539834.1

    UniProtKB/Swiss-Prot
    Q5SSJ5
    Conserved Domains (2) summary
    smart00526
    Location:215281
    H15; Domain in histone families 1 and 5
    cd00073
    Location:117207
    H15; linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated ...
  8. XM_005245878.3XP_005245935.1  

    See identical proteins and their annotated locations for XP_005245935.1

    UniProtKB/Swiss-Prot
    Q5SSJ5
    Conserved Domains (2) summary
    smart00526
    Location:253319
    H15; Domain in histone families 1 and 5
    cd00073
    Location:155245
    H15; linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated ...
  9. XM_011541535.1XP_011539837.1  

    Related
    ENSP00000403039, OTTHUMP00000002720, ENST00000438032, OTTHUMT00000007461
    Conserved Domains (2) summary
    smart00526
    Location:253319
    H15; Domain in histone families 1 and 5
    cd00073
    Location:155245
    H15; linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated ...

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 Alternate CHM1_1.1

    Range
    21179997..21223982 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)