IL22 interleukin 22 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: IL22provided by VGNC
Official Full Name: interleukin 22provided by VGNC
Primary source: VGNC:VGNC:30143
See related: BGD:BT11527; Ensembl:ENSBTAG00000015407
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: IL-22
Orthologs: human all
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Genomic context

Location:: chromosome: 5

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	5	NC_037332.1 (45504700..45529266)

Chromosome 5 - NC_037332.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results support previous gene transcription studies and extend the observation of increased IL-22 and IL-17A responses in M. bovis-infected animals to the level of protein production.
Title: CD4+ and γδ T Cells are the main Producers of IL-22 and IL-17A in Lymphocytes from Mycobacterium bovis-infected Cattle.
SNPs in IFNG, IFNGR1 and R2, IL22, and IL22RA1 were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.
Title: Identification of SNPs in interferon gamma, interleukin-22, and their receptors and associations with health and production-related traits in Canadian Holstein bulls.
Study concludes that bovine gamma/delta T cells are important sources of IL-22 and suggest a role for this cytokine in regulating immune responses at mucosal surfaces, including the gut.
Title: Expression and regulation of IL-22 by bovine peripheral blood gamma/delta T cells.

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General gene information

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Markers

MARC_33707-33708:1054126533:1 (e-PCR)
- UniSTS:466758

MARC_33713-33714:1054127515:1 (e-PCR)
- UniSTS:466761

MARC_33723-33724:1061233036:1 (e-PCR)
- UniSTS:466766

MARC_33727-33728:1054064977:1 (e-PCR)
- UniSTS:466768

MARC_33733-33734:1054131916:1 (e-PCR)
- UniSTS:466771

MARC_33737-33738:1054134274:1 (e-PCR)
- UniSTS:466773

MARC_33743-33744:1055170573:1 (e-PCR)
- UniSTS:466775

Gene Ontology Provided by RefSeq

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: interleukin-22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.