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LINJ_35_1730 putative cysteine peptidase, Clan CA, family C19 [ Leishmania infantum JPCM5 ]

Gene ID: 5073080, updated on 28-Dec-2023

Summary

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Gene symbol
LINJ_35_1730
Gene description
putative cysteine peptidase, Clan CA, family C19
Locus tag
LINJ_35_1730
Gene type
protein coding
RNA name
putative cysteine peptidase, Clan CA, family C19
RefSeq status
PROVISIONAL
Organism
Leishmania infantum JPCM5 (strain: JPCM5)
Lineage
Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania
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Genomic context

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Location:
chromosome: 35
Exon count:
1
Sequence:
Chromosome: 35; NC_009419.2 (711812..715306, complement)

Chromosome 35 - NC_009419.2Genomic Context describing neighboring genes Neighboring gene putative cyclophilin 14 Neighboring gene putative casein kinase II Neighboring gene dynein-associated roadblock protein-like protein Neighboring gene conserved hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009419.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative genomic analysis of three Leishmania species that cause diverse human disease. Peacock CS, et al. Nat Genet, 2007 Jul. PMID 17572675, Free PMC Article
  2. Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Rogers MB, et al. Genome Res, 2011 Dec. PMID 22038252, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of protein stability IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Names
putative cysteine peptidase, Clan CA, family C19
putative ubiquitin hydrolase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_009419.2 Reference assembly

    Range
    711812..715306 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001468956.1 → XP_001468993.1  putative cysteine peptidase, Clan CA, family C19 [Leishmania infantum JPCM5]

    See identical proteins and their annotated locations for XP_001468993.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2K4Z666, A0A381MUM2, A0A6L0Y096, A4IB74
    Conserved Domains (2) summary
    cl02553
    Location:144 → 474
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam12436
    Location:761 → 857
    USP7_ICP0_bdg; ICP0-binding domain of Ubiquitin-specific protease 7
Nucleotide Protein
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