PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 [ Homo sapiens ]

Gene ID: 5058, updated on 19-May-2012

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Summary

Official Symbol: PAK1provided by HGNC
Official Full Name: p21 protein (Cdc42/Rac)-activated kinase 1provided by HGNC
Primary source: HGNC:8590
See related: Ensembl:ENSG00000149269; HPRD:03995; MIM:602590; Vega:OTTHUMG00000165138
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: PAKalpha; MGC130000; MGC130001
Summary: This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

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Genomic context

Location :: 11q13-q14

Sequence :: Chromosome: 11; NC_000011.9 (77033060..77185108, complement)

See PAK1 in Epigenomics, MapViewer

Chromosome 11 - NC_000011.9 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these results provide evidence that PAK1 specifically phosphorylates beta-catenin at S663 and that this phosphorylation is essential for the PAK1-mediated transcriptional activation of beta-catenin.
Title: Phosphorylation of β-catenin at serine 663 regulates its transcriptional activity.
Findings demonstrate that Pak1 phosphorylates BAD directly at S111, but phosphorylated S112 through Raf-1.
Title: p21-Activated kinase 1 (Pak1) phosphorylates BAD directly at serine 111 in vitro and indirectly through Raf-1 at serine 112.
crystal structures of the phosphorylated and unphosphorylated PAK1 kinase domain.
Title: Structural insights into the autoactivation mechanism of p21-activated protein kinase.
a Rac1/PAK1 cascade controls beta-catenin S675 phosphorylation and full activation in colon cancer cells
Title: A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells.
Smad4 suppresses the PAK1, which promotes the PUMA destabilization
Title: Novel tumor suppressive function of Smad4 in serum starvation-induced cell death through PAK1-PUMA pathway.
In colorectal neoplasms p-21 activated kinase 1 knockdown inhibits beta-catenin signalling and blocks cell proliferation and migration.
Title: P-21 activated kinase 1 knockdown inhibits β-catenin signalling and blocks colorectal cancer growth.
results suggest that CIB1 positively regulates cell migration and is necessary for the recruitment of FAK to the focal adhesions. Furthermore, CIB1-induced cell migration is dependent on MAP kinase signaling and its function is attenuated by PAK1
Title: Contra-regulation of calcium- and integrin-binding protein 1-induced cell migration on fibronectin by PAK1 and MAP kinase signaling.
increased activation of associated PAK1 can contribute to enhanced Cx43 dephosphorylation and impaired intercellular coupling that may underlie slow conduction in heart failure
Title: Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43.
A Rac-PAK1-Ajuba feedback loop integrates spatiotemporal signaling with actin remodeling at cell-cell contacts and stabilizes preassembled cadherin complexes.
Title: Ajuba is required for Rac activation and maintenance of E-cadherin adhesion.
Inhibition or ablation of p21-activated kinase (PAK1) disrupts glucose homeostatic mechanisms in vivo.
Title: Inhibition or ablation of p21-activated kinase (PAK1) disrupts glucose homeostatic mechanisms in vivo.

Submit: New GeneRIF Correction See all (121)

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Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

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HIV-1 protein interactions

Protein	Gene	Interaction	Pubs
Nef	nef	HIV-1 Nef binding and activation of the PAK-related kinase and phosphorylation of its substrate (a complex composed of PIX and p95) are readily detected in both infected primary T lymphocytes and macrophages	PubMed
	nef	HIV-1 Nef-mediated p21-activated kinase (PAK) activation involves the binding of Nef and phosphatidylinositol 3-kinase (PI3K)	PubMed
	nef	The activation of Nef-associated kinase (NAK; also known as p21-activated kinase 1 or PAK1) by HIV-1 Nef is via the small GTPases Cdc42 and Rac1, suggesting an interaction between Nef and these GTPases	PubMed
	nef	HIV-1 Nef-mediated activation of a PAK-related kinase correlates with the induction of high virus loads and the development of AIDS in infected rhesus macaques	PubMed
	nef	The association of HIV-1 Nef with the cellular serine kinase PAK enhances efficient proviral DNA synthesis and virion infectivity	PubMed
	nef	A cellular serine kinase is found to specifically associate with HIV-1 Nef; proteins of 62 kDa and 72 kDa, which coimmunoprecipitated with Nef, are phosphorylated in in vitro kinase assays	PubMed
Tat	tat	HIV-1 Tat induces actin cytoskeletal rearrangements through p21-activated kinase 1 (PAK1) and downstream activation of the endothelial NADPH oxidase, an effect that is lost by introduction of mutations into the Tat cysteine-rich or basic domains	PubMed

Go to the HIV-1, Human Protein Interaction Database

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Products	Interactant	Other Gene	Source	Pubs	Description
AAC24716.1		RAC1	BIND	PubMed	Active GTP-bound RAC1 interacts with PAK1B. This interaction was modelled on a demonstrated interaction between chicken RAC1 and human PAK1B.
NP_002567.3	NP_004300.1	ARHGDIA	BIND	PubMed	Pak1 interacts with and phosphorylates RhoGDI. This interaction was modeled on a demonstrated interaction between Pak1 from an unspecified species and human RhoGDI.
NP_002567.3		CDC42	BIND	PubMed	Cdc42 interacts with Pak1. This interaction was modelled on a demonstrated interaction between Cdc42 from an unspecified species and human Pak1.
NP_002567.3		CDC42	BIND	PubMed	PAK1 interacts with an unspecified isoform of Cdc42. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Cdc42.
NP_002567.3	NP_005219.2	EGFR	BIND	PubMed	Tyrosine-phosphorylated EGFR interacts with PAK1.
NP_002567.3	NP_002077.1	GRB2	BIND	PubMed	PAK1 interacts with Grb2.
NP_002567.3	NP_778224.1	HIST4H4	BIND	PubMed	PAK1 phosphorylates H4. This interaction was modeled on a demonstrated interaction between human PAK1 and H4 from an unspecified species.
NP_002567.3	NP_000256.1	NCF1C	BIND	PubMed	Pak1 interacts with and phosphorylates P47. This interaction was modeled on a demonstrated interaction between Pak1 and P47 from unspecified species.
NP_002567.3	NP_006144.1	NCK1	BIND	PubMed	Nck interacts with PAK1
NP_002567.3	NP_000259.1	NF2	BIND	PubMed	Merlin interacts with Pak1
NP_002567.3		RAC1	BIND	PubMed	PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between human PAK1 and Rac from Chinese hamster.
NP_002567.3		RAC1	BIND	PubMed	Rac1 interacts with Pak1. This interaction was modelled on a demonstrated interacton between Rac1 from an unspecified species and human Pak1.
NP_002567.3		RAC1	BIND	PubMed	PAK1 interacts with an unspecified isoform of Rac. This interaction was modeled on a demonstrated interaction between PAK1 from an unspecified species and human Rac.
NP_002567.3		RAC1	BIND	PubMed	Rac1 interacts with Pak1. This interaction was modeled on a demonstrated interaction between Rac1 and Pak1 from an unspecified species.
NP_002567.3	NP_067028.1	RHOU	BIND	PubMed	Wrch-1 interacts with PAK. This interaction was modeled on a demonstrated interactions between human Wrch-1 and rat PAK.
NP_002567.3	NP_055816.2	SPEN	BIND	PubMed	Pak1 phosphorylates SHARP. This interaction was modeled on a demonstrated interaction between Pak1 and SHARP both from an unspecified species.
NP_002567.3	NP_003233.3	TGFBR2	BIND	PubMed	T-beta-RII interacts with PAK1. This interaction was modeled on a demonstrated interaction between human T-beta-RII and mouse PAK1.
NP_002567.3			BIND	PubMed	PAK1 interacts with GTP-RAC1. This interaction was modeled on a demonstrated interaction between PAK1 and GTP-RAC from unspecified species.
NP_002567.3			BIND	PubMed	PAK1 interacts with GTP-RAC1.
NP_002567.3			BIND	PubMed	PAK1 interacts with GTP-RAC1 (GTP-RAC).
NP_002567.3			BIND	PubMed	PAK interacts with GTP-bound Rac.
NP_002567.3			BIND	PubMed	GTP-bound TCL interacts with PAK-1.
Q13153	Q9P2A4	ABI3	HPRD	PubMed
Q13153	P68133	ACTA1	HPRD	PubMed
Q13153	Q04771	ACVR1	HPRD	PubMed
Q13153	P31749	AKT1	HPRD	PubMed
Q13153	Q92974	ARHGEF2	HPRD	PubMed
Q13153	Q15052	ARHGEF6	HPRD	PubMed
Q13153	Q14155	ARHGEF7	HPRD	PubMed
Q13153	O15143	ARPC1B	HPRD	PubMed
Q13153	Q92934	BAD	HPRD	PubMed
Q13153	O00238	BMPR1B	HPRD	PubMed
Q13153	P51813	BMX	HPRD	PubMed
Q13153	P29466	CASP1	HPRD	PubMed
Q13153	P60953	CDC42	HPRD	PubMed
Q13153	Q9UQ88	CDK11A	HPRD	PubMed
Q13153	P21127	CDK11B	HPRD	PubMed
Q13153	Q00535	CDK5	HPRD	PubMed
Q13153	Q15078	CDK5R1	HPRD	PubMed
Q13153	P02452	COL1A1	HPRD	PubMed
Q13153	Cysteine-rich PAK1 inhibitor	CRIPAK	HPRD	PubMed
Q13153	P68400	CSNK2A1	HPRD	PubMed
Q13153	P19784	CSNK2A2	HPRD	PubMed
Q13153	O60469	DSCAM	HPRD	PubMed
Q13153	P63167	DYNLL1	HPRD	PubMed
Q13153	P00533	EGFR	HPRD	PubMed
Q13153	P04626	ERBB2	HPRD	PubMed
Q13153	P03372	ESR1	HPRD	PubMed
Q13153	P21333	FLNA	HPRD	PubMed
Q13153	P58012	FOXL2	HPRD	PubMed
Q13153	Q12778	FOXO1	HPRD	PubMed
Q13153	Q8WU20	FRS2	HPRD	PubMed
Q13153	Q14161	GIT2	HPRD	PubMed
Q13153	P62993	GRB2	HPRD	PubMed
Q13153	O14964	HGS	HPRD	PubMed
Q13153	H4 Histone family, member A	HIST1H4A	HPRD	PubMed
Q13153	P53667	LIMK1	HPRD	PubMed
Q13153	Q02750	MAP2K1	HPRD	PubMed
Q13153	P28482	MAPK1	HPRD	PubMed
Q13153	P02686	MBP	HPRD	PubMed
Q13153	Q15746	MYLK	HPRD	PubMed
Q13153	P14598	NCF1	HPRD	PubMed
Q13153	P16333	NCK1	HPRD	PubMed
Q13153	O43639	NCK2	HPRD	PubMed
Q13153	P35240	NF2	HPRD	PubMed
Q13153	O95747	OXSR1	HPRD	PubMed
Q13153	Q13153	PAK1	HPRD	PubMed
Q13153	Q9NWT1	PAK1IP1	HPRD	PubMed
Q13153	O15530	PDPK1	HPRD	PubMed
Q13153	P19174	PLCG1	HPRD	PubMed
Q13153	P49593	PPM1F	HPRD	PubMed
Q13153	Q05655	PRKCD	HPRD	PubMed
Q13153	P49023	PXN	HPRD	PubMed
Q13153	P63000	RAC1	HPRD	PubMed
Q13153	P04049	RAF1	HPRD	PubMed
Q13153	Q9H4E5	RHOJ	HPRD	PubMed
Q13153	Rho GTPase like protein ARHU	RHOU	HPRD	PubMed
Q13153	P29353	SHC1	HPRD	PubMed
Q13153	Q15797	SMAD1	HPRD	PubMed
Q13153	Q15796	SMAD2	HPRD	PubMed
Q13153	Q13485	SMAD4	HPRD	PubMed
Q13153	Q9HCE7	SMURF1	HPRD	PubMed
Q13153	Arg binding protein 2	SORBS2	HPRD	PubMed
Q13153	P17600	SYN1	HPRD	PubMed
Q13153	P36897	TGFBR1	HPRD	PubMed
Q13153	P37173	TGFBR2	HPRD	PubMed
Q13153	P61981	YWHAG	HPRD	PubMed
BioGRID:111095	BioGRID:119389	ABI3	BioGRID	PubMed	Reconstituted Complex
BioGRID:111095	BioGRID:106710	AKT1	BioGRID	PubMed	Reconstituted Complex
BioGRID:111095	BioGRID:114618	ARHGEF2	BioGRID	PubMed	Affinity Capture-MS; Reconstituted Complex
BioGRID:111095	BioGRID:114847	ARHGEF6	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:114393	ARHGEF7	BioGRID	PubMed	Affinity Capture-Western; Two-hybrid
BioGRID:111095	BioGRID:115402	ARPC1B	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111095	BioGRID:115721	BAIAP2	BioGRID	PubMed	Reconstituted Complex
BioGRID:111095	BioGRID:107128	BMX	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111095	BioGRID:122413	C5orf42	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:107433	CDC42	BioGRID	PubMed	Reconstituted Complex; Two-hybrid
BioGRID:111095	BioGRID:609064	CDK11A	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
BioGRID:111095	BioGRID:107455	CDK5	BioGRID	PubMed	Affinity Capture-Western; Biochemical Activity
BioGRID:111095	BioGRID:114206	DYNLL1	BioGRID	PubMed	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
BioGRID:111095	BioGRID:114596	DYRK1B	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:108376	ERBB2	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111095	BioGRID:114593	HGS	BioGRID	PubMed	Reconstituted Complex
BioGRID:111095	BioGRID:113955	HIST1H4A	BioGRID	PubMed	Biochemical Activity
BioGRID:111095	BioGRID:109552	HSP90AA1	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:110172	LIMK1	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111095	BioGRID:110722	MYLK	BioGRID	PubMed	Biochemical Activity
BioGRID:111095	BioGRID:120982	MYNN	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:110770	NCK1	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:111095	BioGRID:114020	NCK2	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111095	BioGRID:111095	PAK1	BioGRID	PubMed	Affinity Capture-Western; Biochemical Activity; Co-crystal Structure; Co-fractionation
BioGRID:111095	BioGRID:120335	PAK1IP1	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
BioGRID:111095	BioGRID:111330	PKLR	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111095	BioGRID:111351	PLCG1	BioGRID	PubMed	Reconstituted Complex
BioGRID:111095	BioGRID:111817	RAC1	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
BioGRID:111095	BioGRID:111831	RAF1	BioGRID	PubMed	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BioGRID:111095	BioGRID:121499	RHOJ	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:119029	SH3KBP1	BioGRID	PubMed	Affinity Capture-Western
BioGRID:111095	BioGRID:112910	TGM2	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:113164	UBC	BioGRID	PubMed	Affinity Capture-MS
BioGRID:111095	BioGRID:113364	YWHAG	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:113366	YWHAZ	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:118841	ZC3H7A	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:115735	ZNF238	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:127074	ZNF418	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:120713	ZNF823	BioGRID	PubMed	Two-hybrid
BioGRID:111095	BioGRID:120886	ZNF83	BioGRID	PubMed	Two-hybrid

Function	Evidence Code	Pubs
ATP binding	IEA Inferred from Electronic Annotation more info
collagen binding	IPI Inferred from Physical Interaction more info	PubMed
nucleotide binding	IEA Inferred from Electronic Annotation more info
protein binding	IPI Inferred from Physical Interaction more info	PubMed
contributes_to protein binding	IPI Inferred from Physical Interaction more info	PubMed
protein kinase activity	IDA Inferred from Direct Assay more info	PubMed
protein serine/threonine kinase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
NOT MAPK cascade	IDA Inferred from Direct Assay more info	PubMed
T cell costimulation	TAS Traceable Author Statement more info
T cell receptor signaling pathway	TAS Traceable Author Statement more info
actin cytoskeleton reorganization	IDA Inferred from Direct Assay more info	PubMed
actin cytoskeleton reorganization	IMP Inferred from Mutant Phenotype more info	PubMed
actin cytoskeleton reorganization	NAS Non-traceable Author Statement more info
apoptotic process	IEA Inferred from Electronic Annotation more info
axon guidance	TAS Traceable Author Statement more info
branching morphogenesis of a tube	IMP Inferred from Mutant Phenotype more info
negative regulation of cell proliferation involved in contact inhibition	IMP Inferred from Mutant Phenotype more info	PubMed
neuron projection morphogenesis	ISS Inferred from Sequence or Structural Similarity more info
positive regulation of JUN kinase activity	IMP Inferred from Mutant Phenotype more info	PubMed
positive regulation of intracellular estrogen receptor signaling pathway	IDA Inferred from Direct Assay more info	PubMed
positive regulation of peptidyl-serine phosphorylation	IDA Inferred from Direct Assay more info	PubMed
positive regulation of stress fiber assembly	IMP Inferred from Mutant Phenotype more info	PubMed
protein autophosphorylation	IDA Inferred from Direct Assay more info	PubMed
protein phosphorylation	IDA Inferred from Direct Assay more info	PubMed
wound healing	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
Z disc	ISS Inferred from Sequence or Structural Similarity more info
axon	ISS Inferred from Sequence or Structural Similarity more info
cell-cell junction	IDA Inferred from Direct Assay more info	PubMed
cytoplasm	IDA Inferred from Direct Assay more info	PubMed
cytosol	TAS Traceable Author Statement more info
dendrite	ISS Inferred from Sequence or Structural Similarity more info
colocalizes_with filamentous actin	NAS Non-traceable Author Statement more info	PubMed
focal adhesion	IEA Inferred from Electronic Annotation more info
intercalated disc	ISS Inferred from Sequence or Structural Similarity more info
nuclear membrane	ISS Inferred from Sequence or Structural Similarity more info
plasma membrane	IDA Inferred from Direct Assay more info	PubMed
protein complex	IDA Inferred from Direct Assay more info	PubMed
ruffle	IDA Inferred from Direct Assay more info	PubMed

General protein information

Preferred Names: serine/threonine-protein kinase PAK 1

Names: serine/threonine-protein kinase PAK 1; p65-PAK; alpha-PAK; STE20 homolog, yeast; p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)

NP_001122092.1

EC 2.7.11.1

NP_002567.3

EC 2.7.11.1

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_029900.1 RefSeqGene

Range

5001..157049

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001128620.1 → NP_001122092.1 serine/threonine-protein kinase PAK 1 isoform 1

Status: REVIEWED

Description

Transcript Variant: This variant (1) encodes the longer isoform (1).

Source sequence(s)

AF071884, BC050377, BC109299, BI793123, DA393732

Consensus CDS

CCDS44687.1

UniProtKB/Swiss-Prot

Q13153

Related

ENSP00000278568, OTTHUMP00000228569, ENST00000278568, OTTHUMT00000382084

Conserved Domains (3) summary

cd01093
Location:73 – 118
Blast Score: 204

CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...

smart00220
Location:270 – 517
Blast Score: 771

S_TKc; Serine/Threonine protein kinases, catalytic domain

cl09925
Location:250 – 517
Blast Score: 1495

PKc_like; Protein Kinases, catalytic domain
NM_002576.4 → NP_002567.3 serine/threonine-protein kinase PAK 1 isoform 2

Status: REVIEWED

Description

Transcript Variant: This variant (2) lacks a coding exon in the 3' region, as compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.

Source sequence(s)

BC050377, BC109299, BI793123, DA393732

Consensus CDS

CCDS8250.1

UniProtKB/Swiss-Prot

Q13153

Related

ENSP00000348696, OTTHUMP00000228568, ENST00000356341, OTTHUMT00000382083

Conserved Domains (3) summary

cd01093
Location:73 – 118
Blast Score: 203

CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...

cd06647
Location:250 – 542
Blast Score: 1607

STKc_PAK_I; Catalytic domain of the Protein Serine/Threonine Kinase, Group I p21-activated kinase

smart00220
Location:270 – 521
Blast Score: 790

S_TKc; Serine/Threonine protein kinases, catalytic domain

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000011.9 Reference GRCh37.p5 Primary Assembly

Range

77033060..77185108, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000143.1 Alternate HuRef

Range

73331052..73483383, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AP000486.6 (2275..150218)	None
genomic	AP003680.2	None
genomic	CH471076.1	EAW75026.1
		EAW75027.1
		EAW75028.1
		EAW75029.1
mRNA	AF071884.1	AAC24716.1
mRNA	AK055228.1	BAG51489.1
mRNA	AK293098.1	BAF85787.1
mRNA	AK295344.1	BAH12038.1
mRNA	AK296006.1	BAH12236.1
mRNA	BC050377.1	None
mRNA	BC109298.1	None
mRNA	BC109299.1	AAI09300.1
mRNA	BE501896.1	None
mRNA	BE502192.1	None
mRNA	BI793123.1	None
mRNA	BM451179.1	None
mRNA	DA393732.1	None
mRNA	U24152.1	AAA65441.1
mRNA	U51120.1	AAC50590.1
other-genetic	EU832767.1	ACE87778.1
other-genetic	GQ129310.1	ACT64444.1