hrg hiiragi [Drosophila melanogaster] - Gene

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Summary

Official Symbol: hrgprovided by Flybase
Official Full Name: hiiragiprovided by Flybase
Primary source: FLYBASE:FBgn0015949
Locus tag: Dmel_CG9854
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG9854; Dmel\CG9854; l(2)07619; l(2)k07619; Pap; PAP

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Genomic context

Location :: 56E1-56E1

Sequence :: Chromosome: 2R; NT_033778.3 (15551422..15557326, complement)

See hrg in Epigenomics, MapViewer

Chromosome 2R - NT_033778.3 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Interactions

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:72394	BioGRID:67421	H	BioGRID	PubMed	Phenotypic Suppression
BioGRID:72394	BioGRID:57823	N	BioGRID	PubMed	Phenotypic Enhancement
BioGRID:72394	BioGRID:68163	Ser	BioGRID	PubMed	Phenotypic Enhancement
BioGRID:72394	BioGRID:58076	dx	BioGRID	PubMed	Phenotypic Enhancement
BioGRID:72394	BioGRID:67695	orb	BioGRID	PubMed	Phenotypic Enhancement
BioGRID:72394	BioGRID:59774	sec5	BioGRID	PubMed	Two-hybrid

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General gene information

Homology

Homologs of the hrg gene: The hrg gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, A.thaliana, and rice.

Pathways from BioSystems

Cleavage of Growing Transcript in the Termination Region, organism-specific biosystem (from REACTOME)
Cleavage of Growing Transcript in the Termination Region, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Gene Expression, organism-specific biosystem (from REACTOME)
Gene Expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem (from REACTOME)
Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Processing of Capped Intronless Pre-mRNA, organism-specific biosystem (from REACTOME)
Processing of Capped Intronless Pre-mRNA, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Processing of Intronless Pre-mRNAs, organism-specific biosystem (from REACTOME)
Processing of Intronless Pre-mRNAs, organism-specific biosystemcomputationally inferred pathway (not manually curated)
RNA Polymerase II Transcription, organism-specific biosystem (from REACTOME)
RNA Polymerase II Transcription, organism-specific biosystemcomputationally inferred pathway (not manually curated)
RNA Polymerase II Transcription Termination, organism-specific biosystem (from REACTOME)
RNA Polymerase II Transcription Termination, organism-specific biosystemcomputationally inferred pathway (not manually curated)
mRNA 3'-end processing, organism-specific biosystem (from REACTOME)
mRNA 3'-end processing, organism-specific biosystemcomputationally inferred pathway (not manually curated)
mRNA Splicing, organism-specific biosystem (from REACTOME)
mRNA Splicing, organism-specific biosystemcomputationally inferred pathway (not manually curated)
mRNA Splicing - Major Pathway, organism-specific biosystem (from REACTOME)
mRNA Splicing - Major Pathway, organism-specific biosystemcomputationally inferred pathway (not manually curated)
mRNA processing, organism-specific biosystem (from WikiPathways)
mRNA processing, organism-specific biosystemThis process describes the conversion of precursor messenger RNA into mature messenger RNA (mRNA). The pre-mRNA molecule undergoes three main modifications. These modifications are 5' capping, 3' pol...
mRNA surveillance pathway, organism-specific biosystem (from KEGG)
mRNA surveillance pathway, organism-specific biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...
mRNA surveillance pathway, conserved biosystem (from KEGG)
mRNA surveillance pathway, conserved biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
RNA binding	IEA Inferred from Electronic Annotation more info
polynucleotide adenylyltransferase activity	IDA Inferred from Direct Assay more info
polynucleotide adenylyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
polynucleotide adenylyltransferase activity	NAS Non-traceable Author Statement more info

Process	Evidence Code	Pubs
mRNA polyadenylation	ISS Inferred from Sequence or Structural Similarity more info	PubMed
transcription, DNA-dependent	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
nucleus	IEA Inferred from Electronic Annotation more info

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General protein information

Preferred Names: CG9854 gene product from transcript CG9854-RA

Names: CG9854-PA; CG9854-PB; CG9854-PC; hiiragi; hrg-PA; hrg-PB; hrg-PC; poly(A) polymerase

NP_001036562.1

EC 2.7.7.19

NP_536790.1

EC 2.7.7.19

NP_725919.1

EC 2.7.7.19

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NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033778.3

Range

15551422..15557326, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_080529.2 → NP_536790.1 hiiragi, isoform A [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9N6D7

Related

FBpp0085678, FBtr0086483

Conserved Domains (3) summary

cd05402
Location:68 – 222
Blast Score: 270

NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases.

pfam04926
Location:374 – 537
Blast Score: 401

PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain

pfam04928
Location:26 – 373
Blast Score: 1465

PAP_central; Poly(A) polymerase central domain
NM_166372.1 → NP_725919.1 hiiragi, isoform B [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9N6D7

Related

FBpp0085679, FBtr0086484

Conserved Domains (3) summary

cd05402
Location:68 – 222
Blast Score: 270

NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases.

pfam04926
Location:374 – 537
Blast Score: 401

PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain

pfam04928
Location:26 – 373
Blast Score: 1465

PAP_central; Poly(A) polymerase central domain
NM_001043097.1 → NP_001036562.1 hiiragi, isoform C [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9N6D7

Related

FBpp0110309, FBtr0111010

Conserved Domains (3) summary

cd05402
Location:68 – 222
Blast Score: 270

NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases.

pfam04926
Location:374 – 537
Blast Score: 401

PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain

pfam04928
Location:26 – 373
Blast Score: 1465

PAP_central; Poly(A) polymerase central domain

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
mRNA	AF231704.1	AAF36978.1
mRNA	BT001541.1	AAN71296.1
genomic	AE013599.4	AAF57528.2
mRNA	BT050444.1	ACJ13151.1
genomic	AE013599.4	ABI31107.1
mRNA	AB018431.1	BAB03279.1
genomic	AE013599.4	AAM68424.1