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USP37 ubiquitin specific peptidase 37 [ Canis lupus familiaris (dog) ]

Gene ID: 488523, updated on 5-Mar-2024

Summary

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Official Symbol
USP37provided by VGNC
Official Full Name
ubiquitin specific peptidase 37provided by VGNC
Primary source
VGNC:VGNC:48192
See related
Ensembl:ENSCAFG00845027522
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 37
Exon count:
25
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (25106515..25202430, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (25910572..26006406, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (24965635..25061740, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (25011984..25107360, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (24945445..25041545, complement)

Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 11 member 1 Neighboring gene CTD small phosphatase 1 Neighboring gene microRNA mir-26b Neighboring gene villin 1 Neighboring gene 60S ribosomal protein L34-like Neighboring gene CCR4-NOT transcription complex subunit 9 Neighboring gene uncharacterized LOC111094340 Neighboring gene phospholipase C delta 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Lindblad-Toh K, et al. Nature, 2005 Dec 8. PMID 16341006

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin carboxyl-terminal hydrolase 37
Names
Deubiquitinating enzyme 37
Ubiquitin thiolesterase 37
Ubiquitin-specific-processing protease 37
ubiquitin thioesterase 37
NP_001300791.1
XP_038303245.1
XP_038303246.1
XP_038303247.1
XP_038303248.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001313862.2 → NP_001300791.1  ubiquitin carboxyl-terminal hydrolase 37

    Status: PROVISIONAL

    Source sequence(s)
    JAAUVH010000368
    UniProtKB/Swiss-Prot
    E2RK09, F1PGV7
    UniProtKB/TrEMBL
    A0A8C0LTN9
    Related
    ENSCAFP00845038091.1, ENSCAFT00845048558.1
    Conserved Domains (3) summary
    cd02257
    Location:864 → 951
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam00443
    Location:344 → 609
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam16674
    Location:3 → 105
    UCH_N; N-terminal of ubiquitin carboxyl-terminal hydrolase 37

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051841.1 Reference ROS_Cfam_1.0

    Range
    25106515..25202430 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038447319.1 → XP_038303247.1  ubiquitin carboxyl-terminal hydrolase 37 isoform X2

    UniProtKB/TrEMBL
    A0A8C0LTN9, A0A8C0TMJ3, A0A8I3Q1G3
    Related
    ENSCAFP00845038304.1, ENSCAFT00845048820.1
    Conserved Domains (3) summary
    COG5207
    Location:344 → 928
    UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
    pfam00443
    Location:344 → 609
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam16674
    Location:3 → 105
    UCH_N; N-terminal of ubiquitin carboxyl-terminal hydrolase 37

  2. XM_038447318.1 → XP_038303246.1  ubiquitin carboxyl-terminal hydrolase 37 isoform X1

    UniProtKB/Swiss-Prot
    E2RK09, F1PGV7
    UniProtKB/TrEMBL
    A0A8C0LTN9
    Conserved Domains (3) summary
    cd02257
    Location:864 → 951
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam00443
    Location:344 → 609
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam16674
    Location:3 → 105
    UCH_N; N-terminal of ubiquitin carboxyl-terminal hydrolase 37

  3. XM_038447317.1 → XP_038303245.1  ubiquitin carboxyl-terminal hydrolase 37 isoform X1

    UniProtKB/Swiss-Prot
    E2RK09, F1PGV7
    UniProtKB/TrEMBL
    A0A8C0LTN9
    Conserved Domains (3) summary
    cd02257
    Location:864 → 951
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam00443
    Location:344 → 609
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam16674
    Location:3 → 105
    UCH_N; N-terminal of ubiquitin carboxyl-terminal hydrolase 37

  4. XM_038447320.1 → XP_038303248.1  ubiquitin carboxyl-terminal hydrolase 37 isoform X3

    UniProtKB/TrEMBL
    A0A8C0P8F3
    Conserved Domains (2) summary
    cd02257
    Location:754 → 841
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam00443
    Location:234 → 499
    UCH; Ubiquitin carboxyl-terminal hydrolase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049297.1 Alternate UMICH_Zoey_3.1

    Range
    25011984..25107360 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

    Range
    24945445..25041545 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

    Range
    24965635..25061740 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    25910572..26006406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E2RK09.1 GenPept UniProtKB/Swiss-Prot:E2RK09

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