PLA2G2D phospholipase A2, group IID [Canis lupus familiaris (dog)] - Gene

Summary

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Gene symbol: PLA2G2D
Gene description: phospholipase A2, group IID
See related: Ensembl:ENSCAFG00000015085
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis

Genomic context

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Location :: chromosome: 2

Sequence :: Chromosome: 2; NC_006584.3 (78739855..78745571)

See PLA2G2D in MapViewer

Chromosome 2 - NC_006584.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

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Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

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Pathways from BioSystems

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Arachidonic acid metabolism, organism-specific biosystem (from KEGG)
Arachidonic acid metabolism, organism-specific biosystem
Arachidonic acid metabolism
Arachidonic acid metabolism, conserved biosystem (from KEGG)
Arachidonic acid metabolism, conserved biosystem
Arachidonic acid metabolism
Ether lipid metabolism, organism-specific biosystem (from KEGG)
Ether lipid metabolism, organism-specific biosystem
Ether lipid metabolism
Ether lipid metabolism, conserved biosystem (from KEGG)
Ether lipid metabolism, conserved biosystem
Ether lipid metabolism
Fat digestion and absorption, organism-specific biosystem (from KEGG)
Fat digestion and absorption, organism-specific biosystemFat is an important energy source from food. More than 95% of dietary fat is long-chain triacylglycerols (TAG), the remaining being phospholipids (4.5%) and sterols. In the small intestine lumen, die...
Fat digestion and absorption, conserved biosystem (from KEGG)
Fat digestion and absorption, conserved biosystemFat is an important energy source from food. More than 95% of dietary fat is long-chain triacylglycerols (TAG), the remaining being phospholipids (4.5%) and sterols. In the small intestine lumen, die...
Glycerophospholipid metabolism, organism-specific biosystem (from KEGG)
Glycerophospholipid metabolism, organism-specific biosystem
Glycerophospholipid metabolism
Glycerophospholipid metabolism, conserved biosystem (from KEGG)
Glycerophospholipid metabolism, conserved biosystem
Glycerophospholipid metabolism
Linoleic acid metabolism, organism-specific biosystem (from KEGG)
Linoleic acid metabolism, organism-specific biosystem
Linoleic acid metabolism
Linoleic acid metabolism, conserved biosystem (from KEGG)
Linoleic acid metabolism, conserved biosystem
Linoleic acid metabolism
Pancreatic secretion, organism-specific biosystem (from KEGG)
Pancreatic secretion, organism-specific biosystemThe pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two parts, the acinar and duct cells. The primary functions of pancreatic acinar cells are to synthesiz...
Pancreatic secretion, conserved biosystem (from KEGG)
Pancreatic secretion, conserved biosystemThe pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two parts, the acinar and duct cells. The primary functions of pancreatic acinar cells are to synthesiz...
Vascular smooth muscle contraction, organism-specific biosystem (from KEGG)
Vascular smooth muscle contraction, organism-specific biosystemThe vascular smooth muscle cell (VSMC) is a highly specialized cell whose principal function is contraction. On contraction, VSMCs shorten, thereby decreasing the diameter of a blood vessel to regula...
Vascular smooth muscle contraction, conserved biosystem (from KEGG)
Vascular smooth muscle contraction, conserved biosystemThe vascular smooth muscle cell (VSMC) is a highly specialized cell whose principal function is contraction. On contraction, VSMCs shorten, thereby decreasing the diameter of a blood vessel to regula...
alpha-Linolenic acid metabolism, organism-specific biosystem (from KEGG)
alpha-Linolenic acid metabolism, organism-specific biosystem
alpha-Linolenic acid metabolism
alpha-Linolenic acid metabolism, conserved biosystem (from KEGG)
alpha-Linolenic acid metabolism, conserved biosystem
alpha-Linolenic acid metabolism

General gene information

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Genotypes

See PLA2G2D SNP Geneview Report

Homology

Homologs of the PLA2G2D gene: The PLA2G2D gene is conserved in human, chimpanzee, Rhesus monkey, mouse, and rat.
OrthoDB: The Hierarchical Catalog of Eukaryotic Orthologs

General protein information

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Preferred Names: group IID secretory phospholipase A2

Names: phospholipase A2, group IID

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Build 3.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

NC_006584.3

Range

78739855..78745571

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_544524.3 → XP_544524.3

Related

ENSCAFP00000022233, ENSCAFT00000023949

Conserved Domains (1) summary

cd00125
Location:21 – 138
Blast Score: 371

PLA2c; PLA2c: Phospholipase A2, a family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a ...