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FERMT1 FERM domain containing kindlin 1 [ Canis lupus familiaris (dog) ]

Gene ID: 485775, updated on 5-Mar-2024

Summary

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Official Symbol
FERMT1provided by VGNC
Official Full Name
FERM domain containing kindlin 1provided by VGNC
Primary source
VGNC:VGNC:40822
See related
Ensembl:ENSCAFG00845027072
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 24
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (16151297..16187696)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (15570788..15607260)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (16197744..16234285)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (15757632..15794124)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (15866168..15902611)

Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119865627 Neighboring gene uncharacterized LOC111092110 Neighboring gene uncharacterized LOC111092063 Neighboring gene leucine rich repeat neuronal 4 Neighboring gene cardiolipin synthase 1 Neighboring gene tRNA methyltransferase 6 non-catalytic subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fermitin family homolog 1
Names
fermitin family member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051828.1 Reference ROS_Cfam_1.0

    Range
    16151297..16187696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038433177.1 → XP_038289105.1  fermitin family homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JGZ3
    Conserved Domains (6) summary
    smart00295
    Location:250 → 322
    B41; Band 4.1 homologues
    cd01237
    Location:370 → 493
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:564 → 655
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17180
    Location:11 → 94
    FERM_F0_KIND1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-1 (KIND1)
    cd17183
    Location:95 → 275
    FERM_F1_KIND1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-1 (KIND1)
    pfam00373
    Location:453 → 570
    FERM_M; FERM central domain

  2. XM_038433176.1 → XP_038289104.1  fermitin family homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QD59, A0A8I3QCU1
    Related
    ENSCAFP00845037456.1, ENSCAFT00845047734.1
    Conserved Domains (6) summary
    smart00295
    Location:268 → 340
    B41; Band 4.1 homologues
    cd01237
    Location:388 → 511
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:582 → 673
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17180
    Location:29 → 112
    FERM_F0_KIND1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-1 (KIND1)
    cd17183
    Location:113 → 293
    FERM_F1_KIND1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-1 (KIND1)
    pfam00373
    Location:471 → 588
    FERM_M; FERM central domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049284.1 Alternate UMICH_Zoey_3.1

    Range
    15757632..15794124
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038508376.1 → XP_038364304.1  fermitin family homolog 1 isoform X2

  2. XM_038508375.1 → XP_038364303.1  fermitin family homolog 1 isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

    Range
    15866168..15902611
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038635897.1 → XP_038491825.1  fermitin family homolog 1 isoform X2

  2. XM_038635896.1 → XP_038491824.1  fermitin family homolog 1 isoform X1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

    Range
    16197744..16234285
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038571651.1 → XP_038427579.1  fermitin family homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JGZ3

  2. XM_038571649.1 → XP_038427577.1  fermitin family homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0P211, A0A8C0QD59

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    15570788..15607260
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_542898.5 → XP_542898.3  fermitin family homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JGZ3
    Conserved Domains (6) summary
    smart00295
    Location:250 → 322
    B41; Band 4.1 homologues
    cd01237
    Location:370 → 493
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:564 → 655
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17180
    Location:11 → 94
    FERM_F0_KIND1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-1 (KIND1)
    cd17183
    Location:95 → 275
    FERM_F1_KIND1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-1 (KIND1)
    pfam00373
    Location:453 → 570
    FERM_M; FERM central domain

  2. XM_005634802.2 → XP_005634859.2  fermitin family homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QD59, A0A8P0SBF8
    Conserved Domains (6) summary
    smart00295
    Location:268 → 340
    B41; Band 4.1 homologues
    cd01237
    Location:388 → 511
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:582 → 673
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17180
    Location:29 → 112
    FERM_F0_KIND1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-1 (KIND1)
    cd17183
    Location:113 → 293
    FERM_F1_KIND1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-1 (KIND1)
    pfam00373
    Location:471 → 588
    FERM_M; FERM central domain
Nucleotide Protein
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