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PARVB parvin beta [ Canis lupus familiaris (dog) ]

Gene ID: 481215, updated on 5-Mar-2024

Summary

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Official Symbol
PARVBprovided by VGNC
Official Full Name
parvin betaprovided by VGNC
Primary source
VGNC:VGNC:108211
See related
Ensembl:ENSCAFG00845012438
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See PARVB in Genome Data Viewer
Location:
chromosome: 10
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (22300594..22397773, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (21492217..21589726, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (22513879..22611416, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (22019817..22117314, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (22340152..22437648, complement)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119873613 Neighboring gene uncharacterized LOC119873614 Neighboring gene parvin gamma Neighboring gene SAMM50 sorting and assembly machinery component Neighboring gene uncharacterized LOC119873615 Neighboring gene patatin like phospholipase domain containing 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phenotype transitions induced by mechanical stimuli in airway smooth muscle are regulated by differential interactions of parvin isoforms with paxillin and Akt. Huang Y, et al. Am J Physiol Lung Cell Mol Physiol, 2020 May 1. PMID 32130030, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Phenotype transitions induced by mechanical stimuli in airway smooth muscle are regulated by differential interactions of parvin isoforms with paxillin and Akt.
    Title: Phenotype transitions induced by mechanical stimuli in airway smooth muscle are regulated by differential interactions of parvin isoforms with paxillin and Akt.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment or maintenance of cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lamellipodium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lamellipodium IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-parvin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    22300594..22397773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038679587.1 → XP_038535515.1  beta-parvin isoform X1

    UniProtKB/TrEMBL
    A0A8C0YVL6, A0A8I3NLY7
    Related
    ENSCAFP00845017404.1, ENSCAFT00845022136.1
    Conserved Domains (2) summary
    cd21336
    Location:89 → 194
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:236 → 365
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  2. XM_038679590.1 → XP_038535518.1  beta-parvin isoform X3

    UniProtKB/TrEMBL
    A0A8C0MBM7
    Conserved Domains (2) summary
    cd21336
    Location:36 → 141
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:183 → 312
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  3. XM_038679588.1 → XP_038535516.1  beta-parvin isoform X2

    UniProtKB/TrEMBL
    A0A8C0MBM7, A0A8I3NGU9
    Related
    ENSCAFP00845017435.1, ENSCAFT00845022174.1
    Conserved Domains (2) summary
    cd21336
    Location:84 → 189
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:231 → 360
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  4. XM_038679589.1 → XP_038535517.1  beta-parvin isoform X3

    UniProtKB/TrEMBL
    A0A8C0MBM7
    Conserved Domains (2) summary
    cd21336
    Location:36 → 141
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:183 → 312
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    22019817..22117314 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038488360.1 → XP_038344288.1  beta-parvin isoform X1

    Conserved Domains (2) summary
    cd21336
    Location:89 → 194
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:236 → 365
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  2. XM_038488363.1 → XP_038344291.1  beta-parvin isoform X3

    Conserved Domains (2) summary
    cd21336
    Location:36 → 141
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:183 → 312
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  3. XM_038488361.1 → XP_038344289.1  beta-parvin isoform X2

    Conserved Domains (2) summary
    cd21336
    Location:84 → 189
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:231 → 360
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  4. XM_038488362.1 → XP_038344290.1  beta-parvin isoform X3

    Conserved Domains (2) summary
    cd21336
    Location:36 → 141
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:183 → 312
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    22340152..22437648 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038614248.1 → XP_038470176.1  beta-parvin isoform X1

    Conserved Domains (2) summary
    cd21336
    Location:89 → 194
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:236 → 365
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  2. XM_038614251.1 → XP_038470179.1  beta-parvin isoform X3

    Conserved Domains (2) summary
    cd21336
    Location:36 → 141
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:183 → 312
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  3. XM_038614249.1 → XP_038470177.1  beta-parvin isoform X2

    Conserved Domains (2) summary
    cd21336
    Location:84 → 189
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:231 → 360
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  4. XM_038614250.1 → XP_038470178.1  beta-parvin isoform X3

    Conserved Domains (2) summary
    cd21336
    Location:36 → 141
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:183 → 312
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    22513879..22611416 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038550264.1 → XP_038406192.1  beta-parvin isoform X1

    UniProtKB/TrEMBL
    A0A8C0RDJ3, A0A8C0YVL6
    Conserved Domains (2) summary
    cd21336
    Location:89 → 194
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:236 → 365
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  2. XM_038550267.1 → XP_038406195.1  beta-parvin isoform X3

    UniProtKB/TrEMBL
    A0A8C0MBM7
    Conserved Domains (2) summary
    cd21336
    Location:36 → 141
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:183 → 312
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  3. XM_038550265.1 → XP_038406193.1  beta-parvin isoform X2

    UniProtKB/TrEMBL
    A0A8C0MBM7, A0A8C0SBI4, A0A8P0T2V4
    Conserved Domains (2) summary
    cd21336
    Location:84 → 189
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:231 → 360
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  4. XM_038550266.1 → XP_038406194.1  beta-parvin isoform X3

    UniProtKB/TrEMBL
    A0A8C0MBM7
    Conserved Domains (2) summary
    cd21336
    Location:36 → 141
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:183 → 312
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    21492217..21589726 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038637058.1 → XP_038492986.1  beta-parvin isoform X1

    UniProtKB/TrEMBL
    A0A8C0RDJ3, A0A8C0YVL6
    Conserved Domains (2) summary
    cd21336
    Location:89 → 194
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:236 → 365
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  2. XM_038637080.1 → XP_038493008.1  beta-parvin isoform X3

    UniProtKB/TrEMBL
    A0A8C0MBM7
    Conserved Domains (2) summary
    cd21336
    Location:36 → 141
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:183 → 312
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  3. XM_005625762.3 → XP_005625819.3  beta-parvin isoform X2

    UniProtKB/TrEMBL
    A0A8C0MBM7, A0A8C0SBI4, A0A8P0T2V4
    Conserved Domains (2) summary
    cd21336
    Location:84 → 189
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:231 → 360
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin

  4. XM_038637073.1 → XP_038493001.1  beta-parvin isoform X3

    UniProtKB/TrEMBL
    A0A8C0MBM7
    Conserved Domains (2) summary
    cd21336
    Location:36 → 141
    CH_PARVB_rpt1; first calponin homology (CH) domain found in beta-parvin
    cd21338
    Location:183 → 312
    CH_PARVB_rpt2; second calponin homology (CH) domain found in beta-parvin
Nucleotide Protein
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