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HSP90AA1 heat shock protein 90 alpha family class A member 1 [ Canis lupus familiaris (dog) ]

Gene ID: 480438, updated on 5-Mar-2024

Summary

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Official Symbol
HSP90AA1provided by VGNC
Official Full Name
heat shock protein 90 alpha family class A member 1provided by VGNC
Primary source
VGNC:VGNC:50532
See related
Ensembl:ENSCAFG00845005495
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (70369324..70375263, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (69605578..69611507, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (70498429..70504357, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (70033441..70039369, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (70098797..70104717, complement)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene basic proline-rich protein-like Neighboring gene uncharacterized LOC119873029 Neighboring gene uncharacterized LOC106559137 Neighboring gene WD repeat domain 20 Neighboring gene MOK protein kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Geldanamycins exquisitely inhibit HGF/SF-mediated tumor cell invasion. Xie Q, et al. Oncogene, 2005 May 26. PMID 15782129
  2. Heat shock protein 90 is associated with hyperplasia and neoplastic transformation of canine prostatic epithelial cells. Palmieri C, et al. J Comp Pathol, 2014 May. PMID 24679854
  3. Scrib regulates HGF-mediated epithelial morphogenesis and is stabilized by Sgt1-HSP90. Eastburn DJ, et al. J Cell Sci, 2012 Sep 1. PMID 22623728, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent protein folding chaperone IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables disordered domain specific binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to heat IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein stabilization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in myelin sheath IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of protein-containing complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
heat shock protein HSP 90-alpha
Names
heat shock protein 90kDa alpha (cytosolic), class A member 1
XP_038340172.1
XP_038401687.1
XP_038452071.1
XP_038465769.1
XP_038530601.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    70369324..70375263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038674673.1 → XP_038530601.1  heat shock protein HSP 90-alpha

    UniProtKB/TrEMBL
    A0A8C0K8N4, A0A8C0M536, A0A8C0S0X3, A0A8I3MR78
    Related
    ENSCAFP00845007648.1, ENSCAFT00845009784.1
    Conserved Domains (1) summary
    PTZ00272
    Location:18 → 733
    PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    70033441..70039369 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038484244.1 → XP_038340172.1  heat shock protein HSP 90-alpha

    Conserved Domains (1) summary
    PTZ00272
    Location:18 → 733
    PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    70098797..70104717 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038609841.1 → XP_038465769.1  heat shock protein HSP 90-alpha

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    70498429..70504357 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038545759.1 → XP_038401687.1  heat shock protein HSP 90-alpha

    UniProtKB/TrEMBL
    A0A8C0M536
    Conserved Domains (1) summary
    PTZ00272
    Location:18 → 733
    PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    69605578..69611507 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038596143.1 → XP_038452071.1  heat shock protein HSP 90-alpha

    UniProtKB/TrEMBL
    A0A8C0K8N4, A0A8C0M536, A0A8C0S0X3, A0A8I3MR78
    Conserved Domains (1) summary
    PTZ00272
    Location:18 → 733
    PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional
Nucleotide Protein
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