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DTX3L deltex E3 ubiquitin ligase 3L [ Canis lupus familiaris (dog) ]

Gene ID: 478586, updated on 5-Mar-2024

Summary

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Official Symbol
DTX3Lprovided by VGNC
Official Full Name
deltex E3 ubiquitin ligase 3Lprovided by VGNC
Primary source
VGNC:VGNC:40118
See related
Ensembl:ENSCAFG00845023939
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 33
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 33 NC_051837.1 (25911755..25919417)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 33 NC_006615.4 (25700998..25708596)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 33 NC_049254.1 (26309779..26317453)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 33 NC_049293.1 (25708920..25716524)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 33 NC_049774.1 (25752223..25759866)

Chromosome 33 - NC_051837.1Genomic Context describing neighboring genes Neighboring gene karyopherin subunit alpha 1 Neighboring gene uncharacterized LOC119867298 Neighboring gene poly(ADP-ribose) polymerase family member 9 Neighboring gene poly(ADP-ribose) polymerase family member 15 Neighboring gene poly(ADP-ribose) polymerase family member 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase DTX3L
Names
deltex 3-like
XP_005639618.1
XP_038301071.1
XP_038301072.1
XP_038301073.1
XP_038318302.1
XP_038375318.1
XP_038375319.1
XP_038375320.1
XP_038438946.1
XP_038438947.1
XP_038438948.1
XP_038503338.1
XP_038503339.1
XP_038503340.1
XP_535762.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051837.1 Reference ROS_Cfam_1.0

    Range
    25911755..25919417
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038445144.1 → XP_038301072.1  E3 ubiquitin-protein ligase DTX3L isoform X2

    UniProtKB/TrEMBL
    A0A8C0NBB0
    Conserved Domains (3) summary
    COG5540
    Location:373 → 504
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:463 → 503
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:510 → 642
    DTC; Deltex C-terminal domain

  2. XM_038445143.1 → XP_038301071.1  E3 ubiquitin-protein ligase DTX3L isoform X1

    UniProtKB/TrEMBL
    A0A8C0THL0, A0A8I3PVC1, A0A8P0TJZ6
    Related
    ENSCAFP00845033284.1, ENSCAFT00845042460.1
    Conserved Domains (4) summary
    COG5540
    Location:466 → 597
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:556 → 596
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:603 → 735
    DTC; Deltex C-terminal domain
    cl17169
    Location:6 → 83
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. XM_038445145.1 → XP_038301073.1  E3 ubiquitin-protein ligase DTX3L isoform X3

    UniProtKB/TrEMBL
    A0A8C0NBB0
    Conserved Domains (3) summary
    COG5540
    Location:335 → 466
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:425 → 465
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:472 → 604
    DTC; Deltex C-terminal domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049293.1 Alternate UMICH_Zoey_3.1

    Range
    25708920..25716524
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038519391.1 → XP_038375319.1  E3 ubiquitin-protein ligase DTX3L isoform X2

    Conserved Domains (3) summary
    COG5540
    Location:373 → 504
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:463 → 503
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:510 → 642
    DTC; Deltex C-terminal domain

  2. XM_038519390.1 → XP_038375318.1  E3 ubiquitin-protein ligase DTX3L isoform X1

    Conserved Domains (4) summary
    COG5540
    Location:466 → 597
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:556 → 596
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:603 → 735
    DTC; Deltex C-terminal domain
    cl17169
    Location:6 → 83
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. XM_038519392.1 → XP_038375320.1  E3 ubiquitin-protein ligase DTX3L isoform X3

    Conserved Domains (3) summary
    COG5540
    Location:335 → 466
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:425 → 465
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:472 → 604
    DTC; Deltex C-terminal domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049774.1 Alternate UNSW_CanFamBas_1.0

    Range
    25752223..25759866
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038647411.1 → XP_038503339.1  E3 ubiquitin-protein ligase DTX3L isoform X2

    Conserved Domains (3) summary
    COG5540
    Location:373 → 504
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:463 → 503
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:510 → 642
    DTC; Deltex C-terminal domain

  2. XM_038647410.1 → XP_038503338.1  E3 ubiquitin-protein ligase DTX3L isoform X1

    Conserved Domains (4) summary
    COG5540
    Location:466 → 597
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:556 → 596
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:603 → 735
    DTC; Deltex C-terminal domain
    cl17169
    Location:6 → 83
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. XM_038647412.1 → XP_038503340.1  E3 ubiquitin-protein ligase DTX3L isoform X3

    Conserved Domains (3) summary
    COG5540
    Location:335 → 466
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:425 → 465
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:472 → 604
    DTC; Deltex C-terminal domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049254.1 Alternate UU_Cfam_GSD_1.0

    Range
    26309779..26317453
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038583019.1 → XP_038438947.1  E3 ubiquitin-protein ligase DTX3L isoform X2

    UniProtKB/TrEMBL
    A0A8C0NBB0
    Conserved Domains (3) summary
    COG5540
    Location:373 → 504
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:463 → 503
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:510 → 642
    DTC; Deltex C-terminal domain

  2. XM_038583018.1 → XP_038438946.1  E3 ubiquitin-protein ligase DTX3L isoform X1

    UniProtKB/TrEMBL
    A0A8C0THL0, A0A8I3PVC1, A0A8P0TJZ6
    Conserved Domains (4) summary
    COG5540
    Location:466 → 597
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:556 → 596
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:603 → 735
    DTC; Deltex C-terminal domain
    cl17169
    Location:6 → 83
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. XM_038583020.1 → XP_038438948.1  E3 ubiquitin-protein ligase DTX3L isoform X3

    UniProtKB/TrEMBL
    A0A8C0NBB0
    Conserved Domains (3) summary
    COG5540
    Location:335 → 466
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:425 → 465
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:472 → 604
    DTC; Deltex C-terminal domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006615.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    25700998..25708596
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005639561.4 → XP_005639618.1  E3 ubiquitin-protein ligase DTX3L isoform X2

    UniProtKB/TrEMBL
    A0A8C0NBB0
    Conserved Domains (3) summary
    COG5540
    Location:373 → 504
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:463 → 503
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:510 → 642
    DTC; Deltex C-terminal domain

  2. XM_535762.6 → XP_535762.2  E3 ubiquitin-protein ligase DTX3L isoform X1

    UniProtKB/TrEMBL
    A0A8C0THL0, A0A8I3PVC1, A0A8P0TJZ6
    Conserved Domains (4) summary
    COG5540
    Location:466 → 597
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:556 → 596
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:603 → 735
    DTC; Deltex C-terminal domain
    cl17169
    Location:6 → 83
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. XM_038462374.1 → XP_038318302.1  E3 ubiquitin-protein ligase DTX3L isoform X3

    UniProtKB/TrEMBL
    A0A8C0NBB0
    Conserved Domains (3) summary
    COG5540
    Location:335 → 466
    COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16712
    Location:425 → 465
    RING-HC_DTX3L; RING finger, HC subclass, found in protein Deltex-3-like (DTX3L) and similar proteins
    pfam18102
    Location:472 → 604
    DTC; Deltex C-terminal domain
Nucleotide Protein
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