TAS1R2 taste 1 receptor member 2 [Canis lupus familiaris (dog)] - Gene

Summary

Gene symbol: TAS1R2
Gene description: taste 1 receptor member 2
See related: Ensembl:ENSCAFG00845003708
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	2	NC_051806.1 (80343207..80362328)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	2	NC_006584.4 (76234023..76252894)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	2	NC_049223.1 (79183320..79202440)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	2	NC_049262.1 (77102522..77121366)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	2	NC_049743.1 (78112656..78131536)

Chromosome 2 - NC_051806.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Both cats and dogs express T1R3 in a subset of intestinal epithelial cells, and dogs, but not cats, express T1R2.
Title: Sodium/glucose cotransporter-1, sweet receptor, and disaccharidase expression in the intestine of the domestic dog and cat: two species of different dietary habit.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables sweet taste receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sensory perception of sweet taste	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of sweet taste receptor complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: taste receptor type 1 member 2

Names: sweet taste receptor T1R2; taste receptor, type 1, member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031819.1 → NP_001026989.1 taste receptor type 1 member 2 precursor

See identical proteins and their annotated locations for NP_001026989.1

Status: PROVISIONAL

Source sequence(s)

AY916758

UniProtKB/Swiss-Prot

Q49HI0

UniProtKB/TrEMBL

A0A8P0NGX7

Related

ENSCAFP00845005281.1, ENSCAFT00845006636.1

Conserved Domains (4) summary

pfam00003
Location:576 → 811

7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR

pfam01094
Location:70 → 453

ANF_receptor; Receptor family ligand binding region

pfam07562
Location:491 → 542

NCD3G; Nine Cysteines Domain of family 3 GPCR

cl10011
Location:27 → 483

Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily