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ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif 6 [ Pan troglodytes (chimpanzee) ]

Gene ID: 471529, updated on 29-Mar-2024

Summary

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Official Symbol
ADAMTS6provided by VGNC
Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif 6provided by VGNC
Primary source
VGNC:VGNC:3894
Locus tag
CK820_G0034288
See related
Ensembl:ENSPTRG00000016927
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (49152088..49491169)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (49567223..49906537)

Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene tripartite motif containing 23 Neighboring gene peptidylprolyl isomerase domain and WD repeat containing 1 Neighboring gene centromere protein K Neighboring gene large ribosomal subunit protein uL18-like Neighboring gene CWC27 spliceosome associated cyclophilin Neighboring gene uncharacterized LOC107974724 Neighboring gene SREK1 interacting protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 6
Names
ADAMTS-6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    49152088..49491169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_526907.7 → XP_526907.2  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X1

    See identical proteins and their annotated locations for XP_526907.2

    UniProtKB/TrEMBL
    A0A2J8L1C0, A0A6D2XT40, H2R5K7
    Related
    ENSPTRP00000048252.1
    Conserved Domains (5) summary
    smart00209
    Location:561 → 613
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:250 → 465
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01562
    Location:43 → 191
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:719 → 829
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1083 → 1115
    PLAC; PLAC (protease and lacunin) domain

  2. XM_063811175.1 → XP_063667245.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X2

  3. XM_024353403.3 → XP_024209171.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X3

    Conserved Domains (5) summary
    smart00209
    Location:410 → 462
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:99 → 314
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01562
    Location:4 → 40
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:568 → 678
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:932 → 964
    PLAC; PLAC (protease and lacunin) domain

RNA

  1. XR_010157222.1 RNA Sequence

Nucleotide Protein
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