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    NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa [ Homo sapiens ]

    Gene ID: 4707, updated on 19-May-2012

    Summary

    Official Symbol
    NDUFB1provided by HGNC
    Official Full Name
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDaprovided by HGNC
    Primary source
    HGNC:7695
    See related
    Ensembl:ENSG00000183648; HPRD:11952; MIM:603837; Vega:OTTHUMG00000171180
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MNLL; CI-MNLL; CI-SGDH

    Genomic context

    Location :
    14q32.12
    Sequence :
    Chromosome: 14; NC_000014.8 (92582467..92588153, complement)
    See NDUFB1 in Epigenomics, MapViewer

    Chromosome 14 - NC_000014.8Genomic Context describing neighboring genes Neighboring gene thyroid hormone receptor interactor 11 Neighboring gene prothymosin, alpha pseudogene 7 Neighboring gene ataxin 3 Neighboring gene cleavage and polyadenylation specific factor 2, 100kDa Neighboring gene solute carrier family 24 (sodium/potassium/calcium exchanger), member 4

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    O75438 Q01844 EWSR1    HPRD  PubMed  
    O75438 Q16718 NDUFA5    HPRD  PubMed  
    BioGRID:110787 BioGRID:108431 EWSR1    BioGRID  PubMed Two-hybrid 
    BioGRID:110787 BioGRID:110778 NDUFA5    BioGRID  PubMed Two-hybrid 

    General gene information

    Markers

    Pathways from BioSystems

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    NADH dehydrogenase (ubiquinone) activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    NADH dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    mitochondrial electron transport, NADH to ubiquinone NAS
    Non-traceable Author Statement
    more info
    PubMed 
    respiratory electron transport chain TAS
    Traceable Author Statement
    more info
     
    small molecule metabolic process TAS
    Traceable Author Statement
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial inner membrane TAS
    Traceable Author Statement
    more info
     
    mitochondrial respiratory chain complex I IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial respiratory chain complex I NAS
    Non-traceable Author Statement
    more info
    PubMed 
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    respiratory chain IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
    Names
    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
    complex I-MNLL
    complex I MNLL subunit
    NADH-ubiquinone oxidoreductase MNLL subunit

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_004545.3NP_004536.2  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

      Status: VALIDATED

      Source sequence(s)
      BM052981, BX476462
      Consensus CDS
      CCDS9901.1
      UniProtKB/Swiss-Prot
      O75438
      Related
      ENSP00000330787, OTTHUMP00000245341, ENST00000329559, OTTHUMT00000412118
      Conserved Domains (1) summary
      pfam08040
      Location:48105
      Blast Score: 269
      NADH_oxidored; MNLL subunit

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000014.8 Reference GRCh37.p5 Primary Assembly

      Range
      92582467..92588153, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000146.1 Alternate HuRef

      Range
      72763625..72769332, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AL121773.5 (36164..41850) None
    genomic CH471061.1 EAW81476.1
      EAW81477.1
      EAW81478.1
      EAW81479.1
    mRNA AF050638.1 AAD42054.1
    mRNA BC009691.1 AAH09691.2
    mRNA BC104672.1 AAI04673.1
    mRNA BC126232.1 AAI26233.1
    mRNA BC126234.1 AAI26235.1
    mRNA BM052981.1 None
    mRNA BX476462.1 None
    mRNA AK316557.2 BAG48175.1
    other-genetic HQ258048.1 ADR82802.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    O75438.1 GenPept UniProtKB/Swiss-Prot:O75438
    Q3MHU6 GenPept UniProtKB/TrEMBL:Q3MHU6

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