These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_029871.1 RefSeqGene
- Range
- 4980..60423
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001030287.3 → NP_001025458.1 cyclic AMP-dependent transcription factor ATF-3 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Both variants 1 and 3 encode the same isoform (1), which represses rather than activates transcription from promoters with ATF-binding elements.
- Source sequence(s)
-
AC092803, AI949953, BC006322, CD638624, CD641946, CD742713
- Consensus CDS
-
CCDS1506.1
- UniProtKB/Swiss-Prot
-
P18847
- Related
- ENSP00000355954, ENST00000366987
- Conserved Domains (1) summary
-
- smart00338
Location:103 – 147
Blast Score: 101
- BRLZ; basic region leucin zipper
-
NM_001040619.2 → NP_001035709.1 cyclic AMP-dependent transcription factor ATF-3 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (4, also known as deltaZip2a) contains an alternate terminal exon, and thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2, also known as deltaZip2) has a distinct and shorter C-terminus, compared to isoform 1. Isoform 2 lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter.
- Source sequence(s)
-
AB078026, AI949953, AL560585, BC006322, CD742713, DB197400
- Consensus CDS
-
CCDS41464.1
- UniProtKB/Swiss-Prot
-
P18847
-
NM_001206484.2 → NP_001193413.2 cyclic AMP-dependent transcription factor ATF-3 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (3) is shorter at the N-terminus, compared to isoform 1. Both variants 5 and 8 encode isoform 3.
- Source sequence(s)
-
AB078026, AI949953, AL560585, BC006322, CD742713, DA589280
- Consensus CDS
-
CCDS58059.1
- UniProtKB/Swiss-Prot
-
P18847
- UniProtKB/TrEMBL
-
Q5VTZ2
- Conserved Domains (1) summary
-
- smart00338
Location:46 – 90
Blast Score: 87
- BRLZ; basic region leucin zipper
-
NM_001206486.2 → NP_001193415.1 cyclic AMP-dependent transcription factor ATF-3 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) differs in the 5' UTR, lacks an in-frame segment of the 5' coding region, and contains an alternate terminal exon, thus differing in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (5, also known as deltaZip2c) has a distinct C-terminus and is shorter than isoform 1.
- Source sequence(s)
-
AB078026, AI949953, AY313927, BC006322, CD742713
- Consensus CDS
-
CCDS55688.1
- UniProtKB/Swiss-Prot
-
P18847
-
NM_001206488.2 → NP_001193417.2 cyclic AMP-dependent transcription factor ATF-3 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (3) is shorter at the N-terminus, compared to isoform 1. Both variants 5 and 8 encode isoform 3.
- Source sequence(s)
-
AI949953, AL560585, BC006322, BI524020, CD742713
- Consensus CDS
-
CCDS58059.1
- UniProtKB/Swiss-Prot
-
P18847
- UniProtKB/TrEMBL
-
Q5VTZ2
- Conserved Domains (1) summary
-
- smart00338
Location:46 – 90
Blast Score: 87
- BRLZ; basic region leucin zipper
-
NM_001674.3 → NP_001665.1 cyclic AMP-dependent transcription factor ATF-3 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1), which represses rather than activates transcription from promoters with ATF-binding elements. Both variants 1 and 3 encode isoform 1.
- Source sequence(s)
-
AI949953, AL560585, BC006322, CD742713
- Consensus CDS
-
CCDS1506.1
- UniProtKB/Swiss-Prot
-
P18847
- Related
- ENSP00000344352, OTTHUMP00000034887, ENST00000341491, OTTHUMT00000089296
- Conserved Domains (1) summary
-
- smart00338
Location:103 – 147
Blast Score: 101
- BRLZ; basic region leucin zipper
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p10 Primary Assembly
Genomic
-
NC_000001.10 Reference GRCh37.p10 Primary Assembly
- Range
- 212738676..212794119
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000133.1 Alternate HuRef
- Range
- 183415472..183470943
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate CHM1_1.0
Genomic
-
NC_018912.1 Alternate CHM1_1.0
- Range
- 219544763..219600296
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the cited
reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links,
or BLAST links (BLink), but may still be retrieved by clicking on their
accession.version below.
-
NM_001206485.1: Suppressed sequence
- Description
- NM_001206485.1: This RefSeq was permanently suppressed because the transcript is incompletely processed.
-
NM_004024.4: Suppressed sequence
- Description
- NM_004024.4: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.