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ARHGAP18 Rho GTPase activating protein 18 [ Pan troglodytes (chimpanzee) ]

Gene ID: 462994, updated on 29-Mar-2024

Summary

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Official Symbol
ARHGAP18provided by VGNC
Official Full Name
Rho GTPase activating protein 18provided by VGNC
Primary source
VGNC:VGNC:2642
Locus tag
CK820_G0000313
See related
Ensembl:ENSPTRG00000018591
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 5 NC_072403.2 (141469011..141603476, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 6 NC_072404.1 (141468434..141601916, complement)

Chromosome 5 - NC_072403.2Genomic Context describing neighboring genes Neighboring gene laminin subunit alpha 2 Neighboring gene bone morphogenetic protein receptor type-1A-like Neighboring gene uncharacterized LOC104006979 Neighboring gene UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2-like Neighboring gene transmembrane protein 244

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of actin filament polymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of small GTPase mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 18

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072403.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    141469011..141603476 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001168191.8 → XP_001168191.2  rho GTPase-activating protein 18

    See identical proteins and their annotated locations for XP_001168191.2

    UniProtKB/TrEMBL
    A0A2J8PTD9, A0A2J8PTE1, A0A6D2XB51, H2QTQ5
    Related
    ENSPTRP00000031735.4
    Conserved Domains (1) summary
    cd04391
    Location:321 → 534
    RhoGAP_ARHGAP18; RhoGAP_ARHGAP18: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their ...
Nucleotide Protein
Heading Accession and Version

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