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CYP39A1 cytochrome P450 family 39 subfamily A member 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 462743, updated on 29-Mar-2024

Summary

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Official Symbol
CYP39A1provided by VGNC
Official Full Name
cytochrome P450 family 39 subfamily A member 1provided by VGNC
Primary source
VGNC:VGNC:6149
Locus tag
CK820_G0007331
See related
Ensembl:ENSPTRG00000018235
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 5 NC_072403.2 (52431572..52534624, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 6 NC_072404.1 (52431577..52534629, complement)

Chromosome 5 - NC_072403.2Genomic Context describing neighboring genes Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 4 Neighboring gene actin, clone 302-like Neighboring gene uncharacterized LOC107975155 Neighboring gene regulator of calcineurin 2 Neighboring gene solute carrier family 25 member 27 Neighboring gene phospholipase A2 group VII Neighboring gene tudor domain containing 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxysterol 7-alpha-hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid 7-alpha-hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bile acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
24-hydroxycholesterol 7-alpha-hydroxylase
Names
cytochrome P450, family 39, subfamily A, polypeptide 1
XP_003311399.1
XP_009449668.1
XP_009449669.1
XP_009449670.1
XP_009449671.1
XP_009449673.2
XP_054541849.1
XP_054541850.1
XP_063669161.1
XP_518518.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072403.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    52431572..52534624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_518518.7 → XP_518518.2  24-hydroxycholesterol 7-alpha-hydroxylase isoform X2

    See identical proteins and their annotated locations for XP_518518.2

    UniProtKB/TrEMBL
    A0A2J8P0P1, A0A6D2X8P2, H2QT44
    Related
    ENSPTRP00000031163.4
    Conserved Domains (1) summary
    cl12078
    Location:35 → 460
    p450; Cytochrome P450

  2. XM_003311351.4 → XP_003311399.1  24-hydroxycholesterol 7-alpha-hydroxylase isoform X5

    Conserved Domains (1) summary
    cl12078
    Location:35 → 440
    p450; Cytochrome P450

  3. XM_054685875.2 → XP_054541850.1  24-hydroxycholesterol 7-alpha-hydroxylase isoform X9

  4. XM_063813091.1 → XP_063669161.1  24-hydroxycholesterol 7-alpha-hydroxylase isoform X10

  5. XM_009451396.4 → XP_009449671.1  24-hydroxycholesterol 7-alpha-hydroxylase isoform X8

    Conserved Domains (1) summary
    cl12078
    Location:35 → 381
    p450; Cytochrome P450

  6. XM_009451394.4 → XP_009449669.1  24-hydroxycholesterol 7-alpha-hydroxylase isoform X4

    Conserved Domains (1) summary
    cl12078
    Location:35 → 397
    p450; Cytochrome P450

  7. XM_054685874.2 → XP_054541849.1  24-hydroxycholesterol 7-alpha-hydroxylase isoform X6

  8. XM_009451393.5 → XP_009449668.1  24-hydroxycholesterol 7-alpha-hydroxylase isoform X1

    UniProtKB/TrEMBL
    A0A2I3SQE5
    Related
    ENSPTRP00000079149.1
    Conserved Domains (1) summary
    cl12078
    Location:35 → 417
    p450; Cytochrome P450

  9. XM_009451395.4 → XP_009449670.1  24-hydroxycholesterol 7-alpha-hydroxylase isoform X7

    Conserved Domains (1) summary
    cl12078
    Location:35 → 421
    p450; Cytochrome P450

  10. XM_009451398.4 → XP_009449673.2  24-hydroxycholesterol 7-alpha-hydroxylase isoform X3

Nucleotide Protein
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