PMS1 PMS1 homolog 1, mismatch repair system component [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PMS1provided by VGNC
Official Full Name: PMS1 homolog 1, mismatch repair system componentprovided by VGNC
Primary source: VGNC:VGNC:2786
Locus tag: CK820_G0053696
See related: Ensembl:ENSPTRG00000012737
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2B

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	13	NC_072411.2 (91848976..91943089)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	2B	NC_072400.1 (91848786..91943062)

Chromosome 13 - NC_072411.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D2S2027 (e-PCR)
- UniSTS:32011

RH93649 (e-PCR)
- UniSTS:86159

GDB:581629 (e-PCR)
- UniSTS:157859

G67579 (e-PCR)
- UniSTS:207035

G67582 (e-PCR)
- UniSTS:207037

G67535 (e-PCR)
- UniSTS:207038

G67580 (e-PCR)
- UniSTS:207039

SGC38239 (e-PCR)
- UniSTS:23803

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP-dependent DNA damage sensor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables mismatched DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in mismatch repair	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of MutLalpha complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: PMS1 protein homolog 1

Names: PMS1 postmeiotic segregation increased 1; postmeiotic segregation 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

91848976..91943089

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016950181.4 → XP_016805670.1 PMS1 protein homolog 1 isoform X1

UniProtKB/TrEMBL

A0A2I3RPI6, A0A2J8IS33, A0A6D2WE62

Conserved Domains (2) summary

cd01390
Location:572 → 636

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

TIGR00585
Location:1 → 318

mutl; DNA mismatch repair protein MutL
XM_063791347.1 → XP_063647417.1 PMS1 protein homolog 1 isoform X5

UniProtKB/TrEMBL

A0A2I3S275, A0A2J8IS65, A0A6D2WX72
XM_009443875.5 → XP_009442150.1 PMS1 protein homolog 1 isoform X1

See identical proteins and their annotated locations for XP_009442150.1

UniProtKB/TrEMBL

A0A2I3RPI6, A0A2J8IS33, A0A6D2WE62

Conserved Domains (2) summary

cd01390
Location:572 → 636

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

TIGR00585
Location:1 → 318

mutl; DNA mismatch repair protein MutL
XM_063791340.1 → XP_063647410.1 PMS1 protein homolog 1 isoform X3
XM_063791355.1 → XP_063647425.1 PMS1 protein homolog 1 isoform X6

UniProtKB/TrEMBL

A0A2J8IS23
XM_063791338.1 → XP_063647408.1 PMS1 protein homolog 1 isoform X2

UniProtKB/TrEMBL

A0A2J8IS49, A0A6D2WMT7, H2QJ52, K7C7R8
XM_063791346.1 → XP_063647416.1 PMS1 protein homolog 1 isoform X4
XM_016950174.4 → XP_016805663.1 PMS1 protein homolog 1 isoform X1

UniProtKB/TrEMBL

A0A2I3RPI6, A0A2J8IS33, A0A6D2WE62

Related

ENSPTRP00000066616.1

Conserved Domains (2) summary

cd01390
Location:572 → 636

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

TIGR00585
Location:1 → 318

mutl; DNA mismatch repair protein MutL
XM_016950180.4 → XP_016805669.1 PMS1 protein homolog 1 isoform X1

UniProtKB/TrEMBL

A0A2I3RPI6, A0A2J8IS33, A0A6D2WE62

Conserved Domains (2) summary

cd01390
Location:572 → 636

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

TIGR00585
Location:1 → 318

mutl; DNA mismatch repair protein MutL
XM_016950186.4 → XP_016805675.1 PMS1 protein homolog 1 isoform X5

UniProtKB/TrEMBL

A0A2I3S275, A0A2J8IS65, A0A6D2WX72

Related

ENSPTRP00000071087.1

Conserved Domains (2) summary

cd01390
Location:572 → 617

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

TIGR00585
Location:1 → 318

mutl; DNA mismatch repair protein MutL
XM_063791353.1 → XP_063647423.1 PMS1 protein homolog 1 isoform X6

UniProtKB/TrEMBL

A0A2J8IS23
XM_016950177.4 → XP_016805666.1 PMS1 protein homolog 1 isoform X1

UniProtKB/TrEMBL

A0A2I3RPI6, A0A2J8IS33, A0A6D2WE62

Conserved Domains (2) summary

cd01390
Location:572 → 636

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

TIGR00585
Location:1 → 318

mutl; DNA mismatch repair protein MutL
XM_063791339.1 → XP_063647409.1 PMS1 protein homolog 1 isoform X3
XM_063791352.1 → XP_063647422.1 PMS1 protein homolog 1 isoform X6

UniProtKB/TrEMBL

A0A2J8IS23
XM_063791343.1 → XP_063647413.1 PMS1 protein homolog 1 isoform X4
XM_063791357.1 → XP_063647427.1 PMS1 protein homolog 1 isoform X8

UniProtKB/TrEMBL

A0A2I3S279, A0A2J8IS30, A0A6D2WDF3
XM_063791344.1 → XP_063647414.1 PMS1 protein homolog 1 isoform X4
XM_024354976.3 → XP_024210744.1 PMS1 protein homolog 1 isoform X1

UniProtKB/TrEMBL

A0A2I3RPI6, A0A2J8IS33, A0A6D2WE62

Conserved Domains (2) summary

cd01390
Location:572 → 636

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

TIGR00585
Location:1 → 318

mutl; DNA mismatch repair protein MutL
XM_063791351.1 → XP_063647421.1 PMS1 protein homolog 1 isoform X6

UniProtKB/TrEMBL

A0A2J8IS23
XM_054680004.2 → XP_054535979.1 PMS1 protein homolog 1 isoform X8

UniProtKB/TrEMBL

A0A2I3S279, A0A2J8IS30, A0A6D2WDF3
XM_016950178.4 → XP_016805667.1 PMS1 protein homolog 1 isoform X1

UniProtKB/TrEMBL

A0A2I3RPI6, A0A2J8IS33, A0A6D2WE62

Conserved Domains (2) summary

cd01390
Location:572 → 636

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

TIGR00585
Location:1 → 318

mutl; DNA mismatch repair protein MutL
XM_016950183.4 → XP_016805672.1 PMS1 protein homolog 1 isoform X3
XM_016950182.4 → XP_016805671.1 PMS1 protein homolog 1 isoform X2

UniProtKB/TrEMBL

A0A2J8IS49, A0A6D2WMT7, H2QJ52, K7C7R8

Related

ENSPTRP00000021775.4

Conserved Domains (2) summary

cd01390
Location:533 → 597

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

TIGR00585
Location:1 → 279

mutl; DNA mismatch repair protein MutL
XM_016950190.4 → XP_016805679.1 PMS1 protein homolog 1 isoform X7

UniProtKB/TrEMBL

A0A2J8IS44
XM_063791349.1 → XP_063647419.1 PMS1 protein homolog 1 isoform X6

UniProtKB/TrEMBL

A0A2J8IS23
XM_063791342.1 → XP_063647412.1 PMS1 protein homolog 1 isoform X4
XM_016950191.4 → XP_016805680.1 PMS1 protein homolog 1 isoform X8

UniProtKB/TrEMBL

A0A2I3S279, A0A2J8IS30, A0A6D2WDF3

Related

ENSPTRP00000071043.1

Conserved Domains (1) summary

TIGR00585
Location:1 → 140

mutl; DNA mismatch repair protein MutL
XM_063791337.1 → XP_063647407.1 PMS1 protein homolog 1 isoform X2

UniProtKB/TrEMBL

A0A2J8IS49, A0A6D2WMT7, H2QJ52, K7C7R8
XM_063791345.1 → XP_063647415.1 PMS1 protein homolog 1 isoform X4
XM_016950175.4 → XP_016805664.1 PMS1 protein homolog 1 isoform X1

UniProtKB/TrEMBL

A0A2I3RPI6, A0A2J8IS33, A0A6D2WE62

Conserved Domains (2) summary

cd01390
Location:572 → 636

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

TIGR00585
Location:1 → 318

mutl; DNA mismatch repair protein MutL
XM_063791336.1 → XP_063647406.1 PMS1 protein homolog 1 isoform X2

UniProtKB/TrEMBL

A0A2J8IS49, A0A6D2WMT7, H2QJ52, K7C7R8
XM_063791350.1 → XP_063647420.1 PMS1 protein homolog 1 isoform X6

UniProtKB/TrEMBL

A0A2J8IS23
XM_016950179.4 → XP_016805668.1 PMS1 protein homolog 1 isoform X1

UniProtKB/TrEMBL

A0A2I3RPI6, A0A2J8IS33, A0A6D2WE62

Conserved Domains (2) summary

cd01390
Location:572 → 636

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

TIGR00585
Location:1 → 318

mutl; DNA mismatch repair protein MutL
XM_063791356.1 → XP_063647426.1 PMS1 protein homolog 1 isoform X6

UniProtKB/TrEMBL

A0A2J8IS23
XM_063791341.1 → XP_063647411.1 PMS1 protein homolog 1 isoform X3
XM_063791354.1 → XP_063647424.1 PMS1 protein homolog 1 isoform X6

UniProtKB/TrEMBL

A0A2J8IS23
XM_016950188.4 → XP_016805677.1 PMS1 protein homolog 1 isoform X6

UniProtKB/TrEMBL

A0A2J8IS23, G2HFB2

Conserved Domains (2) summary

cd01390
Location:396 → 460

HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

cd03485
Location:29 → 162

MutL_Trans_hPMS_1_like; MutL_Trans_hPMS1_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM1 (hPSM1) and yeast MLH2. hPSM1 and yMLH2 are members of the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is ...