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    MUC1 mucin 1, cell surface associated [ Homo sapiens (human) ]

    Gene ID: 4582, updated on 12-May-2013
    Official Symbol
    MUC1provided by HGNC
    Official Full Name
    mucin 1, cell surface associatedprovided by HGNC
    Primary source
    HGNC:7508
    Locus tag
    RP11-263K19.2
    See related
    Ensembl:ENSG00000185499; HPRD:01152; MIM:158340; Vega:OTTHUMG00000035681
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    EMA; PEM; PUM; KL-6; MAM6; PEMT; CD227; H23AG; MUC-1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC
    Summary
    This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
    Location :
    1q21
    Sequence :
    Chromosome: 1; NC_000001.10 (155158300..155162706, complement)
    See MUC1 in Epigenomics, MapViewer

    Chromosome 1 - NC_000001.10Genomic Context describing neighboring genes Neighboring gene keratinocyte associated protein 2 Neighboring gene tripartite motif containing 46 Neighboring gene microRNA 92b Neighboring gene thrombospondin 3

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description
    NP_002447.3 U17193.1 BAX    BIND  PubMed MUC1 C-ter interacts with the Bax promoter. 
    NP_002447.3 U24170.1 CDKN1A    BIND  PubMed MUC1 C-ter interacts with the p21 promoter. 
    NP_002447.3 NP_000537.2 TP53    BIND  PubMed MUC1 C-ter interacts with p53. 
    NP_877418.1 NP_001895.1 CTNNB1    BIND  PubMed MUC1 interacts with beta-catenin. 
    NP_877418.1 NP_005219.2 EGFR    BIND  PubMed MUC1 interacts with and is tyrosine-phosphorylated by EGFR. 
    NP_877418.1 NP_005408.1 SRC    BIND  PubMed MUC1 interacts with c-Src. 
    P15941 P00519 ABL1    HPRD  PubMed  
    P15941 P25054 APC    HPRD  PubMed  
    P15941 NP_001895.1 CTNNB1    HPRD  PubMed  
    P15941 P35222 CTNNB1    HPRD  PubMed  
    P15941 NP_001322.1 CTNND1    HPRD  PubMed  
    P15941 O60716 CTNND1    HPRD  PubMed  
    P15941 NP_005219.1 EGFR    HPRD  PubMed  
    P15941 P00533 EGFR    HPRD  PubMed  
    P15941 NP_004439.1 ERBB2    HPRD  PubMed  
    P15941 P04626 ERBB2    HPRD  PubMed  
    P15941 NP_001973.1 ERBB3    HPRD  PubMed  
    P15941 P21860 ERBB3    HPRD  PubMed  
    P15941 NP_005226.1 ERBB4    HPRD  PubMed  
    P15941 Q15303 ERBB4    HPRD  PubMed  
    P15941 GalNAc Transferase 1 GALNT1    HPRD  PubMed  
    P15941 Q10472 GALNT1    HPRD  PubMed  
    P15941 NP_938080.1 GALNT10    HPRD  PubMed  
    P15941 Q86SR1 GALNT10    HPRD  PubMed  
    P15941 Q8IXK2 GALNT12    HPRD  PubMed  
    P15941 NP_473451.2 GALNT15    HPRD  PubMed  
    P15941 Q8N3T1 GALNT15    HPRD  PubMed  
    P15941 NP_004472.1 GALNT2    HPRD  PubMed  
    P15941 Q10471 GALNT2    HPRD  PubMed  
    P15941 NP_002077.1 GRB2    HPRD  PubMed  
    P15941 P62993 GRB2    HPRD  PubMed  
    P15941 NP_002084.2 GSK3B    HPRD  PubMed  
    P15941 P49841 GSK3B    HPRD  PubMed  
    P15941 NP_002221.1 JUP    HPRD  PubMed  
    P15941 P14923 JUP    HPRD  PubMed  
    P15941 P06239 LCK    HPRD  PubMed  
    P15941 P07948 LYN    HPRD  PubMed  
    P15941 NP_060277.1 OSGEP    HPRD  PubMed  
    P15941 Q9NPF4 OSGEP    HPRD  PubMed  
    P15941 NP_006245.1 PRKCD    HPRD  PubMed  
    P15941 Q05655 PRKCD    HPRD  PubMed  
    P15941 Q9BZZ2 SIGLEC1    HPRD  PubMed  
    P15941 NP_005624.2 SOS1    HPRD  PubMed  
    P15941 Q07889 SOS1    HPRD  PubMed  
    P15941 NP_005408.1 SRC    HPRD  PubMed  
    P15941 P12931 SRC    HPRD  PubMed  
    P15941 P43403 ZAP70    HPRD  PubMed  
    BioGRID:110669 BioGRID:106543 ABL1    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity 
    BioGRID:110669 BioGRID:106821 APC    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:110669 BioGRID:107880 CTNNB1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:110669 BioGRID:107881 CTNND1    BioGRID  PubMed Affinity Capture-Western; Co-localization; Reconstituted Complex 
    BioGRID:110669 BioGRID:198512 Ctnnb1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:110669 BioGRID:108276 EGFR    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity 
    BioGRID:110669 BioGRID:108376 ERBB2    BioGRID  PubMed Affinity Capture-Western; Co-localization 
    BioGRID:110669 BioGRID:108377 ERBB3    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:110669 BioGRID:108378 ERBB4    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:110669 BioGRID:108403 ESR1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:110669 BioGRID:122816 GALNT12    BioGRID  PubMed Biochemical Activity 
    BioGRID:110669 BioGRID:114240 GALNT4    BioGRID  PubMed Biochemical Activity 
    BioGRID:110669 BioGRID:109142 GRB2    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex; Two-hybrid 
    BioGRID:110669 BioGRID:109187 GSK3B    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:110669 BioGRID:109767 IKBKB    BioGRID  PubMed Affinity Capture-Western; Co-fractionation 
    BioGRID:110669 BioGRID:114089 IKBKG    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:110669 BioGRID:109928 JUN    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:110669 BioGRID:109931 JUP    BioGRID  PubMed Affinity Capture-Western; Co-localization 
    BioGRID:110669 BioGRID:110245 LYN    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:110669 BioGRID:111566 PRKCD    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity; Reconstituted Complex 
    BioGRID:110669 BioGRID:112537 SOS1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:110669 BioGRID:112592 SRC    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity; Reconstituted Complex 
    BioGRID:110669 BioGRID:112771 TBP    BioGRID  PubMed Co-localization 
    BioGRID:110669 BioGRID:112986 TNFRSF1A    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:110669 BioGRID:113010 TP53    BioGRID  PubMed Affinity Capture-Western; Co-localization; Reconstituted Complex 
    • IL-7 Signaling Pathway, organism-specific biosystem (from WikiPathways)
      IL-7 Signaling Pathway, organism-specific biosystemInterleukin-7 belongs to a family of cytokines, which includes IL-2, IL-4, IL-9, IL-15 and IL-21. It signals through a receptor complex consisting of IL-7 receptor alpha chain (IL7RA) and a common ga...
    • Metabolism of proteins, organism-specific biosystem (from REACTOME)
      Metabolism of proteins, organism-specific biosystemProtein metabolism comprises the pathways of translation, post-translational modification and protein folding.
    • O-linked glycosylation of mucins, organism-specific biosystem (from REACTOME)
      O-linked glycosylation of mucins, organism-specific biosystemMucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most metazoa. Mucins' key characteristic is their ability to form gels...
    • Post-translational protein modification, organism-specific biosystem (from REACTOME)
      Post-translational protein modification, organism-specific biosystemAfter translation, many newly formed proteins undergo further covalent modifications that alter their functional properties and that are essentially irreversible under physiological conditions in the...
    • Termination of O-glycan biosynthesis, organism-specific biosystem (from REACTOME)
      Termination of O-glycan biosynthesis, organism-specific biosystemO-glycan biosynthesis can be terminated (or modified) by the addition of sialic acid residues on Core 1 and 2 glycoproteins by sialyltransferases (Varki et al, 2009).

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    RNA polymerase II core promoter proximal region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    p53 binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
     
    transcription cofactor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi lumen TAS
    Traceable Author Statement
    more info
     
    apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    integral to plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    nuclear chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    mucin-1
    Names
    mucin-1
    episialin
    DF3 antigen
    H23 antigen
    cancer antigen 15-3
    krebs von den Lungen-6
    mucin 1, transmembrane
    tumor-associated mucin
    carcinoma-associated mucin
    polymorphic epithelial mucin
    peanut-reactive urinary mucin
    tumor associated epithelial mucin
    breast carcinoma-associated antigen DF3
    tumor-associated epithelial membrane antigen

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029383.1 RefSeqGene

      Range
      5001..9407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018016.2NP_001018016.1  mucin-1 isoform 2 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) uses alternate in-frame splice sites for two exons, compared to variant 1. The resulting isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AA425062, BC120975, J05581
      Consensus CDS
      CCDS30882.1
      UniProtKB/Swiss-Prot
      P15941
      UniProtKB/TrEMBL
      Q0VAP5
      Related
      ENSP00000357377, OTTHUMP00000033787, ENST00000368392, OTTHUMT00000086736
      Conserved Domains (1) summary
      smart00200
      Location:45161
      Blast Score: 290
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    2. NM_001018017.2NP_001018017.1  mucin-1 isoform 3 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site, compared to variant 1. The resulting isoform (3) is shorter than isoform 1.
      Source sequence(s)
      AA425062, AL713999, BC120974, J05581
      Consensus CDS
      CCDS30883.1
      UniProtKB/Swiss-Prot
      P15941
      Conserved Domains (1) summary
      smart00200
      Location:36152
      Blast Score: 290
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    3. NM_001044390.2NP_001037855.1  mucin-1 isoform 5 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) has multiple differences which result in a frameshift in the central coding region, compared to variant 1. These differences result in a shorter isoform (5), compared to isoform 1.
      Source sequence(s)
      AA425062, AL713999, AY327582, J05581
      Consensus CDS
      CCDS41409.1
      UniProtKB/Swiss-Prot
      P15941
    4. NM_001044391.2NP_001037856.1  mucin-1 isoform 6 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) has multiple differences but maintains the reading frame, compared to variant 1. These differences result in a shorter isoform (6), compared to isoform 1.
      Source sequence(s)
      AA425062, AL713999, AY327583, J05581
      UniProtKB/Swiss-Prot
      P15941
      UniProtKB/TrEMBL
      Q7Z551
      Conserved Domains (2) summary
      cl00944
      Location:110145
      Blast Score: 78
      KdpC; K+-transporting ATPase, c chain
      cl02507
      Location:3676
      Blast Score: 99
      SEA; SEA domain
    5. NM_001044392.2NP_001037857.1  mucin-1 isoform 7 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) has multiple differences but maintains the reading frame, compared to variant 1. These differences result in a shorter isoform (7), compared to isoform 1.
      Source sequence(s)
      AA425062, AL713999, AY327584, J05581
      Consensus CDS
      CCDS41408.1
      UniProtKB/Swiss-Prot
      P15941
      UniProtKB/TrEMBL
      Q7Z550
      Conserved Domains (2) summary
      cl00944
      Location:119154
      Blast Score: 78
      KdpC; K+-transporting ATPase, c chain
      cl02507
      Location:4585
      Blast Score: 99
      SEA; SEA domain
    6. NM_001044393.2NP_001037858.1  mucin-1 isoform 8 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) lacks an exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (8) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AA425062, AL713999, AY327598, J05581
      UniProtKB/Swiss-Prot
      P15941
      UniProtKB/TrEMBL
      Q7Z538
    7. NM_001204285.1NP_001191214.1  mucin-1 isoform 9 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) has multiple differences but maintains the reading frame, compared to variant 1. The encoded isoform (9) is longer than isoform 1.
      Source sequence(s)
      AA425062, AL713999, J05581
      Consensus CDS
      CCDS55640.1
      UniProtKB/TrEMBL
      B1AVQ5
      UniProtKB/Swiss-Prot
      P15941
      Related
      ENSP00000357380, OTTHUMP00000033786, ENST00000368395, OTTHUMT00000086735
      Conserved Domains (1) summary
      smart00200
      Location:254372
      Blast Score: 350
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    8. NM_001204286.1NP_001191215.1  mucin-1 isoform 10 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) has multiple differences but maintains the reading frame, compared to variant 1. The encoded isoform (10) is longer than isoform 1.
      Source sequence(s)
      AA425062, AH001451, AL713999, J05581
      UniProtKB/Swiss-Prot
      P15941
      Conserved Domains (1) summary
      smart00200
      Location:263381
      Blast Score: 350
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    9. NM_001204287.1NP_001191216.1  mucin-1 isoform 11 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) uses an alternate splice site, compared to variant 1. The encoded isoform (11) is longer than isoform 1.
      Source sequence(s)
      AA425062, EF583647, J05581
      UniProtKB/TrEMBL
      A5YRU5
      UniProtKB/Swiss-Prot
      P15941
      Conserved Domains (1) summary
      smart00200
      Location:64179
      Blast Score: 332
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    10. NM_001204288.1NP_001191217.1  mucin-1 isoform 12 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) has multiple differences, one of which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (12) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AA425062, EF583649, J05581
      UniProtKB/TrEMBL
      A5YRU7
      UniProtKB/Swiss-Prot
      P15941
      Conserved Domains (1) summary
      smart00200
      Location:45150
      Blast Score: 268
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    11. NM_001204289.1NP_001191218.1  mucin-1 isoform 13 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13) has multiple differences but maintains the reading frame, compared to variant 1. The encoded isoform (13) is shorter than isoform 1.
      Source sequence(s)
      AA425062, AL713999, EF583652, J05581
      UniProtKB/TrEMBL
      A5YRV0
      UniProtKB/Swiss-Prot
      P15941
      Related
      ENSP00000343482, ENST00000338684
      Conserved Domains (1) summary
      cl02507
      Location:63135
      Blast Score: 188
      SEA; SEA domain
    12. NM_001204290.1NP_001191219.1  mucin-1 isoform 14 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14) has multiple differences but maintains the reading frame, compared to variant 1. The encoded isoform (14) is shorter than isoform 1.
      Source sequence(s)
      AA425062, EF583654, J05581
      UniProtKB/TrEMBL
      A5YRV2
      UniProtKB/Swiss-Prot
      P15941
      Conserved Domains (1) summary
      cl02507
      Location:42114
      Blast Score: 187
      SEA; SEA domain
    13. NM_001204291.1NP_001191220.1  mucin-1 isoform 15 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15) has multiple differences but maintains the reading frame, compared to variant 1. The encoded isoform (15) is shorter than isoform 1.
      Source sequence(s)
      AA425062, AL713999, EF670708, J05581
      UniProtKB/TrEMBL
      A6ZID6
      UniProtKB/Swiss-Prot
      P15941
      Conserved Domains (1) summary
      smart00200
      Location:62138
      Blast Score: 197
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    14. NM_001204292.1NP_001191221.1  mucin-1 isoform 16 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16) has multiple differences compared to variant 1, one of which results in a translational frameshift in the central coding region. The encoded isoform (16) is shorter than isoform 1.
      Source sequence(s)
      AA425062, AL713999, EF670709, J05581
      UniProtKB/TrEMBL
      A6ZID7
      UniProtKB/Swiss-Prot
      P15941
      Conserved Domains (1) summary
      cl02507
      Location:80136
      Blast Score: 153
      SEA; SEA domain
    15. NM_001204293.1NP_001191222.1  mucin-1 isoform 17 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17) lacks an exon in the 3' coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (17) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AA425062, AL713999, EF670711, J05581
      Consensus CDS
      CCDS55642.1
      UniProtKB/TrEMBL
      A6ZID9
      UniProtKB/Swiss-Prot
      P15941
      Related
      ENSP00000357378, ENST00000368393
      Conserved Domains (1) summary
      smart00200
      Location:55158
      Blast Score: 301
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    16. NM_001204294.1NP_001191223.1  mucin-1 isoform 18 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18) has multiple differences compared to variant 1, one of which results in a translational frameshift in the central coding region. The encoded isoform (18) is shorter than isoform 1.
      Source sequence(s)
      AA425062, AL713999, EF670712, J05581
      Consensus CDS
      CCDS55641.1
      UniProtKB/TrEMBL
      A6ZIE0
      UniProtKB/Swiss-Prot
      P15941
      Conserved Domains (1) summary
      cl02507
      Location:71127
      Blast Score: 153
      SEA; SEA domain
    17. NM_001204295.1NP_001191224.1  mucin-1 isoform 19 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19) has multiple differences but maintains the reading frame, compared to variant 1. These differences result in a shorter isoform (19), compared to isoform 1.
      Source sequence(s)
      AA425062, AL713999, EF670716, J05581
      UniProtKB/TrEMBL
      A6ZIE4
      UniProtKB/Swiss-Prot
      P15941
      Conserved Domains (1) summary
      cl02507
      Location:4585
      Blast Score: 101
      SEA; SEA domain
    18. NM_001204296.1NP_001191225.1  mucin-1 isoform 20 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20) has multiple differences compared to variant 1, one of which results in a translational frameshift in the central coding region. The encoded isoform (20) is shorter than isoform 1.
      Source sequence(s)
      AA425062, FJ226053, J05581
      UniProtKB/TrEMBL
      B6ECB3
      UniProtKB/Swiss-Prot
      P15941
    19. NM_001204297.1NP_001191226.1  mucin-1 isoform 21 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21) has multiple differences but maintains the reading frame, compared to variant 1. These differences result in a shorter isoform (21), compared to isoform 1.
      Source sequence(s)
      AA425062, EF670718, J05581
      UniProtKB/TrEMBL
      A6ZIE6
      UniProtKB/Swiss-Prot
      P15941
      Conserved Domains (1) summary
      cl02507
      Location:64103
      Blast Score: 143
      SEA; SEA domain
    20. NM_002456.5NP_002447.4  mucin-1 isoform 1 precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents isoform 1.
      Source sequence(s)
      AA425062, AL713999, J05581, U60261
      Consensus CDS
      CCDS1098.1
      UniProtKB/Swiss-Prot
      P15941
      Conserved Domains (1) summary
      smart00200
      Location:55170
      Blast Score: 332
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 104

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p10 Primary Assembly

    Genomic

    1. NC_000001.10 Reference GRCh37.p10 Primary Assembly

      Range
      155158300..155162706, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000133.1 Alternate HuRef

      Range
      126521570..126525810, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.0

    Genomic

    1. NC_018912.1 Alternate CHM1_1.0

      Range
      161660317..161664059, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001018021.1: Suppressed sequence

      Description
      NM_001018021.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    2. NM_182741.1: Suppressed sequence

      Description
      NM_182741.1: This RefSeq was permanently suppressed because currently there is insufficient support from non-cancerous tissues for the transcript and protein.

      Supplemental Content

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