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    net [ Drosophila melanogaster ]

    Gene ID: 45339, updated on 10-May-2012
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    Summary

    Official Symbol
    netprovided by Flybase
    Primary source
    FLYBASE:FBgn0002931
    Locus tag
    Dmel_CG11450
    Gene type
    protein coding
    RNA name
    net
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    bHLHc42; CG11450; Dmel\CG11450; Group IId; shout; Shout
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    Genomic context

    Location :
    21B1-21B1; 2-0.0 cM
    Sequence :
    Chromosome: 2L; NT_033779.4 (82456..87382, complement)
    See net in Epigenomics, MapViewer

    Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene CG11372 gene product from transcript CG11372-RD Neighboring gene CG11374 gene product from transcript CG11374-RC Neighboring gene CG11376 gene product from transcript CG11376-RA Neighboring gene CG11377 gene product from transcript CG11377-RA Neighboring gene Na[+]/H[+] hydrogen exchanger 1

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. RNAi experiments in D. melanogaster: solutions to the overlooked problem of off-targets shared by independent dsRNAs. Seinen E, et al. PLoS One, 2010 Oct 1. PMID 20957038.
    2. Bap170, a subunit of the Drosophila PBAP chromatin remodeling complex, negatively regulates the EGFR signaling. Rendina R, et al. Genetics, 2010 Sep. PMID 20551433.
    3. Identification of genes affecting wing patterning through a loss-of-function mutagenesis screen and characterization of med15 function during wing development. Terriente-Félix A, et al. Genetics, 2010 Jun. PMID 20233856.
    4. Transcriptional targets of Drosophila JAK/STAT pathway signalling as effectors of haematopoietic tumour formation. Bina S, et al. EMBO Rep, 2010 Mar. PMID 20168330.
    5. Osa, a subunit of the BAP chromatin-remodelling complex, participates in the regulation of gene expression in response to EGFR signalling in the Drosophila wing. Terriente-Félix A, et al. Dev Biol, 2009 May 15. PMID 19306864.

    See all (49) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Previous results indicated that netrin phenotype is epistatic to sli or robo phenotypes. However, it seems likely that this previously reported epistatic relationship might be due to the partial penetrance of the sli, robo, robo3 (or robo2) phenotypes.
      Title: Regulation of axon guidance by slit and netrin signaling in the Drosophila ventral nerve cord.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:69604 BioGRID:63083 Egfr    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:69604 BioGRID:67421 H    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:69604 BioGRID:59275 Mer    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:69604 BioGRID:63646 emc    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:69604 BioGRID:64316 nmo    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:69604 BioGRID:63708 rho    BioGRID  PubMed Phenotypic Suppression 
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    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    sequence-specific DNA binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    imaginal disc-derived wing vein morphogenesis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    imaginal disc-derived wing vein specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    negative regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    regulation of transcription, DNA-dependent ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    nucleus NAS
    Non-traceable Author Statement
    more info
    		  
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    General protein information

    Preferred Names
    CG11450 gene product from transcript CG11450-RB
    Names
    CG11450-PB
    net
    net-PB
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.4

      Range
      82456..87382, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080081.2 → NP_524820.2  net [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPI8
      Related
      FBpp0288762, FBtr0290323
      Conserved Domains (1) summary
      cl00081
      Location:281 – 326
      Blast Score: 107
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014134.5 AAF51562.3
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    Additional Links

    Gene LinkOut

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