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    EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 453321, updated on 11-May-2013
    Gene symbol
    EIF2AK4
    Gene description
    eukaryotic translation initiation factor 2 alpha kinase 4
    See related
    Ensembl:ENSPTRG00000006910
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Location :
    chromosome: 15
    Sequence :
    Chromosome: 15; NC_006482.3 (36815286..36917223)
    See EIF2AK4 in MapViewer

    Chromosome 15 - NC_006482.3Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 176 Neighboring gene uncharacterized LOC100615661 Neighboring gene signal recognition particle 14kDa (homologous Alu RNA binding protein) Neighboring gene Bcl2 modifying factor Neighboring gene budding uninhibited by benzimidazoles 1 homolog beta (yeast)

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    • Epstein-Barr virus infection, organism-specific biosystem (from KEGG)
      Epstein-Barr virus infection, organism-specific biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Epstein-Barr virus infection, conserved biosystem (from KEGG)
      Epstein-Barr virus infection, conserved biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Hepatitis C, organism-specific biosystem (from KEGG)
      Hepatitis C, organism-specific biosystemHepatitis C virus (HCV) is a major cause of chronic liver disease. The HCV employ several strategies to perturb host cell immunity. After invasion, HCV RNA genome functions directly as an mRNA in the...
    • Hepatitis C, conserved biosystem (from KEGG)
      Hepatitis C, conserved biosystemHepatitis C virus (HCV) is a major cause of chronic liver disease. The HCV employ several strategies to perturb host cell immunity. After invasion, HCV RNA genome functions directly as an mRNA in the...
    • Herpes simplex infection, organism-specific biosystem (from KEGG)
      Herpes simplex infection, organism-specific biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
    • Herpes simplex infection, conserved biosystem (from KEGG)
      Herpes simplex infection, conserved biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
    • Influenza A, organism-specific biosystem (from KEGG)
      Influenza A, organism-specific biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
    • Influenza A, conserved biosystem (from KEGG)
      Influenza A, conserved biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
    • Measles, organism-specific biosystem (from KEGG)
      Measles, organism-specific biosystemMeasles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. It causes severe immunosuppression favouring secondary bacteri...
    • Measles, conserved biosystem (from KEGG)
      Measles, conserved biosystemMeasles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. It causes severe immunosuppression favouring secondary bacteri...
    • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
    • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...

    Markers

    Genotypes

    Homology

    Preferred Names
    eukaryotic translation initiation factor 2-alpha kinase 4
    Names
    eukaryotic translation initiation factor 2 alpha kinase 4

    RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 102

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Pan_troglodytes-2.1.4 Primary Assembly

    Genomic

    1. NC_006482.3

      Range
      36815286..36917223
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001140245.3 → XP_001140245.1  

      UniProtKB/TrEMBL
      H2Q956
      Related
      ENSPTRP00000011798, ENSPTRT00000012740
      Conserved Domains (8) summary
      cd00859
      Location:1396 – 1486
      Blast Score: 122
      HisRS_anticodon; HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is ...
      COG0124
      Location:1065 – 1490
      Blast Score: 301
      HisS; Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
      cd00180
      Location:797 – 998
      Blast Score: 357
      PKc; Catalytic domain of Protein Kinases
      PLN00034
      Location:665 – 1019
      Blast Score: 189
      PLN00034; mitogen-activated protein kinase kinase; Provisional
      smart00220
      Location:332 – 539
      Blast Score: 300
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam05773
      Location:21 – 134
      Blast Score: 258
      RWD; RWD domain
      cl00268
      Location:1061 – 1244
      Blast Score: 189
      class_II_aaRS-like_core; Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches ...
      cl09925
      Location:282 – 539
      Blast Score: 388
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    genomic AACZ03100157.1 (12939..30605) None
    genomic AACZ03100158.1 None
    genomic AACZ03100159.1 None
    genomic AACZ03100160.1 None

    Gene LinkOut

      Supplemental Content

      Table of contents

      Related information

      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP: Genotype
        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniSTS
        Related UniSTS records

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