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    MMP1 matrix metallopeptidase 1 (interstitial collagenase) [ Pan troglodytes (chimpanzee) ]

    Gene ID: 451510, updated on 21-May-2013
    Gene symbol
    MMP1
    Gene description
    matrix metallopeptidase 1 (interstitial collagenase)
    See related
    Ensembl:ENSPTRG00000023318
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Location :
    chromosome: 11
    Sequence :
    Chromosome: 11; NC_006478.3 (100637270..100645989, complement)
    See MMP1 in MapViewer

    Chromosome 11 - NC_006478.3Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 8 (neutrophil collagenase) Neighboring gene matrix metallopeptidase 10 (stromelysin 2) Neighboring gene casein kinase 1, alpha 1 pseudogene Neighboring gene matrix metallopeptidase 3 (stromelysin 1, progelatinase)

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    • Androgen Receptor Signaling Pathway, organism-specific biosystem (from WikiPathways)
      Androgen Receptor Signaling Pathway, organism-specific biosystemThe androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among ot...
    • Bladder cancer, organism-specific biosystem (from KEGG)
      Bladder cancer, organism-specific biosystemThe urothelium covers the luminal surface of almost the entire urinary tract, extending from the renal pelvis, through the ureter and bladder, to the proximal urethra. The majority of urothelial carc...
    • Bladder cancer, conserved biosystem (from KEGG)
      Bladder cancer, conserved biosystemThe urothelium covers the luminal surface of almost the entire urinary tract, extending from the renal pelvis, through the ureter and bladder, to the proximal urethra. The majority of urothelial carc...
    • Matrix Metalloproteinases, organism-specific biosystem (from WikiPathways)
      Matrix Metalloproteinases, organism-specific biosystemMatrix metalloproteinases (MMPs) are zinc-dependent endopeptidases; other family members are adamalysins, serralysins, and astacins. The MMPs belong to a larger family of proteases known as the metzi...
    • PPAR signaling pathway, organism-specific biosystem (from KEGG)
      PPAR signaling pathway, organism-specific biosystemPeroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated by fatty acids and their derivatives. PPAR has three subtypes (PPARalpha, beta/delta, and gamma) s...
    • PPAR signaling pathway, conserved biosystem (from KEGG)
      PPAR signaling pathway, conserved biosystemPeroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated by fatty acids and their derivatives. PPAR has three subtypes (PPARalpha, beta/delta, and gamma) s...
    • Pathways in cancer, organism-specific biosystem (from KEGG)
      Pathways in cancer, organism-specific biosystem
      Pathways in cancer
    • Rheumatoid arthritis, organism-specific biosystem (from KEGG)
      Rheumatoid arthritis, organism-specific biosystemRheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affects bone remodeling leading to progressive bone destruction. In RA, abnormal activation of the immune...
    • Rheumatoid arthritis, conserved biosystem (from KEGG)
      Rheumatoid arthritis, conserved biosystemRheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affects bone remodeling leading to progressive bone destruction. In RA, abnormal activation of the immune...

    Markers

    Homology

    Names
    matrix metallopeptidase 1 (interstitial collagenase)
    matrix metalloproteinase 1

    RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 102

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Pan_troglodytes-2.1.4 Primary Assembly

    Genomic

    1. NC_006478.3

      Range
      100637270..100645989, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003313276.1XP_003313324.1  

      Conserved Domains (3) summary
      cd00094
      Location:209400
      Blast Score: 576
      HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
      cd04278
      Location:42195
      Blast Score: 558
      ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
      pfam01471
      Location:121
      Blast Score: 97
      PG_binding_1; Putative peptidoglycan binding domain
    2. XM_508722.3XP_508722.2  

      UniProtKB/TrEMBL
      H2Q4N3
      Related
      ENSPTRP00000007262, ENSPTRT00000007870
      Conserved Domains (3) summary
      cd00094
      Location:275466
      Blast Score: 582
      HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
      cd04278
      Location:108261
      Blast Score: 563
      ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
      pfam01471
      Location:2787
      Blast Score: 146
      PG_binding_1; Putative peptidoglycan binding domain

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