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IL2RA interleukin 2 receptor, alpha [ Pan troglodytes (chimpanzee) ]

Gene ID: 450884, updated on 1-Feb-2015
Gene symbol
IL2RA
Gene description
interleukin 2 receptor, alpha
See related
Ensembl:ENSPTRG00000002263
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
See IL2RA in MapViewer
Location:
chromosome: 10
Exon count:
8
Annotation release Status Assembly Chr Location
103 current Pan_troglodytes-2.1.4 (GCF_000001515.6) 10 NC_006477.3 (6096208..6147438, complement)

Chromosome 10 - NC_006477.3Genomic Context describing neighboring genes Neighboring gene F-box protein, helicase, 18 Neighboring gene uncharacterized LOC747035 Neighboring gene interleukin 15 receptor, alpha Neighboring gene uncharacterized LOC104008091 Neighboring gene RNA binding motif protein 17 Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Genomic Sequence:
NC_006477.3 Chromosome 10 Reference Pan_troglodytes-2.1.4 Primary Assembly

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Cytokine-cytokine receptor interaction, organism-specific biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, organism-specific biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Cytokine-cytokine receptor interaction, conserved biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, conserved biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Endocytosis, organism-specific biosystem (from KEGG)
    Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
  • Endocytosis, conserved biosystem (from KEGG)
    Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
  • HTLV-I infection, organism-specific biosystem (from KEGG)
    HTLV-I infection, organism-specific biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
  • HTLV-I infection, conserved biosystem (from KEGG)
    HTLV-I infection, conserved biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
  • Hematopoietic cell lineage, organism-specific biosystem (from KEGG)
    Hematopoietic cell lineage, organism-specific biosystemBlood-cell development progresses from a hematopoietic stem cell (HSC), which can undergo either self-renewal or differentiation into a multilineage committed progenitor cell: a common lymphoid proge...
  • Hematopoietic cell lineage, conserved biosystem (from KEGG)
    Hematopoietic cell lineage, conserved biosystemBlood-cell development progresses from a hematopoietic stem cell (HSC), which can undergo either self-renewal or differentiation into a multilineage committed progenitor cell: a common lymphoid proge...
  • IL-2 Signaling Pathway, organism-specific biosystem (from WikiPathways)
    IL-2 Signaling Pathway, organism-specific biosystemInterleukin-2 belongs to a family of cytokines, which includes IL-4, IL-7, IL-9, IL-15 and IL-21. IL-2 signals through a receptor complex consisting of IL-2 specific IL-2 receptor alpha (CD25), IL-2 ...
  • Jak-STAT signaling pathway, organism-specific biosystem (from KEGG)
    Jak-STAT signaling pathway, organism-specific biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
  • Jak-STAT signaling pathway, conserved biosystem (from KEGG)
    Jak-STAT signaling pathway, conserved biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
  • Measles, organism-specific biosystem (from KEGG)
    Measles, organism-specific biosystemMeasles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. It causes severe immunosuppression favouring secondary bacteri...
  • Measles, conserved biosystem (from KEGG)
    Measles, conserved biosystemMeasles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. It causes severe immunosuppression favouring secondary bacteri...
  • PI3K-Akt signaling pathway, organism-specific biosystem (from KEGG)
    PI3K-Akt signaling pathway, organism-specific biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • PI3K-Akt signaling pathway, conserved biosystem (from KEGG)
    PI3K-Akt signaling pathway, conserved biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...

Markers

Homology

Preferred Names
interleukin-2 receptor subunit alpha
Names
interleukin-2 receptor subunit alpha
IL-2 receptor subunit alpha
IL-2-RA
IL-2R subunit alpha
IL2-RA
interleukin-2 receptor alpha chain

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001035520.1NP_001030597.1  interleukin-2 receptor subunit alpha precursor

    See identical proteins and their annotated locations for NP_001030597.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ226542
    UniProtKB/Swiss-Prot
    Q38IC8
    Conserved Domains (2) summary
    cd00033
    Location:125184
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    pfam00084
    Location:2678
    Sushi; Sushi domain (SCR repeat)

RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 103

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pan_troglodytes-2.1.4 Primary Assembly

Genomic

  1. NC_006477.3 Reference Pan_troglodytes-2.1.4 Primary Assembly

    Range
    6096208..6147438
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009457869.1XP_009456144.1  

    UniProtKB/TrEMBL
    H2Q1K9
    Related
    ENSPTRP00000003829, ENSPTRT00000004148
    Conserved Domains (2) summary
    cd00033
    Location:125184
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    pfam00084
    Location:2678
    Sushi; Sushi domain (SCR repeat)